D Mitra1, A K Shaw, K Hutchings. 1. Centre for Chronic Disease Prevention and Control, Public Health Agency of Canada, Ottawa, Ontario, Canada. debjani.mitra@phac-aspc.gc.ca
Abstract
INTRODUCTION: Cancer is the leading cause of disease-related death in children aged 1 to 14 years in Canada. Despite the importance to public health of childhood cancer, there have been few reports on Canadian trends published in the peer-reviewed literature. This study examines childhood cancer trends by age, sex, and province of residence using the most current cancer registration data. METHODS: Data from the population-based Canadian Cancer Registry were used to compute incidence trends in primary cancers diagnosed between 1992 and 2006 in children (0-14 years) for the 12 major diagnostic groups of the International Classification of Childhood Cancer, 3rd Edition. RESULTS: Between 1992 and 2006, incidence rates for all cancers remained stable, although trends varied by cancer type. We observed a significant decrease in retinoblastoma in boys for the entire period (-6.5% per year) and an increase in leukemia from 1992 to 1999 (+3.5% per year). In girls, there was a significant decrease in renal tumours from 1998 to 2006 (-5.7% per year) and an increase in hepatic tumours from 1997 to 2006 (+8.1% per year). Differences by age and province were also apparent. Some caution should be exercised when interpreting trends involving a small number of cases per year and those with wide 95% confidence intervals. CONCLUSIONS: Our findings suggest an ongoing need for population-based surveillance and etiologic research.
INTRODUCTION:Cancer is the leading cause of disease-related death in children aged 1 to 14 years in Canada. Despite the importance to public health of childhood cancer, there have been few reports on Canadian trends published in the peer-reviewed literature. This study examines childhood cancer trends by age, sex, and province of residence using the most current cancer registration data. METHODS: Data from the population-based Canadian Cancer Registry were used to compute incidence trends in primary cancers diagnosed between 1992 and 2006 in children (0-14 years) for the 12 major diagnostic groups of the International Classification of Childhood Cancer, 3rd Edition. RESULTS: Between 1992 and 2006, incidence rates for all cancers remained stable, although trends varied by cancer type. We observed a significant decrease in retinoblastoma in boys for the entire period (-6.5% per year) and an increase in leukemia from 1992 to 1999 (+3.5% per year). In girls, there was a significant decrease in renal tumours from 1998 to 2006 (-5.7% per year) and an increase in hepatic tumours from 1997 to 2006 (+8.1% per year). Differences by age and province were also apparent. Some caution should be exercised when interpreting trends involving a small number of cases per year and those with wide 95% confidence intervals. CONCLUSIONS: Our findings suggest an ongoing need for population-based surveillance and etiologic research.
Authors: Pablo Zoroquiain; Patrick Logan; Vasco Bravo-Filho; Natalia Vila; Samir Jabbour; Maria Eugenia Orellana; Miguel N Burnier Journal: Ocul Oncol Pathol Date: 2015-05-06
Authors: D Mitra; K Hutchings; A Shaw; R Barber; L Sung; M Bernstein; A S Carret; V Barbaros; M McBride; L Parker; M Stewart; C Strahlendorf Journal: Health Promot Chronic Dis Prev Can Date: 2015-06 Impact factor: 3.240
Authors: Hyeon Jin Park; Eun-Kyeong Moon; Ju Young Yoon; Chang-Mo Oh; Kyu-Won Jung; Byung Kiu Park; Hee Young Shin; Young-Joo Won Journal: Cancer Res Treat Date: 2016-01-21 Impact factor: 4.679