Literature DB >> 22737693

Attainment and stability of sustained symptomatic remission and recovery among patients with borderline personality disorder and axis II comparison subjects: a 16-year prospective follow-up study.

Mary C Zanarini1, Frances R Frankenburg, D Bradford Reich, Garrett Fitzmaurice.   

Abstract

OBJECTIVE: The purposes of this study were to determine time to attainment of symptom remission and to recovery lasting 2, 4, 6, or 8 years among patients with borderline personality disorder and comparison subjects with other personality disorders and to determine the stability of these outcomes.
METHOD: A total of 290 inpatients with borderline personality disorder and 72 comparison subjects with other axis II disorders were assessed during their index admission using a series of semistructured interviews, which were administered again at eight successive 2-year follow-up sessions. For inclusion in the study, patients with borderline personality disorder had to meet criteria for both the Revised Diagnostic Interview for Borderlines and DSM-III-R.
RESULTS: Borderline patients were significantly slower to achieve remission or recovery (which involved good social and vocational functioning as well as symptomatic remission) than axis II comparison subjects. However, by the time of the 16-year follow-up assessment, both groups had achieved similarly high rates of remission (range for borderline patients: 78%-99%; range for axis II comparison subjects: 97%-99%) but not recovery (40%-60% compared with 75%-85%). In contrast, symptomatic recurrence and loss of recovery occurred more rapidly and at substantially higher rates among borderline patients than axis II comparison subjects (recurrence: 10%-36% compared with 4%-7%; loss of recovery: 20%-44% compared with 9%-28%).
CONCLUSIONS: Our results suggest that sustained symptomatic remission is substantially more common than sustained recovery from borderline personality disorder and that sustained remissions and recoveries are substantially more difficult for individuals with borderline personality disorder to attain and maintain than for individuals with other forms of personality disorder.

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Mesh:

Year:  2012        PMID: 22737693      PMCID: PMC3509999          DOI: 10.1176/appi.ajp.2011.11101550

Source DB:  PubMed          Journal:  Am J Psychiatry        ISSN: 0002-953X            Impact factor:   18.112


  23 in total

1.  Inter-rater and test-retest reliability of the Revised Diagnostic Interview for Borderlines.

Authors:  Mary C Zanarini; Frances R Frankenburg; A Anna Vujanovic
Journal:  J Pers Disord       Date:  2002-06

2.  The Structured Clinical Interview for DSM-III-R (SCID). I: History, rationale, and description.

Authors:  R L Spitzer; J B Williams; M Gibbon; M B First
Journal:  Arch Gen Psychiatry       Date:  1992-08

3.  The diagnostic Interview for Personality Disorders: interrater and test-retest reliability.

Authors:  M C Zanarini; F R Frankenburg; D L Chauncey; J G Gunderson
Journal:  Compr Psychiatry       Date:  1987 Nov-Dec       Impact factor: 3.735

4.  Long-term follow-up of borderline patients in a general hospital.

Authors:  J Paris; R Brown; D Nowlis
Journal:  Compr Psychiatry       Date:  1987 Nov-Dec       Impact factor: 3.735

5.  Attainment and maintenance of reliability of axis I and II disorders over the course of a longitudinal study.

Authors:  M C Zanarini; F R Frankenburg
Journal:  Compr Psychiatry       Date:  2001 Sep-Oct       Impact factor: 3.735

6.  14-year follow-up of borderline and schizotypal personality disorders.

