Literature DB >> 28969210

Prevention of Parent to Child Transmission of HIV: Single Centre Experience of 14 years at Tertiary Care Hospital in Delhi, India.

A G Radhika1, Sonia Chawla2, Sruthi Bhaskaran3.   

Abstract

INTRODUCTION: Prevention of Parent To Child Transmission (PPTCT) of HIV/AIDS is an integral component of AIDS control programme. PPTCT is an ongoing programme since last 15 years. AIM: The aim of the study was to evaluate the reduction in the burden of disease in newborn and infants by prevention of parents to child transmission of HIV/AIDS.
MATERIALS AND METHODS: This retrospective study was conducted at Department of Obstetrics and Gynecology in a tertiary care hospital of Delhi from May 2002 to May 2015. The data was collected from records of maternal details registered at PPTCT clinic as well as list of infants undergoing Early Infant Diagnosis (EID) recorded in the standard format as per instructions from National AIDS Control Organization (NACO) of India. The Programme performance was assessed against performance indicators stated by NACO, India.
RESULTS: Evaluation was done by dividing study period into two halves of seven years each. Out of 2,52,447 new antenatal case registration, overall, 43% received pretest of which, 91% were tested. Antenatal seropositivity rate varied from 0.1%-0.25%. Of 243 seropositive antenatal women 187 partners tested positive. While 25 women opted for MTP, 15 had still births. There were 17 neonatal deaths at 3-12 months attributable to respiratory infections and diarrheal diseases. Operative delivery rates declined from 50% to 31% over the years. Most women opted for breast feeding. The lost to follow up rate of newborns was quite high with details of only 43.5% being available at 18 months of infant's age. A total of three infants tested HIV positive at 18 months of age.
CONCLUSION: The study highlights the practical aspects of policy implementation and operational issues involved in low resource country.

Entities:  

Keywords:  Antenatal woman; Antiretroviral therapy; Nevirapine

Year:  2017        PMID: 28969210      PMCID: PMC5620851          DOI: 10.7860/JCDR/2017/26432.10423

Source DB:  PubMed          Journal:  J Clin Diagn Res        ISSN: 0973-709X


  20 in total

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2.  Utilization of therapeutic intervention to prevent mother to child transmission of HIV in a teaching hospital in Kolkata, India.

Authors:  Snehamay Chaudhuri; Malay Mundle; Hiralal Konar; Chandana Das; Arunansu Talukdar; Uday Sankar Ghosh
Journal:  J Obstet Gynaecol Res       Date:  2010-06       Impact factor: 1.730

3.  Evaluation of a 5-year programme to prevent mother-to-child transmission of HIV infection in Northern Uganda.

Authors:  Laurence Ahoua; Harriet Ayikoru; Katherine Gnauck; Grace Odaru; Emmanuel Odar; Christine Ondoa-Onama; Loretxu Pinoges; Suna Balkan; David Olson; Mar Pujades-Rodríguez
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Review 4.  From caution to urgency: the evolution of HIV testing and counselling in Africa.

Authors:  R Baggaley; B Hensen; O Ajose; K L Grabbe; V J Wong; A Schilsky; Y-R Lo; F Lule; R Granich; J Hargreaves
Journal:  Bull World Health Organ       Date:  2012-06-27       Impact factor: 9.408

5.  Assessment of utilisation of PMTCT services at Nyanza Provincial Hospital, Kenya.

Authors:  I A Moth; A B C O Ayayo; D O Kaseje
Journal:  SAHARA J       Date:  2005-07

6.  Effectiveness of a prevention of mother-to-child HIV transmission programme in an urban hospital in Angola.

Authors:  Cristina Lussiana; Sofia Vanda Lôa Clemente; Angelo Ghelardi; Magda Lonardi; Ivan Alejandro Pulido Tarquino; Marco Floridia
Journal:  PLoS One       Date:  2012-04-30       Impact factor: 3.240

7.  Effectiveness of option B highly active antiretroviral therapy (HAART) prevention of mother-to-child transmission (PMTCT) in pregnant HIV women.

Authors:  Erastus K Ngemu; Christopher Khayeka-Wandabwa; Eliningaya J Kweka; Joseph K Choge; Edward Anino; Elijah Oyoo-Okoth
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8.  Performance evaluation of PPTCT (Prevention of parent to child transmission of HIV) programme: an experience from West Bengal.

Authors:  Shuvankar Mukherjee; Santanu Ghosh; Dipendra Narayan Goswami; Amrita Samanta
Journal:  Indian J Med Res       Date:  2012-12       Impact factor: 2.375

9.  The impact of a HIV prevention of mother to child transmission program in a nigerian early infant diagnosis centre.

Authors:  Iregbu Kenneth Chukwuemeka; Modibbo Isa Fatima; Zubair Kabiru Ovavi; Olaitan Olukayode
Journal:  Niger Med J       Date:  2014-05

10.  Performance of the prevention of parent to child transmission program: A decadal trend from rural Maharashtra, India.

Authors:  R V Mohite; V R Mohite
Journal:  Indian J Sex Transm Dis AIDS       Date:  2016 Jan-Jun
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  2 in total

1.  Seroprevalence and Efficacy of Prevention of Parent to Child Transmission Program Over a Decade in a Tertiary Care Hospital in Mumbai, Maharashtra.

Authors:  Deepali Swapnil Kapote; Michelle N Fonseca; Arun Harishchandra Nayak; Swathi H Vishwabharati; Apeksha Mohite
Journal:  J Obstet Gynaecol India       Date:  2021-04-23

2.  Occurrence of vernal keratoconjunctivitis in children infected with human immunodeficiency virus.

Authors:  Vaishali L Une; Sourabh M Jadhav
Journal:  Indian J Ophthalmol       Date:  2022-02       Impact factor: 2.969

  2 in total

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