Literature DB >> 15322544

Genomic segmental polymorphisms in inbred mouse strains.

Jiangzhen Li1, Tao Jiang, Jian-Hua Mao, Allan Balmain, Leif Peterson, Charles Harris, Pulivarthi H Rao, Paul Havlak, Richard Gibbs, Wei-Wen Cai.   

Abstract

By analyzing genomic copy-number differences using high-resolution mouse whole-genome BAC arrays, we uncover substantial differences in regional DNA content between inbred strains of mice. The identification of these apparently common segmental polymorphisms suggests that these differences can contribute to genetic variability and pathologic susceptibility.

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Year:  2004        PMID： 15322544     DOI： 10.1038/ng1417

Source DB:  PubMed          Journal:  Nat Genet        ISSN： 1061-4036            Impact factor:   38.330


  49 in total

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