Literature DB >> 22752068

Safety of weightlifting among women with or at risk for breast cancer-related lymphedema: musculoskeletal injuries and health care use in a weightlifting rehabilitation trial.

Justin C Brown1, Andrea B Troxel, Kathryn H Schmitz.   

Abstract

INTRODUCTION: It has been noted that only 14% of all clinical trials are translated into practice. The objective of this paper is to promote translation of an efficacious rehabilitative exercise program for breast cancer survivors by clarifying for clinicians the safety profile of participants (e.g., rates of musculoskeletal injury and referral to medical professionals), and to use this evidence to make recommendations on the appropriate training of health and fitness staff who would be capable of safely, effectively, and sustainably delivering the program.
METHODS: Breast cancer survivors with and at risk for lymphedema were randomized to twice-weekly weightlifting or standard care for 1 year. An injury survey and health care evaluation were administered after 1 year and in 3-month intervals, respectively.
RESULTS: The cumulative incidence and rate of injury were higher in the weightlifting than in the control group. The injury rates were 2.3 and 0.3 per 1,000 bouts of weightlifting among breast cancer survivors with and at risk for lymphedema, respectively. Among breast cancer survivors with or at risk for lymphedema, 20.9% in the weightlifting group had an encounter with a health care provider that required cessation or dose modification of weightlifting.
CONCLUSION: Despite the demonstrated efficacy of weightlifting, musculoskeletal injuries and other health problems did occur. Therefore, for the successful translation of this rehabilitative intervention into clinical practice, health and fitness professionals working with breast cancer survivors need the knowledge, skills, and abilities that clarify their scope of practice to address these health care needs.

Entities:  

Mesh:

Year:  2012        PMID: 22752068      PMCID: PMC3425531          DOI: 10.1634/theoncologist.2012-0035

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  19 in total

1.  Development and validation of a telephone questionnaire to characterize lymphedema in women treated for breast cancer.

Authors:  S A Norman; L T Miller; H B Erikson; M F Norman; R McCorkle
Journal:  Phys Ther       Date:  2001-06

2.  The International Physical Activity Questionnaire (IPAQ): a study of concurrent and construct validity.

Authors:  Maria Hagströmer; Pekka Oja; Michael Sjöström
Journal:  Public Health Nutr       Date:  2006-09       Impact factor: 4.022

3.  A comparison of four diagnostic criteria for lymphedema in a post-breast cancer population.

Authors:  Jane M Armer; Bob R Stewart
Journal:  Lymphat Res Biol       Date:  2005       Impact factor: 2.589

Review 4.  Exercise for secondary prevention of breast cancer: moving from evidence to changing clinical practice.

Authors:  Kathryn H Schmitz
Journal:  Cancer Prev Res (Phila)       Date:  2011-04

Review 5.  Evidence-based risk assessment and recommendations for physical activity clearance: cancer.

Authors:  Lee W Jones
Journal:  Appl Physiol Nutr Metab       Date:  2011-07       Impact factor: 2.665

6.  Safety and efficacy of weight training in recent breast cancer survivors to alter body composition, insulin, and insulin-like growth factor axis proteins.

Authors:  Kathryn H Schmitz; Rehana L Ahmed; Peter J Hannan; Douglas Yee
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2005-07       Impact factor: 4.254

7.  Strength training and adiposity in premenopausal women: strong, healthy, and empowered study.

Authors:  Kathryn H Schmitz; Peter J Hannan; Steven D Stovitz; Cathy J Bryan; Meghan Warren; Michael D Jensen
Journal:  Am J Clin Nutr       Date:  2007-09       Impact factor: 7.045

8.  Safety of strength training in premenopausal women: musculoskeletal injuries from a two-year randomized trial.

Authors:  Meghan Warren; Kathryn H Schmitz
Journal:  Am J Health Promot       Date:  2009 May-Jun

Review 9.  The pathophysiology of lymphedema.

Authors:  P S Mortimer
Journal:  Cancer       Date:  1998-12-15       Impact factor: 6.860

10.  Factors associated with increased breast cancer-related lymphedema volume.

Authors:  Stephane Vignes; Maria Arrault; Alain Dupuy
Journal:  Acta Oncol       Date:  2007       Impact factor: 4.089

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  19 in total

1.  Prescription and adherence to lymphedema self-care modalities among women with breast cancer-related lymphedema.

Authors:  Justin C Brown; Andrea L Cheville; Julia C Tchou; Susan R Harris; Kathryn H Schmitz
Journal:  Support Care Cancer       Date:  2013-09-07       Impact factor: 3.603

2.  Weight lifting and appendicular skeletal muscle mass among breast cancer survivors: a randomized controlled trial.

Authors:  Justin C Brown; Kathryn H Schmitz
Journal:  Breast Cancer Res Treat       Date:  2015-05-03       Impact factor: 4.872

3.  Weight Lifting and Physical Function Among Survivors of Breast Cancer: A Post Hoc Analysis of a Randomized Controlled Trial.

