| Literature DB >> 22771540 |
Covadonga Huidobro1, Agustin F Fernandez, Mario F Fraga.
Abstract
Growth and development of higher organisms are regulated by the orchestrated change of epigenetic marks over time. In addition, there is also an epigenetic variation without any apparent role in development that is thought to be the result of the stochastic accumulation of epigenetic errors. The process depends on genetic and environmental factors and, when it takes place in adult stem cells, it could play an important role in aging, although the underlying molecular mechanisms are still largely unknown.Mesh：
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Year: 2012 PMID： 22771540 DOI： 10.1016/j.mam.2012.06.006
Source DB: PubMed Journal: Mol Aspects Med ISSN： 0098-2997