Authors:  E M Plakun; P E Burkhardt; J P Muller
Journal:  Compr Psychiatry       Date:  1985 Sep-Oct       Impact factor: 3.735

7.  The long-term natural history of the weekly symptomatic status of bipolar I disorder.

Authors:  Lewis L Judd; Hagop S Akiskal; Pamela J Schettler; Jean Endicott; Jack Maser; David A Solomon; Andrew C Leon; John A Rice; Martin B Keller
Journal:  Arch Gen Psychiatry       Date:  2002-06

8.  The Collaborative Longitudinal Personality Disorders Study: baseline Axis I/II and II/II diagnostic co-occurrence.

Authors:  T H McGlashan; C M Grilo; A E Skodol; J G Gunderson; M T Shea; L C Morey; M C Zanarini; R L Stout
Journal:  Acta Psychiatr Scand       Date:  2000-10       Impact factor: 6.392

9.  The Chestnut Lodge follow-up study. III. Long-term outcome of borderline personalities.

Authors:  T H McGlashan
Journal:  Arch Gen Psychiatry       Date:  1986-01

10.  The longitudinal course of borderline psychopathology: 6-year prospective follow-up of the phenomenology of borderline personality disorder.

Authors:  Mary C Zanarini; Frances R Frankenburg; John Hennen; Kenneth R Silk
Journal:  Am J Psychiatry       Date:  2003-02       Impact factor: 18.112

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  80 in total

1.  Associations between changes in normal personality traits and borderline personality disorder symptoms over 16 years.

Authors:  Aidan G C Wright; Christopher J Hopwood; Mary C Zanarini
Journal:  Personal Disord       Date:  2014-11-03

2.  Functional outcomes in community-based adults with borderline personality disorder.

Authors:  Kristin N Javaras; Mary C Zanarini; James I Hudson; Shelly F Greenfield; John G Gunderson
Journal:  J Psychiatr Res       Date:  2017-01-24       Impact factor: 4.791

3.  Description and prediction of time-to-attainment of excellent recovery for borderline patients followed prospectively for 20 years.

Authors:  Mary C Zanarini; Christina M Temes; Frances R Frankenburg; D Bradford Reich; Garrett M Fitzmaurice
Journal:  Psychiatry Res       Date:  2018-02-20       Impact factor: 3.222

4.  Brain activation in response to overt and covert fear and happy faces in women with borderline personality disorder.

Authors:  Kathryn R Cullen; Lori L LaRiviere; Nathalie Vizueta; Kathleen M Thomas; Ruskin H Hunt; Michael J Miller; Kelvin O Lim; Sellman C Schulz
Journal:  Brain Imaging Behav       Date:  2016-06       Impact factor: 3.978

5.  Remnants and changes in facial emotion processing in women with remitted borderline personality disorder: an EEG study.

Authors:  Isabella Schneider; Katja Bertsch; Natalie A Izurieta Hidalgo; Laura E Müller; Christian Schmahl; Sabine C Herpertz
Journal:  Eur Arch Psychiatry Clin Neurosci       Date:  2017-09-27       Impact factor: 5.270

6.  Prediction of time-to-attainment of recovery for borderline patients followed prospectively for 16 years.

Authors:  M C Zanarini; F R Frankenburg; D B Reich; M M Wedig; L C Conkey; G M Fitzmaurice
Journal:  Acta Psychiatr Scand       Date:  2014-03-04       Impact factor: 6.392

7.  Levels of Acceptance and Forgiveness Reported by Patients With BPD and Personality-Disordered Comparison Subjects Over 20 Years of Prospective Follow-Up.

Authors:  Mary C Zanarini; Christina M Temes; Frances R Frankenburg; D Bradford Reich; Garrett M Fitzmaurice
Journal:  J Pers Disord       Date:  2019-01-16

8.  Relationship between sleep disturbance and recovery in patients with borderline personality disorder.

Authors:  David T Plante; Frances R Frankenburg; Garrett M Fitzmaurice; Mary C Zanarini
Journal:  J Psychosom Res       Date:  2013-02-11       Impact factor: 3.006

9.  Defense mechanisms reported by patients with borderline personality disorder and axis II comparison subjects over 16 years of prospective follow-up: description and prediction of recovery.

Authors:  Mary C Zanarini; Frances R Frankenburg; Garrett Fitzmaurice
Journal:  Am J Psychiatry       Date:  2013-01       Impact factor: 18.112

Review 10.  Problems in the boundaries of bipolar disorders.

Authors:  Joel Paris
Journal:  Curr Psychiatry Rep       Date:  2014-08       Impact factor: 5.285

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