Literature DB >> 2279280

Studies on cardiotonic agents. II. Synthesis of novel phthalazine and 1,2,3-benzotriazine derivatives.

Y Nomoto1, H Obase, H Takai, M Teranishi, J Nakamura, K Kubo.   

Abstract

A series of phthalazine and 1,2,3-benzotriazine derivatives which have heterocyclylpiperidino groups was synthesized and tested for cardiotonic activity in anesthetized dogs. Several 6,7-dimethoxyphthalazine derivatives showed relatively potent cardiotonic activity comparable to that of amrinone.

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Year:  1990        PMID： 2279280     DOI： 10.1248/cpb.38.2179

Source DB:  PubMed          Journal:  Chem Pharm Bull (Tokyo)        ISSN： 0009-2363            Impact factor:   1.645


  5 in total

1.  Combining click-multicomponent reaction: one-pot synthesis of triazolyl methoxy-phenyl indazolo[2,1-b]phthalazine-trione derivatives.

Authors:  Peyman Salehi; David I MaGee; Minoo Dabiri; Laleh Torkian; Jordan Donahue
Journal:  Mol Divers       Date:  2011-12-11       Impact factor: 2.943

2.  Crystal structure of 13-(2-meth-oxy-phenyl)-3,4-di-hydro-2H-indazolo[1,2-b]phthalazine-1,6,11(13H)-trione.

Authors:  Abdelmalek Bouraiou; Sofiane Bouacida; Hocine Merazig; Aissa Chibani; Zouhair Bouaziz
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-07-25

3.  Crystal structure of 13-phenyl-2,3,4,13-tetra-hydro-1H-indazolo[1,2-b]phthalazine-1,6,11-trione.

Authors:  Esma Lamera; Saida Benzerka; Abdelmalek Bouraiou; Sofiane Bouacida; Hocine Merazig; Aissa Chibani; Marc Le Borgne; Zouhair Bouaziz
Journal:  Acta Crystallogr E Crystallogr Commun       Date:  2015-12-12

4.  Amino- and polyaminophthalazin-1(2H)-ones: synthesis, coordination properties, and biological activity.

Authors:  Zbigniew Malinowski; Emilia Fornal; Agata Sumara; Renata Kontek; Karol Bukowski; Beata Pasternak; Dariusz Sroczyński; Joachim Kusz; Magdalena Małecka; Monika Nowak
Journal:  Beilstein J Org Chem       Date:  2021-02-25       Impact factor: 2.883

5.  Preparation, characterization, and use of novel Cu@Fe3O4 MNPs in the synthesis of tetrahydrobenzimidazo[2,1-b]quinazolin-1(2H)-ones and 2H-indazolo[2,1-b]phthalazine-triones under solvent-free conditions.

Authors:  Lilin Jiang; Zumrat Druzhinin
Journal:  RSC Adv       Date:  2019-05-14       Impact factor: 4.036
  5 in total

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