Literature DB >> 22772556

Untuning the tumor metabolic machine: HIF-α: pro- and antitumorigenic?

Regina M Young1, M Celeste Simon.   

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Year:  2012        PMID: 22772556      PMCID: PMC3728670          DOI: 10.1038/nm.2865

Source DB:  PubMed          Journal:  Nat Med        ISSN: 1078-8956            Impact factor:   53.440


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  12 in total

Review 1.  Cellular metabolism and disease: what do metabolic outliers teach us?

Authors:  Ralph J DeBerardinis; Craig B Thompson
Journal:  Cell       Date:  2012-03-16       Impact factor: 41.582

2.  IDH mutation impairs histone demethylation and results in a block to cell differentiation.

Authors:  Chao Lu; Patrick S Ward; Gurpreet S Kapoor; Dan Rohle; Sevin Turcan; Omar Abdel-Wahab; Christopher R Edwards; Raya Khanin; Maria E Figueroa; Ari Melnick; Kathryn E Wellen; Donald M O'Rourke; Shelley L Berger; Timothy A Chan; Ross L Levine; Ingo K Mellinghoff; Craig B Thompson
Journal:  Nature       Date:  2012-02-15       Impact factor: 49.962

3.  HIF-2alpha deletion promotes Kras-driven lung tumor development.

Authors:  Jolly Mazumdar; Michele M Hickey; Dhruv K Pant; Amy C Durham; Alejandro Sweet-Cordero; Anil Vachani; Tyler Jacks; Lewis A Chodosh; Joseph L Kissil; M Celeste Simon; Brian Keith
Journal:  Proc Natl Acad Sci U S A       Date:  2010-07-21       Impact factor: 11.205

4.  Cancer-associated IDH1 mutations produce 2-hydroxyglutarate.

Authors:  Lenny Dang; David W White; Stefan Gross; Bryson D Bennett; Mark A Bittinger; Edward M Driggers; Valeria R Fantin; Hyun Gyung Jang; Shengfang Jin; Marie C Keenan; Kevin M Marks; Robert M Prins; Patrick S Ward; Katharine E Yen; Linda M Liau; Joshua D Rabinowitz; Lewis C Cantley; Craig B Thompson; Matthew G Vander Heiden; Shinsan M Su
Journal:  Nature       Date:  2009-12-10       Impact factor: 49.962

5.  Hypoxia-inducible factors regulate tumorigenic capacity of glioma stem cells.

Authors:  Zhizhong Li; Shideng Bao; Qiulian Wu; Hui Wang; Christine Eyler; Sith Sathornsumetee; Qing Shi; Yiting Cao; Justin Lathia; Roger E McLendon; Anita B Hjelmeland; Jeremy N Rich
Journal:  Cancer Cell       Date:  2009-06-02       Impact factor: 31.743

6.  Genetic and functional studies implicate HIF1α as a 14q kidney cancer suppressor gene.

Authors:  Chuan Shen; Rameen Beroukhim; Steven E Schumacher; Jing Zhou; Michelle Chang; Sabina Signoretti; William G Kaelin
Journal:  Cancer Discov       Date:  2011-06-07       Impact factor: 39.397

7.  Genome-wide association study of renal cell carcinoma identifies two susceptibility loci on 2p21 and 11q13.3.

Authors:  Mark P Purdue; Mattias Johansson; Diana Zelenika; Jorge R Toro; Ghislaine Scelo; Lee E Moore; Egor Prokhortchouk; Xifeng Wu; Lambertus A Kiemeney; Valerie Gaborieau; Kevin B Jacobs; Wong-Ho Chow; David Zaridze; Vsevolod Matveev; Jan Lubinski; Joanna Trubicka; Neonila Szeszenia-Dabrowska; Jolanta Lissowska; Péter Rudnai; Eleonora Fabianova; Alexandru Bucur; Vladimir Bencko; Lenka Foretova; Vladimir Janout; Paolo Boffetta; Joanne S Colt; Faith G Davis; Kendra L Schwartz; Rosamonde E Banks; Peter J Selby; Patricia Harnden; Christine D Berg; Ann W Hsing; Robert L Grubb; Heiner Boeing; Paolo Vineis; Françoise Clavel-Chapelon; Domenico Palli; Rosario Tumino; Vittorio Krogh; Salvatore Panico; Eric J Duell; José Ramón Quirós; Maria-José Sanchez; Carmen Navarro; Eva Ardanaz; Miren Dorronsoro; Kay-Tee Khaw; Naomi E Allen; H Bas Bueno-de-Mesquita; Petra H M Peeters; Dimitrios Trichopoulos; Jakob Linseisen; Börje Ljungberg; Kim Overvad; Anne Tjønneland; Isabelle Romieu; Elio Riboli; Anush Mukeria; Oxana Shangina; Victoria L Stevens; Michael J Thun; W Ryan Diver; Susan M Gapstur; Paul D Pharoah; Douglas F Easton; Demetrius Albanes; Stephanie J Weinstein; Jarmo Virtamo; Lars Vatten; Kristian Hveem; Inger Njølstad; Grethe S Tell; Camilla Stoltenberg; Rajiv Kumar; Kvetoslava Koppova; Olivier Cussenot; Simone Benhamou; Egbert Oosterwijk; Sita H Vermeulen; Katja K H Aben; Saskia L van der Marel; Yuanqing Ye; Christopher G Wood; Xia Pu; Alexander M Mazur; Eugenia S Boulygina; Nikolai N Chekanov; Mario Foglio; Doris Lechner; Ivo Gut; Simon Heath; Hélène Blanche; Amy Hutchinson; Gilles Thomas; Zhaoming Wang; Meredith Yeager; Joseph F Fraumeni; Konstantin G Skryabin; James D McKay; Nathaniel Rothman; Stephen J Chanock; Mark Lathrop; Paul Brennan
Journal:  Nat Genet       Date:  2010-12-05       Impact factor: 38.330

Review 8.  HIF1α and HIF2α: sibling rivalry in hypoxic tumour growth and progression.

