Literature DB >> 22834935

Antisocial symptoms decrease to normal levels in long-term abstinence.

George Fein1, David Fein.   

Abstract

BACKGROUND: We have previously shown highly elevated antisocial symptoms and measures of social deviance proneness and antisocial disposition in long-term abstinent alcohol dependence versus non-substance-abusing controls (NSAC). Current antisocial symptoms were reduced to subdiagnostic levels in long-term abstinence; however, the number of current symptoms was not measured beyond its being subdiagnostic.
METHODS: Here we measured social deviance proneness, antisocial disposition, and both lifetime and current antisocial symptoms in short-term and long-term abstinent substance-dependent and NSAC samples.
RESULTS: Lifetime antisocial symptoms (and diagnoses) and social deviance proneness and antisocial disposition were highly elevated in both short- and long-term abstinence, replicating earlier findings. Current antisocial symptoms were dramatically reduced in long-term versus short-term abstinent samples, close to levels in controls. In contrast, social deviance proneness and antisocial disposition remain highly elevated in long-term abstinence.
CONCLUSIONS: These findings suggest that antisocial behavior is reduced in extended abstinence, despite continued elevated social deviance proneness an antisocial disposition. This suggests a top-down model in extended abstinence, whereby executive control inhibits deviance-prone tendencies.
Copyright © 2012 by the Research Society on Alcoholism.

Entities:  

Mesh:

Year:  2012        PMID: 22834935     DOI: 10.1111/j.1530-0277.2012.01904.x

Source DB:  PubMed          Journal:  Alcohol Clin Exp Res        ISSN: 0145-6008            Impact factor:   3.455


  6 in total

1.  Familial association of abstinent remission from alcohol use disorder in first-degree relatives of alcohol-dependent treatment-seeking probands.

Authors:  Vivia V McCutcheon; Marc A Schuckit; John R Kramer; Grace Chan; Howard J Edenberg; Tom L Smith; Annah K Bender; Victor Hesselbrock; Michie Hesselbrock; Kathleen K Bucholz
Journal:  Addiction       Date:  2017-07-06       Impact factor: 6.526

2.  Resting-state synchrony in short-term versus long-term abstinent alcoholics.

Authors:  Jazmin Camchong; Victor Andrew Stenger; George Fein
Journal:  Alcohol Clin Exp Res       Date:  2013-02-19       Impact factor: 3.455

3.  Psychiatric Comorbidity in Alcohol Dependence.

Authors:  George Fein
Journal:  Neuropsychol Rev       Date:  2015-11-21       Impact factor: 7.444

4.  Lifetime and current mood and anxiety disorders in short-term and long-term abstinent alcoholics.

Authors:  George Fein
Journal:  Alcohol Clin Exp Res       Date:  2013-07-29       Impact factor: 3.455

Review 5.  Neuroplasticity in Human Alcoholism: Studies of Extended Abstinence with Potential Treatment Implications.

Authors:  George Fein; Valerie A Cardenas
Journal:  Alcohol Res       Date:  2015

6.  EEG coherence related to fMRI resting state synchrony in long-term abstinent alcoholics.

Authors:  Valerie A Cardenas; Mathew Price; George Fein
Journal:  Neuroimage Clin       Date:  2017-11-08       Impact factor: 4.881

  6 in total

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