Literature DB >> 22750270

Regulation of GPCR-mediated smooth muscle contraction: implications for asthma and pulmonary hypertension.

D B Wright1, S Tripathi, A Sikarwar, K T Santosh, J Perez-Zoghbi, O O Ojo, N Irechukwu, J P T Ward, D Schaafsma.   

Abstract

Contractile G-protein-coupled receptors (GPCRs) have emerged as key regulators of smooth muscle contraction, both under healthy and diseased conditions. This brief review will discuss some key topics and novel insights regarding GPCR-mediated airway and vascular smooth muscle contraction as discussed at the 7th International Young Investigators' Symposium on Smooth Muscle (2011, Winnipeg, Manitoba, Canada) and will in particular focus on processes driving Ca(2+)-mobilization and -sensitization.
Copyright © 2012 Elsevier Ltd. All rights reserved.

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Year:  2012        PMID: 22750270     DOI: 10.1016/j.pupt.2012.06.005

Source DB:  PubMed          Journal:  Pulm Pharmacol Ther        ISSN: 1094-5539            Impact factor:   3.410


  20 in total

Review 1.  Emerging concepts in smooth muscle contributions to airway structure and function: implications for health and disease.

Authors:  Y S Prakash
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-10-14       Impact factor: 5.464

2.  Bitter tasting compounds dilate airways by inhibiting airway smooth muscle calcium oscillations and calcium sensitivity.

Authors:  Xiahui Tan; Michael J Sanderson
Journal:  Br J Pharmacol       Date:  2014-02       Impact factor: 8.739

3.  Pathogenic role of calcium-sensing receptors in the development and progression of pulmonary hypertension.

Authors:  Haiyang Tang; Aya Yamamura; Hisao Yamamura; Shanshan Song; Dustin R Fraidenburg; Jiwang Chen; Yali Gu; Nicole M Pohl; Tong Zhou; Laura Jiménez-Pérez; Ramon J Ayon; Ankit A Desai; David Goltzman; Franz Rischard; Zain Khalpey; Stephan M Black; Joe G N Garcia; Ayako Makino; Jason X J Yuan
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-03-11       Impact factor: 5.464

Review 4.  Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM).

Authors:  Philippe Delmotte; Gary C Sieck
Journal:  Can J Physiol Pharmacol       Date:  2014-11-25       Impact factor: 2.273

5.  Active components of ginger potentiate β-agonist-induced relaxation of airway smooth muscle by modulating cytoskeletal regulatory proteins.

Authors:  Elizabeth A Townsend; Yi Zhang; Carrie Xu; Ryo Wakita; Charles W Emala
Journal:  Am J Respir Cell Mol Biol       Date:  2014-01       Impact factor: 6.914

Review 6.  Airway smooth muscle in airway reactivity and remodeling: what have we learned?

Authors:  Y S Prakash
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2013-10-18       Impact factor: 5.464

Review 7.  Class C GPCRs in the airway.

Authors:  Brijeshkumar S Patel; Jovanka Ravix; Christina Pabelick; Y S Prakash
Journal:  Curr Opin Pharmacol       Date:  2020-05-04       Impact factor: 5.547

8.  Mechanisms of BDNF regulation in asthmatic airway smooth muscle.

Authors:  Bharathi Aravamudan; Michael A Thompson; Christina M Pabelick; Y S Prakash
Journal:  Am J Physiol Lung Cell Mol Physiol       Date:  2016-06-17       Impact factor: 5.464

9.  Bitter Taste Receptors in the Airway Cells Functions.

Authors:  Pawan Sharma; Stanley Conaway; Deepak Deshpande
Journal:  Handb Exp Pharmacol       Date:  2022

10.  A Ca2+- and PKC-driven regulatory network in airway smooth muscle.

Authors:  Rose E Dixon; Luis F Santana
Journal:  J Gen Physiol       Date:  2013-02       Impact factor: 4.086

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