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Literature DB >> 22771946

p53 and metabolism: old player in a new game.

Nirmalya Sen¹, Yatendra Kumar Satija, Sanjeev Das.

Abstract

Metabolic reprogramming is an integral part of tumorigenesis. Tumor suppressor p53 is a well studied transcription factor intimately linked with the control of cell cycle progression and apoptosis. Here, we discuss the emerging role of p53 in the transcriptional regulation of metabolism. This activity is a key component of p53 tumor suppression function.

Entities: Disease Gene

Mesh：

Substances：

Year: 2012 PMID： 22771946 PMCID： PMC3616081 DOI： 10.4161/trns.20094

Source DB: PubMed Journal: Transcription ISSN： 2154-1272

38 in total

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Review 5. Metabostemness: a new cancer hallmark.

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Review 7. Cross-talk between HIF and p53 as mediators of molecular responses to physiological and genotoxic stresses.

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Review 8. Metabostemness in cancer: Linking metaboloepigenetics and mitophagy in remodeling cancer stem cells.

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8 in total