Literature DB >> 22754269

The effects of error magnitude and bandwidth selection for deconvolution with unknown error distribution.

Xiao-Feng Wang1, Deping Ye.   

Abstract

The error distribution is generally unknown in deconvolution problems with real applications. A separate independent experiment is thus often conducted to collect the additional noise data in those studies. In this paper, we study the nonparametric deconvolution estimation from a contaminated sample coupled with an additional noise sample. A ridge-based kernel deconvolution estimator is proposed and its asymptotic properties are investigated depending on the error magnitude. We then present a data-driven bandwidth selection algorithm with combining the bootstrap method and the idea of simulation extrapolation. The finite sample performance of the proposed methods and the effects of error magnitude are evaluated through simulation studies. A real data analysis for a gene Illumina BeadArray study is performed to illustrate the use of the proposed methods.

Entities:  

Year:  2012        PMID: 22754269      PMCID: PMC3383633          DOI: 10.1080/10485252.2011.647024

Source DB:  PubMed          Journal:  J Nonparametr Stat        ISSN: 1026-7654            Impact factor:   1.231


  8 in total

1.  Exploration, normalization, and summaries of high density oligonucleotide array probe level data.

Authors:  Rafael A Irizarry; Bridget Hobbs; Francois Collin; Yasmin D Beazer-Barclay; Kristen J Antonellis; Uwe Scherf; Terence P Speed
Journal:  Biostatistics       Date:  2003-04       Impact factor: 5.899

2.  Statistical methods of background correction for Illumina BeadArray data.

Authors:  Yang Xie; Xinlei Wang; Michael Story
Journal:  Bioinformatics       Date:  2009-02-04       Impact factor: 6.937

3.  Normalizing bead-based microRNA expression data: a measurement error model-based approach.

Authors:  Bin Wang; Xiao-Feng Wang; Yaguang Xi
Journal:  Bioinformatics       Date:  2011-04-15       Impact factor: 6.937

4.  Deconvolution Estimation in Measurement Error Models: The R Package decon.

Authors:  Xiao-Feng Wang; Bin Wang
Journal:  J Stat Softw       Date:  2011-03-01       Impact factor: 6.440

5.  On nonparametric comparison of images and regression surfaces.

Authors:  Xiao-Feng Wang; Deping Ye
Journal:  J Stat Plan Inference       Date:  2010-10-01       Impact factor: 1.111

6.  Estimating smooth distribution function in the presence of heteroscedastic measurement errors.

Authors:  Xiao-Feng Wang; Zhaozhi Fan; Bin Wang
Journal:  Comput Stat Data Anal       Date:  2010-01-01       Impact factor: 1.681

7.  Microarray background correction: maximum likelihood estimation for the normal-exponential convolution.

Authors:  Jeremy D Silver; Matthew E Ritchie; Gordon K Smyth
Journal:  Biostatistics       Date:  2008-12-08       Impact factor: 5.899

8.  Statistical issues in the analysis of Illumina data.

Authors:  Mark J Dunning; Nuno L Barbosa-Morais; Andy G Lynch; Simon Tavaré; Matthew E Ritchie
Journal:  BMC Bioinformatics       Date:  2008-02-06       Impact factor: 3.169

  8 in total
  3 in total

1.  Conditional Density Estimation in Measurement Error Problems.

Authors:  Xiao-Feng Wang; Deping Ye
Journal:  J Multivar Anal       Date:  2015-01-01       Impact factor: 1.473

2.  Generalization of the normal-exponential model: exploration of a more accurate parametrisation for the signal distribution on Illumina BeadArrays.

Authors:  Sandra Plancade; Yves Rozenholc; Eiliv Lund
Journal:  BMC Bioinformatics       Date:  2012-12-11       Impact factor: 3.169

3.  Testing for differentially-expressed microRNAs with errors-in-variables nonparametric regression.

Authors:  Bin Wang; Shu-Guang Zhang; Xiao-Feng Wang; Ming Tan; Yaguang Xi
Journal:  PLoS One       Date:  2012-05-24       Impact factor: 3.240

  3 in total

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