Authors:  Brian Keith; Randall S Johnson; M Celeste Simon
Journal:  Nat Rev Cancer       Date:  2011-12-15       Impact factor: 60.716

9.  Transformation by the (R)-enantiomer of 2-hydroxyglutarate linked to EGLN activation.

Authors:  Peppi Koivunen; Sungwoo Lee; Christopher G Duncan; Giselle Lopez; Gang Lu; Shakti Ramkissoon; Julie A Losman; Päivi Joensuu; Ulrich Bergmann; Stefan Gross; Jeremy Travins; Samuel Weiss; Ryan Looper; Keith L Ligon; Roel G W Verhaak; Hai Yan; William G Kaelin
Journal:  Nature       Date:  2012-02-15       Impact factor: 49.962

10.  IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype.

Authors:  Sevin Turcan; Daniel Rohle; Anuj Goenka; Logan A Walsh; Fang Fang; Emrullah Yilmaz; Carl Campos; Armida W M Fabius; Chao Lu; Patrick S Ward; Craig B Thompson; Andrew Kaufman; Olga Guryanova; Ross Levine; Adriana Heguy; Agnes Viale; Luc G T Morris; Jason T Huse; Ingo K Mellinghoff; Timothy A Chan
Journal:  Nature       Date:  2012-02-15       Impact factor: 69.504

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  11 in total

Review 1.  Mitochondrial retrograde signaling at the crossroads of tumor bioenergetics, genetics and epigenetics.

Authors:  Manti Guha; Narayan G Avadhani
Journal:  Mitochondrion       Date:  2013-09-01       Impact factor: 4.160

Review 2.  Hypoxia-inducible factor signaling in pheochromocytoma: turning the rudder in the right direction.

Authors:  Ivana Jochmanová; Chunzhang Yang; Zhengping Zhuang; Karel Pacak
Journal:  J Natl Cancer Inst       Date:  2013-08-12       Impact factor: 13.506

Review 3.  Oncometabolites: linking altered metabolism with cancer.

Authors:  Ming Yang; Tomoyoshi Soga; Patrick J Pollard
Journal:  J Clin Invest       Date:  2013-09-03       Impact factor: 14.808

4.  Intermittent induction of HIF-1α produces lasting effects on malignant progression independent of its continued expression.

Authors:  Hyunsung Choi; David L Gillespie; Shauna Berg; Christopher Rice; Sandrine Couldwell; Jie Gu; Howard Colman; Randy L Jensen; L Eric Huang
Journal:  PLoS One       Date:  2015-04-20       Impact factor: 3.240

5.  Mutation of IDH1 aggravates the fatty acid‑induced oxidative stress in HCT116 cells by affecting the mitochondrial respiratory chain.

Authors:  Sheng Li; Chao Sun; Yu Gu; Xing Gao; Yuanlin Zhao; Yuan Yuan; Feng Zhang; Peizhen Hu; Weihua Liang; Kaiyu Cao; Jin Zhang; Zhe Wang; Jing Ye
Journal:  Mol Med Rep       Date:  2019-01-28       Impact factor: 2.952

6.  Regulation of glucose metabolism by p62/SQSTM1 through HIF1α.

Authors:  Ke Chen; Jin Zeng; Haibing Xiao; Chunhua Huang; Junhui Hu; Weimin Yao; Gan Yu; Wei Xiao; Hua Xu; Zhangqun Ye
Journal:  J Cell Sci       Date:  2016-01-07       Impact factor: 5.285

7.  miR-490-5p suppresses tumour growth in renal cell carcinoma through targeting PIK3CA.

Authors:  Ke Chen; Jin Zeng; Kun Tang; Haibing Xiao; Junhui Hu; Chunhua Huang; Weimin Yao; Gan Yu; Wei Xiao; Wei Guan; Xiaolin Guo; Hua Xu; Zhangqun Ye
Journal:  Biol Cell       Date:  2015-12-22       Impact factor: 4.458

8.  MicroRNA-101 targets von Hippel-Lindau tumor suppressor (VHL) to induce HIF1α mediated apoptosis and cell cycle arrest in normoxia condition.

Authors:  Ning Liu; Wu-Yan Xia; Shan-Shan Liu; Hai-Yan Chen; Lei Sun; Meng-Yao Liu; Lin-Feng Li; Hong-Min Lu; Yu-Jie Fu; Pei Wang; Hailong Wu; Jian-Xin Gao
Journal:  Sci Rep       Date:  2016-02-04       Impact factor: 4.379

Review 9.  Hypoxia Signaling and Circadian Disruption in and by Pheochromocytoma.

Authors:  Mouna Tabebi; Peter Söderkvist; Lasse D Jensen
Journal:  Front Endocrinol (Lausanne)       Date:  2018-10-16       Impact factor: 5.555

10.  The HIF1α/HIF2α-miR210-3p network regulates glioblastoma cell proliferation, dedifferentiation and chemoresistance through EGF under hypoxic conditions.

Authors:  Pan Wang; Qian Yan; Bin Liao; Lu Zhao; Shuanglong Xiong; Junwei Wang; Dewei Zou; Jinyu Pan; Liangqi Wu; Yangmin Deng; Nan Wu; Sheng Gong
Journal:  Cell Death Dis       Date:  2020-11-18       Impact factor: 8.469

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