OBJECTIVE: To examine the association of vegetable and fruit consumption with the risk of non-gallstone-related acute pancreatitis. DESIGN: A population-based prospective cohort of 80,019 women and men, aged 46-84 years, completed a food-frequency questionnaire at baseline and was followed up for incidence of non-gallstone-related acute pancreatitis from 1 January 1998 to 31 December 2009. Participants were categorised into quintiles according to consumption of vegetables and consumption of fruit. Cox proportional hazards models were used to estimate RRs and 95% CIs. RESULTS: In total, 320 incident cases (216 men and 104 women) with non-gallstone-related acute pancreatitis were identified during 12 years of follow-up (891,136 person-years). After adjustment for potential confounders, the authors observed a significant inverse linear dose-response association between vegetable consumption and risk of non-gallstone-related acute pancreatitis; every two additional servings per day were associated with 17% risk reduction (RR=0.83; 95% CI 0.70 to 0.98; p=0.03). Among participants consuming >1 drink of alcohol per day and among those with body mass index ≥25 kg/m2, the RR for the highest compared with the lowest quintile of vegetable consumption was 0.29 (95% CI 0.13 to 0.67) and 0.49 (95% CI 0.29 to 0.85), respectively. Fruit consumption was not significantly associated with the risk of non-gallstone-related acute pancreatitis; the RR comparing extreme quintiles of consumption was 1.20 (95% CI 0.81 to 1.78). CONCLUSIONS: Vegetable consumption, but not fruit consumption, may play a role in the prevention of non-gallstone-related acute pancreatitis.
OBJECTIVE: To examine the association of vegetable and fruit consumption with the risk of non-gallstone-related acute pancreatitis. DESIGN: A population-based prospective cohort of 80,019 women and men, aged 46-84 years, completed a food-frequency questionnaire at baseline and was followed up for incidence of non-gallstone-related acute pancreatitis from 1 January 1998 to 31 December 2009. Participants were categorised into quintiles according to consumption of vegetables and consumption of fruit. Cox proportional hazards models were used to estimate RRs and 95% CIs. RESULTS: In total, 320 incident cases (216 men and 104 women) with non-gallstone-related acute pancreatitis were identified during 12 years of follow-up (891,136 person-years). After adjustment for potential confounders, the authors observed a significant inverse linear dose-response association between vegetable consumption and risk of non-gallstone-related acute pancreatitis; every two additional servings per day were associated with 17% risk reduction (RR=0.83; 95% CI 0.70 to 0.98; p=0.03). Among participants consuming >1 drink of alcohol per day and among those with body mass index ≥25 kg/m2, the RR for the highest compared with the lowest quintile of vegetable consumption was 0.29 (95% CI 0.13 to 0.67) and 0.49 (95% CI 0.29 to 0.85), respectively. Fruit consumption was not significantly associated with the risk of non-gallstone-related acute pancreatitis; the RR comparing extreme quintiles of consumption was 1.20 (95% CI 0.81 to 1.78). CONCLUSIONS: Vegetable consumption, but not fruit consumption, may play a role in the prevention of non-gallstone-related acute pancreatitis.
Authors: Dagfinn Aune; Edward Giovannucci; Paolo Boffetta; Lars T Fadnes; NaNa Keum; Teresa Norat; Darren C Greenwood; Elio Riboli; Lars J Vatten; Serena Tonstad Journal: Int J Epidemiol Date: 2017-06-01 Impact factor: 7.196
Authors: Mohannad Dugum; Amir Gougol; Pedram Paragomi; Xiaotian Gao; Bassem Matta; Cemal Yazici; Gong Tang; Phil Greer; Ioannis Pothoulakis; Stephen J D O'Keefe; David C Whitcomb; Dhiraj Yadav; Georgios I Papachristou Journal: Curr Dev Nutr Date: 2018-10-08
Authors: Balázs Koncz; Erika Darvasi; Dalma Erdősi; Andrea Szentesi; Katalin Márta; Bálint Erőss; Dániel Pécsi; Zoltán Gyöngyi; János Girán; Nelli Farkas; Maria Papp; Eszter Fehér; Zsuzsanna Vitális; Tamás Janka; Áron Vincze; Ferenc Izbéki; Veronika Dunás-Varga; László Gajdán; Imola Török; Sándor Károly; Judit Antal; Noémi Zádori; Markus M Lerch; John Neoptolemos; Miklós Sahin-Tóth; Ole H Petersen; Péter Hegyi Journal: BMJ Open Date: 2020-01-06 Impact factor: 2.692
Authors: Ying Zhou; Ningbo Hao; Zhongping Duan; Ming Kong; Manman Xu; Dan Zhang; Xiangxiang Xu; Qingwen Yuan; Changzheng Li Journal: Int J Gen Med Date: 2021-07-27