OBJECTIVE: Oral malignant melanoma (OMM) is a rare tumor of the oral cavity with very poor prognosis despite the implementation of an aggressive treatment. This paper aims to shed some light on current evidence for management of OMM. STUDY DESIGN: We report 2 cases of OMM treated at our institute and a review of the literature in an endeavor to establish current understanding on various aspects of OMM. RESULTS: Both patients in our study are showing good local control with aggressive multimodal treatment. Long-term follow-up is needed to rule out distant metastasis. CONCLUSIONS: Because late diagnosis and advanced disease at the time of diagnosis are the only sure predictors of outcome, thorough clinical and pathologic workup of any suspected melanotic lesion should be carried out to diagnose OMM. Early diagnosis and aggressive multimodal treatment are the only means available to surgeons to provide better outcome to patients with OMM.
OBJECTIVE: Oral malignant melanoma (OMM) is a rare tumor of the oral cavity with very poor prognosis despite the implementation of an aggressive treatment. This paper aims to shed some light on current evidence for management of OMM. STUDY DESIGN: We report 2 cases of OMM treated at our institute and a review of the literature in an endeavor to establish current understanding on various aspects of OMM. RESULTS: Both patients in our study are showing good local control with aggressive multimodal treatment. Long-term follow-up is needed to rule out distant metastasis. CONCLUSIONS: Because late diagnosis and advanced disease at the time of diagnosis are the only sure predictors of outcome, thorough clinical and pathologic workup of any suspected melanotic lesion should be carried out to diagnose OMM. Early diagnosis and aggressive multimodal treatment are the only means available to surgeons to provide better outcome to patients with OMM.
Authors: Luiz Fernando Barbosa de Paulo; João Paulo Silva Servato; Roberta Rezende Rosa; Maiolino Thomaz Fonseca Oliveira; Paulo Rogério de Faria; Sindeval José da Silva; Sergio Vitorino Cardoso; Adriano Mota Loyola Journal: Oral Maxillofac Surg Date: 2015-05-03
Authors: Johannes Laimer; Raphael Henn; Tom Helten; Susanne Sprung; Bettina Zelger; Bernhard Zelger; René Steiner; Dagmar Schnabl; Vincent Offermanns; Emanuel Bruckmoser; Christian W Huck Journal: PLoS One Date: 2018-11-06 Impact factor: 3.240