| Literature DB >> 2280024 |
A M Di Bisceglie1, J H Hoofnagle.
Abstract
Southern blot analysis of splenic DNA from three patients with chronic hepatitis B revealed the presence of replicative intermediate forms of viral DNA. Hepatitis B viral RNA was detected in splenic RNA from two cases. Thus, hepatitis B virus appears to replicate in the human spleen, although at a lower level than in the liver.Entities:
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Year: 1990 PMID: 2280024 PMCID: PMC268294 DOI: 10.1128/jcm.28.12.2850-2852.1990
Source DB: PubMed Journal: J Clin Microbiol ISSN: 0095-1137 Impact factor: 5.948