Literature DB >> 22776055

Variation in CCL3L1 copy number in rhesus macaques (Macaca mulatta).

Patrick L Taormina1, Jessica A Satkoski Trask, David G Smith, Sreetharan Kanthaswamy.   

Abstract

We used real-time quantitative PCR (qPCR) methodology to examine copy number variation (CNV) of the CCL3L1 gene among pure Indian-origin, pure Chinese-origin, and hybrid Indian-Chinese rhesus macaques (Macaca mulatta). CNV among purebred macaques fell within expected ranges, with Indian macaques having lower copy numbers than those of Chinese macaques. Compared with the purebred macaques, Indian-Chinese hybrid rhesus macaques showed much greater variance in copy number and an intermediate average copy number. Copy numbers of CCL3L1 in rhesus macaque trios (sire, dam, and offspring) were consistent with Mendelian inheritance.

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Year:  2012        PMID: 22776055      PMCID: PMC3364972     

Source DB:  PubMed          Journal:  Comp Med        ISSN: 1532-0820            Impact factor:   0.982


  39 in total

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