Literature DB >> 22795830

Does participation in clinical trials influence the implementation of new techniques? A look at changing techniques in breast radiotherapy in the UK.

K Venables1, Y Tsang, L Ciurlionis, C E Coles, J R Yarnold.   

Abstract

AIMS: To examine the effect of UK breast radiotherapy trials on the adoption of new radiotherapy techniques over the last 15 years.
MATERIALS AND METHODS: The data were taken from questionnaires returned to the national radiotherapy quality assurance team for each of the major trials (START, Supremo, FAST, IMPORT) with additional information sought from heads of radiotherapy physics departments where needed.
RESULTS: The peak years for the introduction of three-dimensional radiotherapy corresponded to the opening of new trials requiring these techniques. Some non-trial centres had still not implemented three-dimensional techniques for breast cancer patients at the time the most recent questionnaire was completed (2009).
CONCLUSION: Clinical trials provide the framework and impetus for introducing more accurate radiotherapy for UK women with early breast cancer.
Copyright © 2012 The Royal College of Radiologists. Published by Elsevier Ltd. All rights reserved.

Entities:  

Mesh:

Year:  2012        PMID: 22795830     DOI: 10.1016/j.clon.2012.06.010

Source DB:  PubMed          Journal:  Clin Oncol (R Coll Radiol)        ISSN: 0936-6555            Impact factor:   4.126


  8 in total

1.  Inter-departmental dosimetry audits - development of methods and lessons learned.

Authors:  David J Eaton; Steve Bolton; Russell A S Thomas; Catharine H Clark
Journal:  J Med Phys       Date:  2015 Oct-Dec

2.  Driving developments in UK oesophageal radiotherapy through the SCOPE trials.

Authors:  S Gwynne; E Higgins; A Poon King; G Radhakrishna; L Wills; S Mukherjee; Maria Hawkins; G Jones; J Staffurth; T Crosby
Journal:  Radiat Oncol       Date:  2019-02-04       Impact factor: 3.481

3.  Ten-Year Results of FAST: A Randomized Controlled Trial of 5-Fraction Whole-Breast Radiotherapy for Early Breast Cancer.

Authors:  Adrian Murray Brunt; Joanne S Haviland; Mark Sydenham; Rajiv K Agrawal; Hafiz Algurafi; Abdulla Alhasso; Peter Barrett-Lee; Peter Bliss; David Bloomfield; Joanna Bowen; Ellen Donovan; Andy Goodman; Adrian Harnett; Martin Hogg; Sri Kumar; Helen Passant; Mary Quigley; Liz Sherwin; Alan Stewart; Isabel Syndikus; Jean Tremlett; Yat Tsang; Karen Venables; Duncan Wheatley; Judith M Bliss; John R Yarnold
Journal:  J Clin Oncol       Date:  2020-07-14       Impact factor: 44.544

4.  Clinical impact of IMPORT HIGH trial (CRUK/06/003) on breast radiotherapy practices in the United Kingdom.

Authors:  Yat Tsang; Laura Ciurlionis; Anna M Kirby; Imogen Locke; Karen Venables; John R Yarnold; Jenny Titley; Judith Bliss; Charlotte E Coles
Journal:  Br J Radiol       Date:  2015-10-22       Impact factor: 3.039

5.  Evaluation of DNA extraction kits and phylogenetic diversity of the porcine gastrointestinal tract based on Illumina sequencing of two hypervariable regions.

Authors:  Katharina Burbach; Jana Seifert; Dietmar H Pieper; Amélia Camarinha-Silva
Journal:  Microbiologyopen       Date:  2015-11-05       Impact factor: 3.139

6.  Assessment of contour variability in target volumes and organs at risk in lung cancer radiotherapy.

Authors:  Yatman Tsang; Peter Hoskin; Emiliano Spezi; David Landau; Jason Lester; Elizabeth Miles; John Conibear
Journal:  Tech Innov Patient Support Radiat Oncol       Date:  2019-06-22

7.  COVID-19: A Catalyst for Change for UK Clinical Oncology.

Authors:  Charlotte Elizabeth Coles; Ananya Choudhury; Peter J Hoskin; Christopher M Jones; Ben O'Leary; Tom W Roques; Hannah Tharmalingam; Frances A P Yuille
Journal:  Int J Radiat Oncol Biol Phys       Date:  2020-10-01       Impact factor: 7.038

8.  Breast clinical target volume: HU-based glandular CTVs and ESTRO CTVs in modern and historical radiotherapy treatment planning.

Authors:  Marciana Nona Duma; Theresa Kulms; Stefan Knippen; Tobias Teichmann; Andrea Wittig
Journal:  Strahlenther Onkol       Date:  2021-09-03       Impact factor: 3.621

  8 in total

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