Literature DB >> 22768903

An analysis of the "Effect of Olibra: a 12-week randomized control trial and a review of earlier studies".

Martina Heer1.   

Abstract

Nutrients affect hunger and satiety. However, food structure, in particular that of emulsions, may also affect the body's satiety mechanisms. Olibra™ is a fat emulsion, a mixture of fractionated palm oil and fractionated oat oil manufactured by Lipid Technologies Provider AB, Sweden, which affects hunger sensation. However, up to now, no data have shown convincingly that reduced appetite or hunger sensations induced by Olibra lead, in the long run, to a significant and clinically relevant reduction in body mass. To clearly demonstrate a cause-and-effect relationship of Olibra to weight loss, it seems that longer studies with strict control of energy intake and nutrient composition, as well as control of energy expenditure by exercise, are needed.
© 2012 Diabetes Technology Society.

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Year:  2012        PMID: 22768903      PMCID: PMC3440034          DOI: 10.1177/193229681200600327

Source DB:  PubMed          Journal:  J Diabetes Sci Technol        ISSN: 1932-2968


  11 in total

Review 1.  Gastrointestinal satiety signals I. An overview of gastrointestinal signals that influence food intake.

Authors:  Stephen C Woods
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2004-01       Impact factor: 4.052

2.  No appetite efficacy of a commercial structured lipid emulsion in minimally processed drinks.

Authors:  H J Smit; E Keenan; E M R Kovacs; S A Wiseman; D J Mela; P J Rogers
Journal:  Int J Obes (Lond)       Date:  2011-11-29       Impact factor: 5.095

3.  No efficacy of processed Fabuless (Olibra) in suppressing appetite or food intake.

Authors:  H J Smit; E Keenan; E M R Kovacs; S A Wiseman; H P F Peters; D J Mela; P J Rogers
Journal:  Eur J Clin Nutr       Date:  2010-09-22       Impact factor: 4.016

4.  Long-term effects of consumption of a novel fat emulsion in relation to body-weight management.

Authors:  K Diepvens; S Soenen; J Steijns; M Arnold; M Westerterp-Plantenga
Journal:  Int J Obes (Lond)       Date:  2007-02-13       Impact factor: 5.095

5.  Effect of ileal fat perfusion on satiety and hormone release in healthy volunteers.

Authors:  P W J Maljaars; T Symersky; B C Kee; E Haddeman; H P F Peters; A A M Masclee
Journal:  Int J Obes (Lond)       Date:  2008-09-16       Impact factor: 5.095

6.  The emulsified lipid Fabuless (Olibra) does not decrease food intake but suppresses appetite when consumed with yoghurt but not alone or with solid foods: a food effect study.

Authors:  Y-K Chan; C M Strik; S C Budgett; A-T McGill; J Proctor; S D Poppitt
Journal:  Physiol Behav       Date:  2011-09-17

7.  Circulating ghrelin and GLP-1 are not affected by habitual diet.

Authors:  Amy C Ellis; Paula Chandler-Laney; Krista Casazza; Laura Lee Goree; Gerald McGwin; Barbara A Gower
Journal:  Regul Pept       Date:  2012-02-28

8.  Slowly and rapidly digested fat emulsions are equally satiating but their triglycerides are differentially absorbed and metabolized in humans.

Authors:  Jennifer B Keogh; Tim J Wooster; Matthew Golding; Li Day; Bärbel Otto; Peter M Clifton
Journal:  J Nutr       Date:  2011-03-16       Impact factor: 4.798

9.  Investigation of the medium-term effects of Olibratrade mark fat emulsion on food intake in non-obese subjects.

Authors:  C M Logan; T A McCaffrey; J M W Wallace; P J Robson; R W Welch; A Dunne; M B E Livingstone
Journal:  Eur J Clin Nutr       Date:  2006-03-15       Impact factor: 4.016

10.  Effect of a low dose of intraduodenal fat on satiety in humans: studies using the type A cholecystokinin receptor antagonist loxiglumide.

Authors:  R J Lieverse; J B Jansen; A A Masclee; L C Rovati; C B Lamers
Journal:  Gut       Date:  1994-04       Impact factor: 23.059

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