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Literature DB >> 22811820

Obesity, insulin and chemoresistance in colon cancer.

Andrew G Renehan¹, Caroline Dive.

Abstract

Entities: Disease Gene

Year: 2011 PMID： 22811820 PMCID： PMC3397595 DOI： 10.3978/j.issn.2078-6891.2011.010

Source DB: PubMed Journal: J Gastrointest Oncol ISSN： 2078-6891

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12 in total

1. Comparison of phosphatidylinositol-3-kinase signalling within a panel of human colorectal cancer cell lines with mutant or wild-type PIK3CA.

Authors: Christopher J Morrow; Alexander Gray; Caroline Dive
Journal: FEBS Lett Date: 2005-09-26 Impact factor: 4.124

2. Obesity is an independent prognostic variable in colon cancer survivors.

Authors: Frank A Sinicrope; Nathan R Foster; Daniel J Sargent; Michael J O'Connell; Cathryn Rankin
Journal: Clin Cancer Res Date: 2010-03-09 Impact factor: 12.531

3. Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

Authors: Yardena Samuels; Luis A Diaz; Oleg Schmidt-Kittler; Jordan M Cummins; Laura Delong; Ian Cheong; Carlo Rago; David L Huso; Christoph Lengauer; Kenneth W Kinzler; Bert Vogelstein; Victor E Velculescu
Journal: Cancer Cell Date: 2005-06 Impact factor: 31.743

4. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

Authors: Eek Joong Park; Jun Hee Lee; Guann-Yi Yu; Guobin He; Syed Raza Ali; Ryan G Holzer; Christoph H Osterreicher; Hiroyuki Takahashi; Michael Karin
Journal: Cell Date: 2010-01-22 Impact factor: 41.582

5. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

Authors: Eugenia E Calle; Carmen Rodriguez; Kimberly Walker-Thurmond; Michael J Thun
Journal: N Engl J Med Date: 2003-04-24 Impact factor: 91.245

6. Visceral fat area is an independent predictive biomarker of outcome after first-line bevacizumab-based treatment in metastatic colorectal cancer.

Authors: Boris Guiu; Jean Michel Petit; Franck Bonnetain; Sylvain Ladoire; Séverine Guiu; Jean-Pierre Cercueil; Denis Krausé; Patrick Hillon; Christophe Borg; Bruno Chauffert; François Ghiringhelli
Journal: Gut Date: 2009-10-15 Impact factor: 23.059

7. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004).

Authors: Rachel P Wildman; Paul Muntner; Kristi Reynolds; Aileen P McGinn; Swapnil Rajpathak; Judith Wylie-Rosett; MaryFran R Sowers
Journal: Arch Intern Med Date: 2008-08-11

3. High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.

Authors: Guosheng Han; Laixing Wang; Wenyuan Zhao; Zhijian Yue; Rui Zhao; Yanan Li; Xiaoping Zhou; Xiaowu Hu; Jianmin Liu
Journal: Cell Cycle Date: 2013-10-16 Impact factor: 4.534

3 in total

Obesity, insulin and chemoresistance in colon cancer.

1. Comparison of phosphatidylinositol-3-kinase signalling within a panel of human colorectal cancer cell lines with mutant or wild-type PIK3CA.

2. Obesity is an independent prognostic variable in colon cancer survivors.

3. Mutant PIK3CA promotes cell growth and invasion of human cancer cells.

4. Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression.

5. Overweight, obesity, and mortality from cancer in a prospectively studied cohort of U.S. adults.

6. Visceral fat area is an independent predictive biomarker of outcome after first-line bevacizumab-based treatment in metastatic colorectal cancer.

7. The obese without cardiometabolic risk factor clustering and the normal weight with cardiometabolic risk factor clustering: prevalence and correlates of 2 phenotypes among the US population (NHANES 1999-2004).

8. Intrahepatic fat, not visceral fat, is linked with metabolic complications of obesity.

Review 9. Biological mechanisms linking obesity and cancer risk: new perspectives.

10. The selectivity of protein kinase inhibitors: a further update.

Review 1. Roles of the PI3K/Akt pathway in Epstein-Barr virus-induced cancers and therapeutic implications.

2. Changes in Adult BMI and Waist Circumference Are Associated with Increased Risk of Advanced Colorectal Neoplasia.

3. High expression of leptin receptor leads to temozolomide resistance with exhibiting stem/progenitor cell features in gliobalastoma.