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Literature DB >> 22740399

Human papillomaviruses recruit cellular DNA repair and homologous recombination factors to viral replication centers.

Kenric A Gillespie¹, Kavi P Mehta, Laimonis A Laimins, Cary A Moody.

Abstract

Human papillomaviruses (HPV) activate the ataxia telangiectasia mutated (ATM)-dependent DNA damage response to induce viral genome amplification upon epithelial differentiation. Our studies show that along with members of the ATM pathway, HPV proteins also localize factors involved in homologous DNA recombination to distinct nuclear foci that contain HPV genomes and cellular replication factors. These studies indicate that HPV activates the ATM pathway to recruit repair factors to viral genomes and allow for efficient replication.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22740399 PMCID： PMC3416172 DOI： 10.1128/JVI.00247-12

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

45 in total

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Authors: Ji-Hoon Lee; Tanya T Paull
Journal: Science Date: 2005-03-24 Impact factor: 47.728

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Journal: J Virol Date: 1997-10 Impact factor: 5.103

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Journal: Oncogene Date: 2006-02-02 Impact factor: 9.867

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Authors: Jonathan E Nuss; Steve M Patrick; Greg G Oakley; Gerald M Alter; Jacob G Robison; Kathleen Dixon; John J Turchi
Journal: Biochemistry Date: 2005-06-14 Impact factor: 3.162

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Authors: Jacob Falck; Julia Coates; Stephen P Jackson
Journal: Nature Date: 2005-03-02 Impact factor: 49.962

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Authors: W Stünkel; H U Bernard
Journal: J Virol Date: 1999-03 Impact factor: 5.103

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Authors: C S Swindle; N Zou; B A Van Tine; G M Shaw; J A Engler; L T Chow
Journal: J Virol Date: 1999-02 Impact factor: 5.103

Review 9. Functions of human replication protein A (RPA): from DNA replication to DNA damage and stress responses.

Authors: Yue Zou; Yiyong Liu; Xiaoming Wu; Steven M Shell
Journal: J Cell Physiol Date: 2006-08 Impact factor: 6.384

10. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Authors: Shuhei Matsuoka; Bryan A Ballif; Agata Smogorzewska; E Robert McDonald; Kristen E Hurov; Ji Luo; Corey E Bakalarski; Zhenming Zhao; Nicole Solimini; Yaniv Lerenthal; Yosef Shiloh; Steven P Gygi; Stephen J Elledge
Journal: Science Date: 2007-05-25 Impact factor: 47.728

113 in total

Review 1. The E1 proteins.

Authors: Monika Bergvall; Thomas Melendy; Jacques Archambault
Journal: Virology Date: 2013-09-10 Impact factor: 3.616

2. Productive replication of human papillomavirus 31 requires DNA repair factor Nbs1.

Authors: Daniel C Anacker; Dipendra Gautam; Kenric A Gillespie; William H Chappell; Cary A Moody
Journal: J Virol Date: 2014-05-21 Impact factor: 5.103

3. CD66+ cells in cervical precancers are partially differentiated progenitors with neoplastic traits.

Authors: Chitra Pattabiraman; Shiyuan Hong; Vignesh K Gunasekharan; Annapurna Pranatharthi; Jeevisha Bajaj; Sweta Srivastava; H Krishnamurthy; Aswathy Ammothumkandy; Venkat G Giri; Laimonis A Laimins; Sudhir Krishna
Journal: Cancer Res Date: 2014-09-29 Impact factor: 12.701

4. The SMC5/6 Complex Interacts with the Papillomavirus E2 Protein and Influences Maintenance of Viral Episomal DNA.

Authors: Peris Bentley; Min Jie Alvin Tan; Alison A McBride; Elizabeth A White; Peter M Howley
Journal: J Virol Date: 2018-07-17 Impact factor: 5.103

5. Mediation by peer violence victimization of sexual orientation disparities in cancer-related tobacco, alcohol, and sexual risk behaviors: pooled youth risk behavior surveys.

Authors: Margaret Rosario; Heather L Corliss; Bethany G Everett; Stephen T Russell; Francisco O Buchting; Michelle A Birkett
Journal: Am J Public Health Date: 2014-04-17 Impact factor: 9.308