Literature DB >> 22814658

The current state of therapeutic drug trials in pregnancy.

S Endicott1, D M Haas.   

Abstract

The majority of pregnant women take prescription drugs during their pregnancy. Given the multitude of physiologic changes incumbent in pregnancy, accurate clinical trial data on drugs in pregnancy are crucial. This report summarizes the 264 registered clinical trials in the past two years. With many of these drug trials being pharmacokinetic and placebo-controlled studies, therapeutic drug trials are becoming more common.

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Year:  2012        PMID： 22814658     DOI： 10.1038/clpt.2012.81

Source DB:  PubMed          Journal:  Clin Pharmacol Ther        ISSN： 0009-9236            Impact factor:   6.875


  10 in total

Review 1.  Pharmacogenetics and individualizing drug treatment during pregnancy.

Authors:  David M Haas
Journal:  Pharmacogenomics       Date:  2014-01       Impact factor: 2.533

Review 2.  Placental control of drug delivery.

Authors:  Sanaalarab Al-Enazy; Shariq Ali; Norah Albekairi; Marwa El-Tawil; Erik Rytting
Journal:  Adv Drug Deliv Rev       Date:  2016-08-12       Impact factor: 15.470

3.  Characteristics and publication patterns of obstetric studies registered in ClinicalTrials.gov.

Authors:  Chris Stockmann; Catherine M T Sherwin; Gideon Koren; Sarah C Campbell; Jonathan E Constance; Matthew Linakis; Alfred Balch; Michael W Varner; Michael G Spigarelli
Journal:  J Clin Pharmacol       Date:  2013-11-14       Impact factor: 3.126

4.  Prescription and Other Medication Use in Pregnancy.

Authors:  David M Haas; Derek J Marsh; Danny T Dang; Corette B Parker; Deborah A Wing; Hyagriv N Simhan; William A Grobman; Brian M Mercer; Robert M Silver; Matthew K Hoffman; Samuel Parry; Jay D Iams; Steve N Caritis; Ronald J Wapner; M Sean Esplin; Michal A Elovitz; Alan M Peaceman; Judith Chung; George R Saade; Uma M Reddy
Journal:  Obstet Gynecol       Date:  2018-05       Impact factor: 7.661

5.  Assessing the information in the Summaries of Product Characteristics for the use of medicines in pregnancy and lactation.

Authors:  Blanca Arguello; Teresa M Salgado; Fernando Fernandez-Llimos
Journal:  Br J Clin Pharmacol       Date:  2015-03       Impact factor: 4.335

Review 6.  Pharmacologic studies in vulnerable populations: Using the pediatric experience.

Authors:  Kanecia Zimmerman; Daniel Gonzalez; Geeta K Swamy; Michael Cohen-Wolkowiez
Journal:  Semin Perinatol       Date:  2015-09-08       Impact factor: 3.311

7.  Lessons learned in pediatric clinical research to evaluate safe and effective use of drugs in pregnancy.

Authors:  Daniel Gonzalez; Kim A Boggess; Michael Cohen-Wolkowiez
Journal:  Obstet Gynecol       Date:  2015-04       Impact factor: 7.623

Review 8.  Sex-Gender Variable: Methodological Recommendations for Increasing Scientific Value of Clinical Studies.

Authors:  Flavia Franconi; Ilaria Campesi; Delia Colombo; Paola Antonini
Journal:  Cells       Date:  2019-05-17       Impact factor: 6.600

9.  Application of physiologically based pharmacokinetic modeling for sertraline dosing recommendations in pregnancy.

Authors:  Blessy George; Annie Lumen; Christine Nguyen; Barbara Wesley; Jian Wang; Julie Beitz; Victor Crentsil
Journal:  NPJ Syst Biol Appl       Date:  2020-11-06

10.  Protocol of a prospective and multicentre China Teratology Birth Cohort (CTBC): association of maternal drug exposure during pregnancy with adverse pregnancy outcomes.

Authors:  Jun Zhu; Xiaohong Li; Yangwen Zhou; Jing Tao; Ke Wang; Kui Deng; Yanping Wang; Jianxin Zhao; Chunyi Chen; Tingxuan Wu; Jiayuan Zhou
Journal:  BMC Pregnancy Childbirth       Date:  2021-09-01       Impact factor: 3.007
  10 in total

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