BACKGROUND: Health-related quality of life (HRQOL) is an essential subject for children with end-stage renal disease (ESRD) and their families. METHODS: We performed a cross-sectional investigation of HRQOL in children undergoing renal replacement therapies, such as dialysis and renal transplantation, using the 34-item Pediatric Quality of Life Inventory 3.0 End-Stage Renal Disease (PedsQL 3.0 ESRD) module. We assessed 92 ESRD patients aged 2-18 from four Korean university hospitals. RESULTS: The male:female ratio was 44:48, and the most common cause of ESRD was chronic glomerulonephritis. Fifty-five children were treated by dialysis, and 37 received renal transplantation. Transplant patients had better HRQOL than dialysis patients in two domains in parent proxy reports: "About my kidney disease" and "Worry." In child self-reports, transplant patients had better HRQOL than dialysis patients in one domain: Treatment problems. However, there were no significant differences in total QOL scores between peritoneal dialysis (PD) and transplant patients in child self-reports. In addition, there were differences in the ESRD module scores between child self- and parent proxy reports. Children usually reported better QOL than their parents. Child self-reports showed significantly higher QOL scores than parent proxy reports in the domains of General fatigue, Family & peer interaction, and Worry. Children on PD self-reported a significantly higher QOL than children on hemodialysis (HD). CONCLUSIONS: The PedsQL 3.0 ESRD module may be useful as an ESRD-specific instrument to evaluate HRQOL in children; however, a larger, longitudinal prospective study is warranted.
BACKGROUND: Health-related quality of life (HRQOL) is an essential subject for children with end-stage renal disease (ESRD) and their families. METHODS: We performed a cross-sectional investigation of HRQOL in children undergoing renal replacement therapies, such as dialysis and renal transplantation, using the 34-item Pediatric Quality of Life Inventory 3.0 End-Stage Renal Disease (PedsQL 3.0 ESRD) module. We assessed 92 ESRDpatients aged 2-18 from four Korean university hospitals. RESULTS: The male:female ratio was 44:48, and the most common cause of ESRD was chronic glomerulonephritis. Fifty-five children were treated by dialysis, and 37 received renal transplantation. Transplant patients had better HRQOL than dialysis patients in two domains in parent proxy reports: "About my kidney disease" and "Worry." In child self-reports, transplant patients had better HRQOL than dialysis patients in one domain: Treatment problems. However, there were no significant differences in total QOL scores between peritoneal dialysis (PD) and transplant patients in child self-reports. In addition, there were differences in the ESRD module scores between child self- and parent proxy reports. Children usually reported better QOL than their parents. Child self-reports showed significantly higher QOL scores than parent proxy reports in the domains of General fatigue, Family & peer interaction, and Worry. Children on PD self-reported a significantly higher QOL than children on hemodialysis (HD). CONCLUSIONS: The PedsQL 3.0 ESRD module may be useful as an ESRD-specific instrument to evaluate HRQOL in children; however, a larger, longitudinal prospective study is warranted.
Authors: I H Khan; M K Campbell; D Cantarovich; G R Catto; C Delcroix; N Edward; C Fontenaille; L W Fleming; P G Gerlag; H W van Hamersvelt; I S Henderson; R A Koene; M Papadimitriou; E Ritz; I T Russell; E Stier; D Tsakiris; A M MacLeod Journal: Nephrol Dial Transplant Date: 1996-02 Impact factor: 5.992
Authors: Silvia Wiedebusch; Martin Konrad; Helmut Foppe; Evelyn Reichwald-Klugger; Franz Schaefer; Vera Schreiber; Fritz A Muthny Journal: Pediatr Nephrol Date: 2010-05-12 Impact factor: 3.714
Authors: Jeffrey Fadrowski; Stephen R Cole; Wenke Hwang; Jeffrey Fiorenza; Robert A Weiss; Arlene Gerson; Susan L Furth Journal: Pediatr Nephrol Date: 2005-12-29 Impact factor: 3.714
Authors: Jeannette G Van Manen; Johanna C Korevaar; Friedo W Dekker; Elisabeth W Boeschoten; Patrick M M Bossuyt; Raymond T Krediet Journal: J Am Soc Nephrol Date: 2003-02 Impact factor: 10.121
Authors: Jutta Falger; Markus A Landolt; Bea Latal; Eva M Rüth; Thomas J Neuhaus; Guido F Laube Journal: Pediatr Nephrol Date: 2008-04-03 Impact factor: 3.714
Authors: Stuart L Goldstein; Nicole Graham; Bradley A Warady; Mouin Seikaly; Ruth McDonald; Tasha M Burwinkle; Christine A Limbers; James W Varni Journal: Am J Kidney Dis Date: 2008-02 Impact factor: 8.860
Authors: David T Selewski; Susan F Massengill; Jonathan P Troost; Larysa Wickman; Kassandra L Messer; Emily Herreshoff; Corinna Bowers; Maria E Ferris; John D Mahan; Larry A Greenbaum; Jackie MacHardy; Gaurav Kapur; Deepa H Chand; Jens Goebel; Gina Marie Barletta; Denis Geary; David B Kershaw; Cynthia G Pan; Rasheed Gbadegesin; Guillermo Hidalgo; Jerome C Lane; Jeffrey D Leiser; Peter X Song; David Thissen; Yang Liu; Heather E Gross; Darren A DeWalt; Debbie S Gipson Journal: Pediatr Nephrol Date: 2014-06-09 Impact factor: 3.714
Authors: Joann Carlson; Arlene C Gerson; Matthew B Matheson; Sharon Manne; Bradley A Warady; Stephen R Hooper; Marc Lande; Lyndsay A Harshman; Rebecca J Johnson; Shlomo Shinnar; Amy J Kogon; Susan Furth Journal: Pediatr Nephrol Date: 2020-04-24 Impact factor: 3.714