Literature DB >> 22842359

Micronuclei assay of exfoliated oral buccal cells: means to assess the nuclear abnormalities in different diseases.

Bina Kashyap1, Padala Sridhar Reddy.   

Abstract

The micronuclei assay (MA) in exfoliated buccal cells is an innovative genotoxicity technique, which holds promise for the study of epithelial carcinogens. Micronuclei are suitable internal dosimeters for revealing tissue-specific genotoxic damage in individuals exposed to carcinogenic mixtures. This article reviews the MN assay with respect to oral buccal mucosa, which has been used since the 1980s to demonstrate cytogenetic effects of environmental and occupational exposures, lifestyle factors, dietary deficiencies, and different diseases along with the characteristics of micronuclei and other nuclear abnormalities.

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Year:  2012        PMID： 22842359     DOI： 10.4103/0973-1482.98968

Source DB:  PubMed          Journal:  J Cancer Res Ther        ISSN： 1998-4138            Impact factor:   1.805


  27 in total

1.  The Micronuclei Scoring as a Biomarker for Early Detection of Genotoxic Effect of Cigarette Smoking.

Authors:  Asmaa M Mohammed; Dalia F Hussen; Hend Rashad; Adel Hasheesh
Journal:  Asian Pac J Cancer Prev       Date:  2020-01-01

2.  Cytogenetic damage in the oral mucosa cells of bladder cancer patients exposed to tobacco in Southern Tunisia.

Authors:  Molka Feki-Tounsi; Rim Khlifi; Mohamed-Nabil Mhiri; Ahmed Rebai; Amel Hamza-Chaffai
Journal:  Environ Sci Pollut Res Int       Date:  2014-07-02       Impact factor: 4.223

3.  Shisha smoking: An emerging trend in Southeast Asian nations.

Authors:  Srinivas S Ramachandra; Ali Yaldrum
Journal:  J Public Health Policy       Date:  2015-08       Impact factor: 2.222

4.  Induced cytotoxic damage by exposure to gasoline vapors: a study in Sinaloa, Mexico.

Authors:  Carmen Martinez-Valenzuela; Fernanda Balderrama Soto; Stefan M Waliszewski; Enrique Meza; Sandra Gómez Arroyo; Luis Daniel Ortega Martínez; Eliakym Arambula Meraz; Mario Caba
Journal:  Environ Sci Pollut Res Int       Date:  2016-10-12       Impact factor: 4.223

5.  Can Feulgen Stain be a Reliable Biomarker over PAP Stain for Estimation of Micronuclei Score?

Authors:  Manish Kumar; Umesh Chandra Prasad; Betina Chandolia; S M Manjunath; Shiva Basu; Silvie Verma
Journal:  J Clin Diagn Res       Date:  2016-10-01

6.  Evidence of genotoxicity and cytotoxicity of X-rays in the oral mucosa epithelium of adults subjected to cone beam CT.

Authors:  Juliana Bm da Fonte; Taís M de Andrade; Ricardo Lc Albuquerque; Maria de Fátima B de Melo; Wilton M Takeshita
Journal:  Dentomaxillofac Radiol       Date:  2017-11-13       Impact factor: 2.419

Review 7.  Noninvasive effects measurements for air pollution human studies: methods, analysis, and implications.

Authors:  Jaime Mirowsky; Terry Gordon
Journal:  J Expo Sci Environ Epidemiol       Date:  2015-01-21       Impact factor: 5.563

8.  Abnormal Nuclear Variations in Response to Radiotherapy- As a Tool in Treatment Planning and Assessment of Prognosis.

Authors:  Kumar Satish Ravi; Manisha Naithani; Sohinder Kaur; K S Reddy; Rachna Pasi
Journal:  J Clin Diagn Res       Date:  2016-08-01

9.  Evaluation of genotoxic and cytotoxic effects in buccal mucosa cells of welders in the cities of Cubatão and Santos, state of São Paulo, Brazil.

Authors:  Laiane Damara Oliveira do Vale; Victor Hugo Pereira da Silva; Flavio Rossi de Almeida; Daniel Araki Ribeiro; Daniela Martins da Silva
Journal:  Rev Bras Med Trab       Date:  2017-12-01

Review 10.  Genotoxic Effect in Autoimmune Diseases Evaluated by the Micronucleus Test Assay: Our Experience and Literature Review.

Authors:  Olivia Torres-Bugarín; Nicole Macriz Romero; María Luisa Ramos Ibarra; Aurelio Flores-García; Penélope Valdez Aburto; María Guadalupe Zavala-Cerna
Journal:  Biomed Res Int       Date:  2015-08-03       Impact factor: 3.411
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