Literature DB >> 22752704

Biological indeterminacy.

Ralph J Greenspan1.   

Abstract

Reductionist explanations in biology generally assume that biological mechanisms are highly deterministic and basically similar between individuals. A contrasting view has emerged recently that takes into account the degeneracy of biological processes--the ability to arrive at a given endpoint by a variety of available paths, even within the same individual. This perspective casts significant doubt on the prospects for the ability to predict behavior accurately based on brain imaging or genotyping, and on the ability of neuroscience to stipulate ethics.

Mesh:

Year:  2012        PMID: 22752704     DOI: 10.1007/s11948-012-9379-2

Source DB:  PubMed          Journal:  Sci Eng Ethics        ISSN: 1353-3452            Impact factor:   3.525


  10 in total

1.  Increased synchronization of neuromagnetic responses during conscious perception.

Authors:  R Srinivasan; D P Russell; G M Edelman; G Tononi
Journal:  J Neurosci       Date:  1999-07-01       Impact factor: 6.167

Review 2.  Principles for the buffering of genetic variation.

Authors:  J L Hartman; B Garvik; L Hartwell
Journal:  Science       Date:  2001-02-09       Impact factor: 47.728

Review 3.  The flexible genome.

Authors:  R J Greenspan
Journal:  Nat Rev Genet       Date:  2001-05       Impact factor: 53.242

4.  Identification of genes involved in Drosophila melanogaster geotaxis, a complex behavioral trait.

Authors:  Daniel P Toma; Kevin P White; Jerry Hirsch; Ralph J Greenspan
Journal:  Nat Genet       Date:  2002-06-03       Impact factor: 38.330

5.  BEHAVIOR GENETICS AND INDIVIDUALITY UNDERSTOOD.

Authors:  J HIRSCH
Journal:  Science       Date:  1963-12-13       Impact factor: 47.728

Review 6.  Selection, gene interaction, and flexible gene networks.

Authors:  R J Greenspan
Journal:  Cold Spring Harb Symp Quant Biol       Date:  2009-11-10

7.  Complexity and coherency: integrating information in the brain.

Authors:  G Tononi; G M Edelman; O Sporns
Journal:  Trends Cogn Sci       Date:  1998-12-01       Impact factor: 20.229

8.  Evolution of genetic redundancy.

Authors:  M A Nowak; M C Boerlijst; J Cooke; J M Smith
Journal:  Nature       Date:  1997-07-10       Impact factor: 49.962

9.  The spandrels of San Marco and the Panglossian paradigm: a critique of the adaptationist programme.

Authors:  S J Gould; R C Lewontin
Journal:  Proc R Soc Lond B Biol Sci       Date:  1979-09-21

10.  Consistency in nervous systems: trial-to-trial and animal-to-animal variations in the responses to repeated applications of a sensory stimulus in Aplysia.

Authors:  J Y Wu; Y Tsau; H P Hopp; L B Cohen; A C Tang; C X Falk
Journal:  J Neurosci       Date:  1994-03       Impact factor: 6.167

  10 in total
  6 in total

1.  Editors' overview: Neuroethics: many voices and many stories.

Authors:  Michael Kalichman; Dena Plemmons; Stephanie J Bird
Journal:  Sci Eng Ethics       Date:  2012-09-29       Impact factor: 3.525

Review 2.  On the Self-Organizing Origins of Agency.

Authors:  J A Scott Kelso
Journal:  Trends Cogn Sci       Date:  2016-05-18       Impact factor: 20.229

3.  Genomic responses to the socio-sexual environment in male Drosophila melanogaster exposed to conspecific rivals.

Authors:  Irina Mohorianu; Amanda Bretman; Damian T Smith; Emily K Fowler; Tamas Dalmay; Tracey Chapman
Journal:  RNA       Date:  2017-04-20       Impact factor: 4.942

4.  Fitness consequences of redundant cues of competition in male Drosophila melanogaster.

Authors:  Alice A Dore; Amanda Bretman; Tracey Chapman
Journal:  Ecol Evol       Date:  2020-05-04       Impact factor: 2.912

5.  Degeneracy and Complexity in Neuro-Behavioral Correlates of Team Coordination.

Authors:  Silke Dodel; Emmanuelle Tognoli; J A Scott Kelso
Journal:  Front Hum Neurosci       Date:  2020-09-10       Impact factor: 3.169

6.  "Feature Detection" vs. "Predictive Coding" Models of Plant Behavior.

Authors:  Paco Calvo; František Baluška; Andrew Sims
Journal:  Front Psychol       Date:  2016-10-04
  6 in total

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