Literature DB >> 26106139

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression.

Rita Nahta1, Fahd Al-Mulla2, Rabeah Al-Temaimi2, Amedeo Amedei3, Rafaela Andrade-Vieira4, Sarah N Bay5, Dustin G Brown6, Gloria M Calaf7, Robert C Castellino8, Karine A Cohen-Solal9, Annamaria Colacci10, Nichola Cruickshanks11, Paul Dent11, Riccardo Di Fiore12, Stefano Forte13, Gary S Goldberg14, Roslida A Hamid15, Harini Krishnan14, Dale W Laird16, Ahmed Lasfar17, Paola A Marignani4, Lorenzo Memeo13, Chiara Mondello18, Christian C Naus19, Richard Ponce-Cusi20, Jayadev Raju21, Debasish Roy22, Rabindra Roy23, Elizabeth P Ryan6, Hosni K Salem24, A Ivana Scovassi18, Neetu Singh25, Monica Vaccari10, Renza Vento26, Jan Vondráček27, Mark Wade28, Jordan Woodrick23, William H Bisson29.   

Abstract

As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
© The Author 2015. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oup.com.

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Year:  2015        PMID： 26106139      PMCID： PMC4565608          DOI： 10.1093/carcin/bgv028

Source DB:  PubMed          Journal:  Carcinogenesis        ISSN： 0143-3334            Impact factor:   4.944


  254 in total

1.  Structure of the human Mdmx protein bound to the p53 tumor suppressor transactivation domain.

Authors:  Grzegorz M Popowicz; Anna Czarna; Tad A Holak
Journal:  Cell Cycle       Date:  2008-05-27       Impact factor: 4.534

2.  Altered function, localization and phosphorylation of gap junctions in rat liver epithelial, IAR 20, cells after treatment with PCBs or TCDD.

Authors:  Y Bager; M C Lindebro; P Martel; C Chaumontet; L Wärngård
Journal:  Environ Toxicol Pharmacol       Date:  1997-09       Impact factor: 4.860

Review 3.  DNA damage checkpoints in stem cells, ageing and cancer.

Authors:  Tobias Sperka; Jianwei Wang; K Lenhard Rudolph
Journal:  Nat Rev Mol Cell Biol       Date:  2012-09       Impact factor: 94.444

Review 4.  Involvement of RB gene family in tumor angiogenesis.

Authors:  C Gabellini; D Del Bufalo; G Zupi
Journal:  Oncogene       Date:  2006-08-28       Impact factor: 9.867

5.  The Lkb1 metabolic sensor maintains haematopoietic stem cell survival.

Authors:  Sushma Gurumurthy; Stephanie Z Xie; Brinda Alagesan; Judith Kim; Rushdia Z Yusuf; Borja Saez; Alexandros Tzatsos; Fatih Ozsolak; Patrice Milos; Francesco Ferrari; Peter J Park; Orian S Shirihai; David T Scadden; Nabeel Bardeesy
Journal:  Nature       Date:  2010-12-02       Impact factor: 49.962

6.  Exploring the relationship between the inhibition of gap junctional intercellular communication and other biological phenomena.

Authors:  H S Rosenkranz; N Pollack; A R Cunningham
Journal:  Carcinogenesis       Date:  2000-05       Impact factor: 4.944

7.  Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model.

Authors:  E Decrock; E De Vuyst; M Vinken; M Van Moorhem; K Vranckx; N Wang; L Van Laeken; M De Bock; K D'Herde; C P Lai; V Rogiers; W H Evans; C C Naus; L Leybaert
Journal:  Cell Death Differ       Date:  2008-09-26       Impact factor: 15.828

8.  Regulation of miRNA expression by Src and contact normalization: effects on nonanchored cell growth and migration.

Authors:  X Li; Y Shen; H Ichikawa; T Antes; G S Goldberg
Journal:  Oncogene       Date:  2009-09-21       Impact factor: 9.867

9.  Inhibitory effect of pentachlorophenol on gap junctional intercellular communication in rat liver epithelial cells in vitro.

Authors:  K Sai; B L Upham; K S Kang; R Hasegawa; T Inoue; J E Trosko
Journal:  Cancer Lett       Date:  1998-08-14       Impact factor: 8.679

Review 10.  The aryl hydrocarbon receptor, more than a xenobiotic-interacting protein.

