Literature DB >> 22772555

Untuning the tumor metabolic machine: Targeting cancer metabolism: a bedside lesson.

Kıvanç Birsoy1, David M Sabatini, Richard Possemato.   

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Year:  2012        PMID： 22772555     DOI： 10.1038/nm.2870

Source DB:  PubMed          Journal:  Nat Med        ISSN： 1078-8956            Impact factor:   53.440


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  21 in total

1.  Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferation.

Authors:  Mohit Jain; Roland Nilsson; Sonia Sharma; Nikhil Madhusudhan; Toshimori Kitami; Amanda L Souza; Ran Kafri; Marc W Kirschner; Clary B Clish; Vamsi K Mootha
Journal:  Science       Date:  2012-05-25       Impact factor: 47.728

2.  Prevention of pancreatic cancer induction in hamsters by metformin.

Authors:  M B Schneider; H Matsuzaki; J Haorah; A Ulrich; J Standop; X Z Ding; T E Adrian; P M Pour
Journal:  Gastroenterology       Date:  2001-04       Impact factor: 22.682

3.  Analysis of tumor metabolism reveals mitochondrial glucose oxidation in genetically diverse human glioblastomas in the mouse brain in vivo.

Authors:  Isaac Marin-Valencia; Chendong Yang; Tomoyuki Mashimo; Steve Cho; Hyeonman Baek; Xiao-Li Yang; Kartik N Rajagopalan; Melissa Maddie; Vamsidhara Vemireddy; Zhenze Zhao; Ling Cai; Levi Good; Benjamin P Tu; Kimmo J Hatanpaa; Bruce E Mickey; José M Matés; Juan M Pascual; Elizabeth A Maher; Craig R Malloy; Ralph J Deberardinis; Robert M Bachoo
Journal:  Cell Metab       Date:  2012-06-06       Impact factor: 27.287

4.  Metformin use is associated with better survival of diabetic patients with pancreatic cancer.

Authors:  Navid Sadeghi; James L Abbruzzese; Sai-Ching J Yeung; Manal Hassan; Donghui Li
Journal:  Clin Cancer Res       Date:  2012-03-31       Impact factor: 12.531

Review 5.  IDH mutations in glioma and acute myeloid leukemia.

Authors:  Lenny Dang; Shengfang Jin; Shinsan M Su
Journal:  Trends Mol Med       Date:  2010-08-05       Impact factor: 11.951

Review 6.  Metformin and cancer risk in diabetic patients: a systematic review and meta-analysis.

Authors:  Andrea Decensi; Matteo Puntoni; Pamela Goodwin; Massimiliano Cazzaniga; Alessandra Gennari; Bernardo Bonanni; Sara Gandini
Journal:  Cancer Prev Res (Phila)       Date:  2010-10-12

7.  Increased FDG uptake in breast cancer is associated with prognostic factors.

Authors:  Yasemin Sanli; Serkan Kuyumcu; Zeynep Gozde Ozkan; Göknur Işik; Hasan Karanlik; Burcu Guzelbey; Cuneyt Turkmen; Sevda Ozel; Ekrem Yavuz; Ayse Mudun
Journal:  Ann Nucl Med       Date:  2012-02-24       Impact factor: 2.668

8.  Role of AMP-activated protein kinase in mechanism of metformin action.

Authors:  G Zhou; R Myers; Y Li; Y Chen; X Shen; J Fenyk-Melody; M Wu; J Ventre; T Doebber; N Fujii; N Musi; M F Hirshman; L J Goodyear; D E Moller
Journal:  J Clin Invest       Date:  2001-10       Impact factor: 14.808

Review 9.  The biology of cancer: metabolic reprogramming fuels cell growth and proliferation.

Authors:  Ralph J DeBerardinis; Julian J Lum; Georgia Hatzivassiliou; Craig B Thompson
Journal:  Cell Metab       Date:  2008-01       Impact factor: 27.287

10.  Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.