Authors:  Justin C Brown; Kathryn H Schmitz
Journal:  J Clin Oncol       Date:  2015-05-11       Impact factor: 44.544

4.  Survivorship, Version 2.2018, NCCN Clinical Practice Guidelines in Oncology.

Authors:  Crystal S Denlinger; Tara Sanft; K Scott Baker; Gregory Broderick; Wendy Demark-Wahnefried; Debra L Friedman; Mindy Goldman; Melissa Hudson; Nazanin Khakpour; Allison King; Divya Koura; Robin M Lally; Terry S Langbaum; Allison L McDonough; Michelle Melisko; Jose G Montoya; Kathi Mooney; Javid J Moslehi; Tracey O'Connor; Linda Overholser; Electra D Paskett; Jeffrey Peppercorn; William Pirl; M Alma Rodriguez; Kathryn J Ruddy; Paula Silverman; Sophia Smith; Karen L Syrjala; Amye Tevaarwerk; Susan G Urba; Mark T Wakabayashi; Phyllis Zee; Nicole R McMillian; Deborah A Freedman-Cass
Journal:  J Natl Compr Canc Netw       Date:  2018-10       Impact factor: 11.908

5.  The dose-response effects of aerobic exercise on musculoskeletal injury: a post hoc analysis of a randomized trial.

Authors:  Justin C Brown; Kathryn H Schmitz
Journal:  Res Sports Med       Date:  2017-04-06       Impact factor: 4.674

6.  A randomized phase II dose-response exercise trial among colon cancer survivors: Purpose, study design, methods, and recruitment results.

Authors:  Justin C Brown; Andrea B Troxel; Bonnie Ky; Nevena Damjanov; Babette S Zemel; Michael R Rickels; Andrew D Rhim; Anil K Rustgi; Kerry S Courneya; Kathryn H Schmitz
Journal:  Contemp Clin Trials       Date:  2016-03-10       Impact factor: 2.226

7.  Development of a risk-screening tool for cancer survivors to participate in unsupervised moderate- to vigorous-intensity exercise: results from a survey study.

Authors:  Justin C Brown; Emily M Ko; Kathryn H Schmitz
Journal:  PM R       Date:  2014-09-10       Impact factor: 2.298

Review 8.  The Independent Effects of Strength Training in Cancer Survivors: a Systematic Review.

Authors:  Erik D Hanson; Chad W Wagoner; Travis Anderson; Claudio L Battaglini
Journal:  Curr Oncol Rep       Date:  2016-05       Impact factor: 5.075

9.  Survivorship: healthy lifestyles, version 2.2014.

Authors:  Crystal S Denlinger; Jennifer A Ligibel; Madhuri Are; K Scott Baker; Wendy Demark-Wahnefried; Don Dizon; Debra L Friedman; Mindy Goldman; Lee Jones; Allison King; Grace H Ku; Elizabeth Kvale; Terry S Langbaum; Kristin Leonardi-Warren; Mary S McCabe; Michelle Melisko; Jose G Montoya; Kathi Mooney; Mary Ann Morgan; Javid J Moslehi; Tracey O'Connor; Linda Overholser; Electra D Paskett; Jeffrey Peppercorn; Muhammad Raza; M Alma Rodriguez; Karen L Syrjala; Susan G Urba; Mark T Wakabayashi; Phyllis Zee; Nicole R McMillian; Deborah A Freedman-Cass
Journal:  J Natl Compr Canc Netw       Date:  2014-09       Impact factor: 11.908

Review 10.  Weight management and physical activity throughout the cancer care continuum.

Authors:  Wendy Demark-Wahnefried; Kathryn H Schmitz; Catherine M Alfano; Jennifer R Bail; Pamela J Goodwin; Cynthia A Thomson; Don W Bradley; Kerry S Courneya; Christie A Befort; Crystal S Denlinger; Jennifer A Ligibel; William H Dietz; Melinda R Stolley; Melinda L Irwin; Marcas M Bamman; Caroline M Apovian; Bernardine M Pinto; Kathleen Y Wolin; Rachel M Ballard; Andrew J Dannenberg; Elizabeth G Eakin; Matt M Longjohn; Susan D Raffa; Lucile L Adams-Campbell; Joanne S Buzaglo; Sharyl J Nass; Greta M Massetti; Erin P Balogh; Elizabeth S Kraft; Anand K Parekh; Darshak M Sanghavi; G Stephen Morris; Karen Basen-Engquist
Journal:  CA Cancer J Clin       Date:  2017-11-22       Impact factor: 508.702

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