| Literature DB >> 22790109 |
Brian D Kangas1, Jack Bergman.
Abstract
Despite the increasing sophistication and affordability of touch-sensitive technology, its use in the behavioral sciences has been limited. The present paper describes the design and empirical validation of a novel touch-sensitive operant conditioning chamber for use with unrestrained squirrel monkeys. In addition, results from a variant of a commonly employed animal model of learning, the repeated acquisition task, demonstrate the effectiveness of this chamber in programming an assay of complex behavior. Finally, results from a study with Δ(9)-tetrahydrocannabinol, the active ingredient in marijuana, show that its effects in this novel touchscreen chamber were consistent with its dose-related effects on learning using more conventional approaches. Overall, these studies indicate the touchscreen apparatus provides effective means for programming complex behavioral tasks to assess the effects of pharmacological agents on cognitive function.Entities:
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Year: 2012 PMID: 22790109 PMCID: PMC3429786 DOI: 10.1016/j.jneumeth.2012.06.028
Source DB: PubMed Journal: J Neurosci Methods ISSN: 0165-0270 Impact factor: 2.390