Literature DB >> 22803112

Role of polymorphic variants of MTR gene A2756G and SHMT1 gene C1420T in the development of prostatic cancer in residents of the Western Siberian Region of Russia.

A S Weiner1, N A Oskina, A F Lacarev, V D Petrova, D I Ganov, U A Boyarskih, O G Tonacheva, E N Voronina, M L Filipenko.   

Abstract

Allelic variants of folate cycle enzyme genes can contribute to predisposition to cancer. The impact of polymorphic loci A2756G of MTR gene and of C1420T of SHMT1 gene for the risk of prostatic cancer was studied in residents of West Siberia. The frequency of alleles of these loci in patients (N=371) and controls (N=285) was determined and the data were statistically processed. No statistically significant association with prostatic cancer was detected for any of the studied loci.

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Year:  2012        PMID: 22803112     DOI: 10.1007/s10517-012-1554-6

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN: 0007-4888            Impact factor:   0.804


  3 in total

1.  Human methionine synthase A2756G polymorphism increases susceptibility to prostate cancer.

Authors:  Hong-Bao Shao; Kewei Ren; Sheng-Lin Gao; Jian-Gang Zou; Yuan-Yuan Mi; Li-Feng Zhang; Li Zuo; Atsushi Okada; Takahiro Yasui
Journal:  Aging (Albany NY)       Date:  2018-07-31       Impact factor: 5.682

Review 2.  A single-nucleotide polymorphism (rs1805087) in the methionine synthase (METH) gene increases the risk of prostate cancer.

Authors:  Xiaosong Zhang; Jilei Tang; Nan Shen; Kewei Ren
Journal:  Aging (Albany NY)       Date:  2018-10-18       Impact factor: 5.682

3.  Update analysis on the association between Methionine synthase rs1805087 A/G variant and risk of prostate cancer.

Authors:  Wei Zhang; Ze Zhang; Hao Wu; Kai Xu; Wei Yuan; Yuan-Yuan Mi; Li Shi; Li Zuo; Yun-Feng Shi
Journal:  Sci Rep       Date:  2020-08-07       Impact factor: 4.379

  3 in total

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