Literature DB >> 22805176

Phenylpropanoids from Phragmipedium calurum and their antiproliferative activity.

Courtney M Starks1, Russell B Williams, Vanessa L Norman, Julie A Lawrence, Mark O'Neil-Johnson, Gary R Eldridge.   

Abstract

Seven stilbenes and one alkylresorcinol were isolated from the orchid Phragmipedium calurum during a screen for anticancer compounds. They were evaluated for antiproliferative activity against multiple human cancer cell lines, and two displayed moderate activity against several cell lines.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID： 22805176      PMCID： PMC3425716          DOI： 10.1016/j.phytochem.2012.06.017

Source DB:  PubMed          Journal:  Phytochemistry        ISSN： 0031-9422            Impact factor:   4.072


  9 in total

1.  Resorcinolic Lipids, the Natural Non-isoprenoid Phenolic Amphiphiles and Their Biological Activity.

Authors:  Arkadiusz Kozubek; John H. P. Tyman
Journal:  Chem Rev       Date:  1999-01-13       Impact factor: 60.622

2.  Alkylresorcinol synthases expressed in Sorghum bicolor root hairs play an essential role in the biosynthesis of the allelopathic benzoquinone sorgoleone.

Authors:  Daniel Cook; Agnes M Rimando; Thomas E Clemente; Joachim Schröder; Franck E Dayan; N P Dhammika Nanayakkara; Zhiqiang Pan; Brice P Noonan; Mark Fishbein; Ikuro Abe; Stephen O Duke; Scott R Baerson
Journal:  Plant Cell       Date:  2010-03-26       Impact factor: 11.277

3.  Application of capillary-scale NMR for the structure determination of phytochemicals.

Authors:  Jin-Feng Hu; Eliane Garo; Hye-Dong Yoo; Peadar A Cremin; Lu Zeng; Matt G Goering; Mark O'Neil-Johnson; Gary R Eldridge
Journal:  Phytochem Anal       Date:  2005 Mar-Apr       Impact factor: 3.373

4.  Combining targeted drugs to stop resistant tumors.

Authors:  Jocelyn Kaiser
Journal:  Science       Date:  2011-03-25       Impact factor: 47.728

5.  Can treatment costs be tamed?

Authors:  David Malakoff
Journal:  Science       Date:  2011-03-25       Impact factor: 47.728

6.  Pentaketide resorcylic acid synthesis by type III polyketide synthase from Neurospora crassa.

Authors:  Nobutaka Funa; Takayoshi Awakawa; Sueharu Horinouchi
Journal:  J Biol Chem       Date:  2007-03-20       Impact factor: 5.157

7.  Alkylresorcinol biosynthesis in plants: new insights from an ancient enzyme family?

Authors:  Scott R Baerson; Joachim Schröder; Daniel Cook; Agnes M Rimando; Zhiqiang Pan; Franck E Dayan; Brice P Noonan; Stephen O Duke
Journal:  Plant Signal Behav       Date:  2010-10-01

8.  Projections of the cost of cancer care in the United States: 2010-2020.

Authors:  Angela B Mariotto; K Robin Yabroff; Yongwu Shao; Eric J Feuer; Martin L Brown
Journal:  J Natl Cancer Inst       Date:  2011-01-12       Impact factor: 13.506

9.  Stilbenes from the Orchid Phragmipedium sp.

Authors:  Eliane Garo; Jin-Feng Hu; Matt Goering; Grayson Hough; Mark O'Neil-Johnson; Gary Eldridge
Journal:  J Nat Prod       Date:  2007-05-31       Impact factor: 4.050
  9 in total
  2 in total

Review 1.  The re-emergence of natural products for drug discovery in the genomics era.

Authors:  Alan L Harvey; RuAngelie Edrada-Ebel; Ronald J Quinn
Journal:  Nat Rev Drug Discov       Date:  2015-01-23       Impact factor: 84.694

Review 2.  Metabolomics in the Context of Plant Natural Products Research: From Sample Preparation to Metabolite Analysis.

Authors:  Mohamed A Salem; Leonardo Perez de Souza; Ahmed Serag; Alisdair R Fernie; Mohamed A Farag; Shahira M Ezzat; Saleh Alseekh
Journal:  Metabolites       Date:  2020-01-15
  2 in total

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