Authors:  Richard Possemato; Kevin M Marks; Yoav D Shaul; Michael E Pacold; Dohoon Kim; Kıvanç Birsoy; Shalini Sethumadhavan; Hin-Koon Woo; Hyun G Jang; Abhishek K Jha; Walter W Chen; Francesca G Barrett; Nicolas Stransky; Zhi-Yang Tsun; Glenn S Cowley; Jordi Barretina; Nada Y Kalaany; Peggy P Hsu; Kathleen Ottina; Albert M Chan; Bingbing Yuan; Levi A Garraway; David E Root; Mari Mino-Kenudson; Elena F Brachtel; Edward M Driggers; David M Sabatini
Journal:  Nature       Date:  2011-08-18       Impact factor: 49.962
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  32 in total

Review 1.  Mitochondrial Metabolism as a Target for Cancer Therapy.

Authors:  Karthik Vasan; Marie Werner; Navdeep S Chandel
Journal:  Cell Metab       Date:  2020-07-14       Impact factor: 27.287

2.  Environment Dictates Dependence on Mitochondrial Complex I for NAD+ and Aspartate Production and Determines Cancer Cell Sensitivity to Metformin.

Authors:  Dan Y Gui; Lucas B Sullivan; Alba Luengo; Aaron M Hosios; Lauren N Bush; Nadege Gitego; Shawn M Davidson; Elizaveta Freinkman; Craig J Thomas; Matthew G Vander Heiden
Journal:  Cell Metab       Date:  2016-10-13       Impact factor: 27.287

3.  Palliative treatment efficacy of glucose inhibition combined with chemotherapy for non-small cell lung cancer with widespread bone and brain metastases: A case report.

Authors:  Yongping Liu; Yaping Zhang; Xibao Mao; Qiufeng Qi; Ming Zhu; Changsong Zhang; Xuefeng Pan; Yang Ling
Journal:  Biomed Rep       Date:  2017-10-24

Review 4.  Serine, glycine and one-carbon units: cancer metabolism in full circle.

Authors:  Jason W Locasale
Journal:  Nat Rev Cancer       Date:  2013-07-04       Impact factor: 60.716

Review 5.  Targeting mitochondria metabolism for cancer therapy.

Authors:  Samuel E Weinberg; Navdeep S Chandel
Journal:  Nat Chem Biol       Date:  2015-01       Impact factor: 15.040

6.  Metabolic signature identifies novel targets for drug resistance in multiple myeloma.

Authors:  Patricia Maiso; Daisy Huynh; Michele Moschetta; Antonio Sacco; Yosra Aljawai; Yuji Mishima; John M Asara; Aldo M Roccaro; Alec C Kimmelman; Irene M Ghobrial
Journal:  Cancer Res       Date:  2015-03-13       Impact factor: 12.701

Review 7.  Targeting mitochondria in cancer: current concepts and immunotherapy approaches.

Authors:  Sergey Pustylnikov; Francesca Costabile; Silvia Beghi; Andrea Facciabene
Journal:  Transl Res       Date:  2018-07-31       Impact factor: 7.012

8.  LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin.

Authors:  David B Shackelford; Evan Abt; Laurie Gerken; Debbie S Vasquez; Atsuko Seki; Mathias Leblanc; Liu Wei; Michael C Fishbein; Johannes Czernin; Paul S Mischel; Reuben J Shaw
Journal:  Cancer Cell       Date:  2013-01-24       Impact factor: 31.743

9.  Glucose-deprivation increases thyroid cancer cells sensitivity to metformin.

Authors:  Athanasios Bikas; Kirk Jensen; Aneeta Patel; John Costello; Dennis McDaniel; Joanna Klubo-Gwiezdzinska; Olexander Larin; Victoria Hoperia; Kenneth D Burman; Lisa Boyle; Leonard Wartofsky; Vasyl Vasko
Journal:  Endocr Relat Cancer       Date:  2015-09-11       Impact factor: 5.678

10.  Mitochondria-Targeted Analogues of Metformin Exhibit Enhanced Antiproliferative and Radiosensitizing Effects in Pancreatic Cancer Cells.

Authors:  Gang Cheng; Jacek Zielonka; Olivier Ouari; Marcos Lopez; Donna McAllister; Kathleen Boyle; Christy S Barrios; James J Weber; Bryon D Johnson; Micael Hardy; Michael B Dwinell; Balaraman Kalyanaraman
Journal:  Cancer Res       Date:  2016-05-23       Impact factor: 12.701
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