Authors:  Robert Barouki; Xavier Coumoul; Pedro M Fernandez-Salguero
Journal:  FEBS Lett       Date:  2007-03-30       Impact factor: 4.124
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  18 in total

1.  Effect of estrogen-active compounds on the expression of RACK1 and immunological implications.

Authors:  Erica Buoso; Mirco Masi; Valentina Galbiati; Ambra Maddalon; Martina Iulini; Maša Kenda; Marija Sollner Dolenc; Marina Marinovich; Marco Racchi; Emanuela Corsini
Journal:  Arch Toxicol       Date:  2020-04-23       Impact factor: 5.153

2.  Airborne PAHs inhibit gap junctional intercellular communication and activate MAPKs in human bronchial epithelial cell line.

Authors:  Ondřej Brózman; Jiří Novák; Alison K Bauer; Pavel Babica
Journal:  Environ Toxicol Pharmacol       Date:  2020-05-31       Impact factor: 4.860

3.  Early Mechanistic Events Induced by Low Molecular Weight Polycyclic Aromatic Hydrocarbons in Mouse Lung Epithelial Cells: A Role for Eicosanoid Signaling.

Authors:  Katelyn J Siegrist; DeeDee Romo; Brad L Upham; Michael Armstrong; Kevin Quinn; Lauren Vanderlinden; Ross S Osgood; Kalpana Velmurugan; Marc Elie; Jonathan Manke; Dominik Reinhold; Nichole Reisdorph; Laura Saba; Alison K Bauer
Journal:  Toxicol Sci       Date:  2019-05-01       Impact factor: 4.849

Review 4.  Integration of Epigenetic Mechanisms into Non-Genotoxic Carcinogenicity Hazard Assessment: Focus on DNA Methylation and Histone Modifications.

Authors:  Daniel Desaulniers; Paule Vasseur; Abigail Jacobs; M Cecilia Aguila; Norman Ertych; Miriam N Jacobs
Journal:  Int J Mol Sci       Date:  2021-10-11       Impact factor: 5.923

5.  Ceramide/protein phosphatase 2A axis is engaged in gap junction impairment elicited by PCB153 in liver stem-like progenitor cells.

Authors:  Roberta Squecco; Federica Pierucci; Eglantina Idrizaj; Alessia Frati; Elena Lenci; Catia Vicenti; Maria Chiara Iachini; Maria Martinesi; Rachele Garella; Maria Caterina Baccari; Fabio Francini; Elisabetta Meacci
Journal:  Mol Cell Biochem       Date:  2021-04-10       Impact factor: 3.396

Review 6.  Environmental Ligands of the Aryl Hydrocarbon Receptor and Their Effects in Models of Adult Liver Progenitor Cells.

Authors:  Jan Vondráček; Miroslav Machala
Journal:  Stem Cells Int       Date:  2016-05-04       Impact factor: 5.443

Review 7.  Predicting disease onset in clinically healthy people.

Authors:  Harold I Zeliger
Journal:  Interdiscip Toxicol       Date:  2017-05-17

8.  Natural Compounds As Modulators of Non-apoptotic Cell Death in Cancer Cells.

Authors:  Luis Miguel Guamán-Ortiz; Maria Isabel Ramirez Orellana; Edward A Ratovitski
Journal:  Curr Genomics       Date:  2017-04       Impact factor: 2.236

9.  The Key Characteristics of Carcinogens: Relationship to the Hallmarks of Cancer, Relevant Biomarkers, and Assays to Measure Them.

Authors:  Martyn T Smith; Kathryn Z Guyton; Nicole Kleinstreuer; Alexandre Borrel; Andres Cardenas; Weihsueh A Chiu; Dean W Felsher; Catherine F Gibbons; William H Goodson; Keith A Houck; Agnes B Kane; Michele A La Merrill; Herve Lebrec; Leroy Lowe; Cliona M McHale; Sheroy Minocherhomji; Linda Rieswijk; Martha S Sandy; Hideko Sone; Amy Wang; Luoping Zhang; Lauren Zeise; Mark Fielden
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2020-03-09       Impact factor: 4.254

10.  Low-Dose Mixture Hypothesis of Carcinogenesis Workshop: Scientific Underpinnings and Research Recommendations.

Authors:  Mark F Miller; William H Goodson; Masoud H Manjili; Nicole Kleinstreuer; William H Bisson; Leroy Lowe
Journal:  Environ Health Perspect       Date:  2016-08-12       Impact factor: 9.031
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