INTRODUCTION: Diagnosis of arterial ischemic stroke in pediatric patients is often delayed due to the uncertainty and variability of clinical symptoms. Early diagnosis of arterial ischemic stroke can bring a favorable prognosis with prompt thrombolytic therapy or stent insertion, via transfemoral cerebral arteriogram. Acute thrombolytic therapy is rarely attempted in children because of the delayed diagnosis. PATIENT AND METHOD: We report a case of a 4-year-old girl with complex heart disease who was presented with arterial ischemic stroke at the right distal internal carotid artery and successfully treated by stent insertion in which repeated thrombolysis or ballooning had failed. RESULT: Left hemiparesis was nearly recovered 6 days after the stent insertion. The mean flow velocity of the right middle cerebral artery has slightly improved compared to that of the initial study. She has been followed-up for 6 months in the outpatient clinic without neurologic sequelae. CONCLUSION: This case suggests that intracranial stent insertion may be a safe and an effective modality in young children, when the thrombolytic therapy or ballooning is inapplicable. Additionally, transcranial Doppler ultrasonography is useful to monitor the cerebral blood flow after stent insertion in children.
INTRODUCTION: Diagnosis of arterial ischemic stroke in pediatric patients is often delayed due to the uncertainty and variability of clinical symptoms. Early diagnosis of arterial ischemic stroke can bring a favorable prognosis with prompt thrombolytic therapy or stent insertion, via transfemoral cerebral arteriogram. Acute thrombolytic therapy is rarely attempted in children because of the delayed diagnosis. PATIENT AND METHOD: We report a case of a 4-year-old girl with complex heart disease who was presented with arterial ischemic stroke at the right distal internal carotid artery and successfully treated by stent insertion in which repeated thrombolysis or ballooning had failed. RESULT: Left hemiparesis was nearly recovered 6 days after the stent insertion. The mean flow velocity of the right middle cerebral artery has slightly improved compared to that of the initial study. She has been followed-up for 6 months in the outpatient clinic without neurologic sequelae. CONCLUSION: This case suggests that intracranial stent insertion may be a safe and an effective modality in young children, when the thrombolytic therapy or ballooning is inapplicable. Additionally, transcranial Doppler ultrasonography is useful to monitor the cerebral blood flow after stent insertion in children.
Authors: Kyle M Fargen; Brian L Hoh; Babu G Welch; G Lee Pride; Giuseppe Lanzino; Alan S Boulos; Jeffrey S Carpenter; Ansaar Rai; Erol Veznedaroglu; Andrew Ringer; Rafael Rodriguez-Mercado; Peter Kan; Adnan Siddiqui; Elad I Levy; J Mocco Journal: Neurosurgery Date: 2012-08 Impact factor: 4.654
Authors: Alexander A Khalessi; Sabareesh K Natarajan; David Orion; Mandy J Binning; Adnan Siddiqui; Elad I Levy; L Nelson Hopkins Journal: JACC Cardiovasc Interv Date: 2011-03 Impact factor: 11.195
Authors: C Roth; P Papanagiotou; S Behnke; S Walter; A Haass; C Becker; K Fassbender; M Politi; H Körner; M-S Romann; W Reith Journal: Stroke Date: 2010-10-14 Impact factor: 7.914
Authors: J Mocco; Ricardo A Hanel; Jitendra Sharma; Erik F Hauck; Kenneth V Snyder; Sabareesh K Natarajan; Italo Linfante; Adnan H Siddiqui; L Nelson Hopkins; Alan S Boulos; Elad I Levy Journal: J Neurosurg Date: 2010-03 Impact factor: 5.115