| Literature DB >> 22771992 |
Albert Canals1, Alexandre G Blanco, Miquel Coll.
Abstract
Transcription factors modulate gene expression by distinct, barely understood mechanisms. The crystal structure of a bacterial transcription subcomplex comprising the effector domain of factor PhoB, its target DNA and the σ4 domain of the RNA polymerase σ70 subunit supports the notion that a stronger grip on the promoter-factor complex results in an enhanced RNAP architecture.Mesh:
Substances:
Year: 2012 PMID: 22771992 PMCID: PMC3654763 DOI: 10.4161/trns.20444
Source DB: PubMed Journal: Transcription ISSN: 2154-1272