Kristin Klein1, Alexa Nardelli, Tania Stafinski. 1. Faculty of Medicine and Dentistry, School of Public Health, University of Alberta, Edmonton, Alberta, Canada. kristin.klein@ualberta.ca
Abstract
OBJECTIVE: To examine the safety and effectiveness of fully implantable middle ear devices in the treatment of hearing loss. DATA SOURCES: MEDLINE, EMBASE, The Cochrane Library, Web of Science, CINAHL, PsycINFO, and the Centre for Reviews and Dissemination were searched without date or language limits. STUDY SELECTION: Titles and abstracts of 7,700 citations were screened, and 30 articles were selected for full review, of which, 7 articles on the Esteem and 13 on the Carina met the study's eligibility criteria. DATA EXTRACTION: Information was extracted using a pretested data abstraction form, and study quality was assessed using the Oxford Centre for Evidence-Based Medicine Levels of Evidence. DATA SYNTHESIS: Because of heterogeneity across studies, meta-analysis was not performed, and comparisons were made by structured review. CONCLUSION: The majority of studies were quasi-experimental, prepost comparisons of aided and unaided conditions. Complication rates with the Esteem were higher than with the Carina, and most commonly included taste disturbance. However, device failure was common with the Carina, predominately related to charging difficulties. For both devices, clinically significant improvements in functional gain, speech reception, and speech recognition over the unaided condition were found. In studies comparing the Esteem or Carina to hearing aids, findings were mixed. Although improvements in functional gain were similar to those for hearing aids, speech recognition and quality of life were greater with the implants. Despite limited evidence, these devices seem to offer a relatively safe and effective treatment option, particularly for patients who are medically unable to wear conventional hearing aids.
OBJECTIVE: To examine the safety and effectiveness of fully implantable middle ear devices in the treatment of hearing loss. DATA SOURCES: MEDLINE, EMBASE, The Cochrane Library, Web of Science, CINAHL, PsycINFO, and the Centre for Reviews and Dissemination were searched without date or language limits. STUDY SELECTION: Titles and abstracts of 7,700 citations were screened, and 30 articles were selected for full review, of which, 7 articles on the Esteem and 13 on the Carina met the study's eligibility criteria. DATA EXTRACTION: Information was extracted using a pretested data abstraction form, and study quality was assessed using the Oxford Centre for Evidence-Based Medicine Levels of Evidence. DATA SYNTHESIS: Because of heterogeneity across studies, meta-analysis was not performed, and comparisons were made by structured review. CONCLUSION: The majority of studies were quasi-experimental, prepost comparisons of aided and unaided conditions. Complication rates with the Esteem were higher than with the Carina, and most commonly included taste disturbance. However, device failure was common with the Carina, predominately related to charging difficulties. For both devices, clinically significant improvements in functional gain, speech reception, and speech recognition over the unaided condition were found. In studies comparing the Esteem or Carina to hearing aids, findings were mixed. Although improvements in functional gain were similar to those for hearing aids, speech recognition and quality of life were greater with the implants. Despite limited evidence, these devices seem to offer a relatively safe and effective treatment option, particularly for patients who are medically unable to wear conventional hearing aids.
Authors: Hannes Maier; Uwe Baumann; Wolf-Dieter Baumgartner; Dirk Beutner; Marco D Caversaccio; Thomas Keintzel; Martin Kompis; Thomas Lenarz; Astrid Magele; Torsten Mewes; Alexander Müller; Tobias Rader; Torsten Rahne; Sebastian P Schraven; Burkard Schwab; Georg Mathias Sprinzl; Bernd Strauchmann; Ingo Todt; Thomas Wesarg; Barbara Wollenberg; Stefan K Plontke Journal: Audiol Neurootol Date: 2018-09-07 Impact factor: 1.854
Authors: Janaina Oliveira Bentivi Pulcherio; Aline Gomes Bittencourt; Patrick Rademaker Burke; Rafael da Costa Monsanto; Rubens de Brito; Robinson Koji Tsuji; Ricardo Ferreira Bento Journal: PLoS One Date: 2014-10-17 Impact factor: 3.240
Authors: Aline Gomes Bittencourt; Patrick Rademaker Burke; Isabela de Souza Jardim; Rubens de Brito; Robinson Koji Tsuji; Anna Carolina de Oliveira Fonseca; Ricardo Ferreira Bento Journal: Int Arch Otorhinolaryngol Date: 2014-04-09