Literature DB >> 22784461

Multiple regression analysis of reading performance data from twin pairs with reading difficulties and nontwin siblings: the augmented model.

Sally J Wadsworth1, Richard K Olson, Erik G Willcutt, John C DeFries.   

Abstract

The augmented multiple regression model for the analysis of data from selected twin pairs was extended to facilitate analyses of data from twin pairs and nontwin siblings. Fitting this extended model to data from both selected twin pairs and siblings yields direct estimates of heritability (h2) and the difference between environmental influences shared by members of twin pairs and those of sib or twin-sib pairs (i.e., c2(t) - c2 (s)). When this model was fitted to reading performance data from 293 monozygotic and 436 dizygotic pairs selected for reading difficulties, and 291 of their nontwin siblings, h2 = .48 ± .22, p = .03, and c2 (t) - c2 (s) = .22 ± .12, p = .06. Although the test for differential shared environmental influences is only marginally significant, the results of this analysis suggest that environmental influences on reading performance that are shared by members of twin pairs (.36) may be substantially greater than those for less contemporaneous twin-sibling pairs (.14).

Entities:  

Mesh:

Year:  2012        PMID: 22784461      PMCID: PMC3398740          DOI: 10.1375/twin.15.1.116

Source DB:  PubMed          Journal:  Twin Res Hum Genet        ISSN: 1832-4274            Impact factor:   1.587


  6 in total

Review 1.  Differential genetic etiology of reading difficulties as a function of IQ: an update.

Authors:  S J Wadsworth; R K Olson; J C DeFries
Journal:  Behav Genet       Date:  2010-03-24       Impact factor: 2.805

2.  Multiple regression analysis of twin data: etiology of deviant scores versus individual differences.

Authors:  J C DeFries; D W Fulker
Journal:  Acta Genet Med Gemellol (Roma)       Date:  1988

3.  The diagnosis of twin zygosity.

Authors:  R C Nichols; W C Bilbro
Journal:  Acta Genet Stat Med       Date:  1966

4.  Multiple regression analysis of twin data.

Authors:  J C DeFries; D W Fulker
Journal:  Behav Genet       Date:  1985-09       Impact factor: 2.805

5.  DeFries-Fulker analysis of longitudinal reading performance data from twin pairs ascertained for reading difficulties and from their nontwin siblings.

Authors:  Raven L Astrom; Sally J Wadsworth; Richard K Olson; Erik G Willcutt; John C DeFries
Journal:  Behav Genet       Date:  2011-01-23       Impact factor: 2.805

6.  Genetic and environmental etiologies of reading difficulties: DeFries-Fulker analysis of reading performance data from twin pairs and their nontwin siblings.

Authors:  Raven L Astrom; Sally J Wadsworth; Richard K Olson; Erik G Willcutt; John C Defries
Journal:  Learn Individ Differ       Date:  2012-02-16
  6 in total

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