OBJECTIVE: The syndromal and subsyndromal phenomenology of borderline personality disorder was tracked over 6 years of prospective follow-up. METHOD: The psychopathology of 362 inpatients with personality disorders was assessed with the Revised Diagnostic Interview for Borderlines (DIB-R) and borderline personality disorder module of the Revised Diagnostic Interview for DSM-III-R Personality Disorders. Of these patients, 290 met DIB-R and DSM-III-R criteria for borderline personality disorder and 72 met DSM-III-R criteria for other axis II disorders (and neither criteria set for borderline personality disorder). Most of the borderline patients received multiple treatments before the index admission and during the study. Over 94% of the total surviving subjects were reassessed at 2, 4, and 6 years by interviewers blind to previously collected information. RESULTS: Of the subjects with borderline personality disorder, 34.5% met the criteria for remission at 2 years, 49.4% at 4 years, 68.6% at 6 years, and 73.5% over the entire follow-up. Only 5.9% of those with remissions experienced recurrences. None of the comparison subjects with other axis II disorders developed borderline personality disorder during follow-up. The patients with borderline personality disorder had declining rates of 24 symptom patterns but remained symptomatically distinct from the comparison subjects. Impulsive symptoms resolved the most quickly, affective symptoms were the most chronic, and cognitive and interpersonal symptoms were intermediate. CONCLUSIONS: These results suggest that symptomatic improvement is both common and stable, even among the most disturbed borderline patients, and that the symptomatic prognosis for most, but not all, severely ill borderline patients is better than previously recognized.
OBJECTIVE: The syndromal and subsyndromal phenomenology of borderline personality disorder was tracked over 6 years of prospective follow-up. METHOD: The psychopathology of 362 inpatients with personality disorders was assessed with the Revised Diagnostic Interview for Borderlines (DIB-R) and borderline personality disorder module of the Revised Diagnostic Interview for DSM-III-R Personality Disorders. Of these patients, 290 met DIB-R and DSM-III-R criteria for borderline personality disorder and 72 met DSM-III-R criteria for other axis II disorders (and neither criteria set for borderline personality disorder). Most of the borderline patients received multiple treatments before the index admission and during the study. Over 94% of the total surviving subjects were reassessed at 2, 4, and 6 years by interviewers blind to previously collected information. RESULTS: Of the subjects with borderline personality disorder, 34.5% met the criteria for remission at 2 years, 49.4% at 4 years, 68.6% at 6 years, and 73.5% over the entire follow-up. Only 5.9% of those with remissions experienced recurrences. None of the comparison subjects with other axis II disorders developed borderline personality disorder during follow-up. The patients with borderline personality disorder had declining rates of 24 symptom patterns but remained symptomatically distinct from the comparison subjects. Impulsive symptoms resolved the most quickly, affective symptoms were the most chronic, and cognitive and interpersonal symptoms were intermediate. CONCLUSIONS: These results suggest that symptomatic improvement is both common and stable, even among the most disturbed borderline patients, and that the symptomatic prognosis for most, but not all, severely ill borderline patients is better than previously recognized.
Authors: Leslie C Morey; M Tracie Shea; John C Markowitz; Robert L Stout; Christopher J Hopwood; John G Gunderson; Carlos M Grilo; Thomas H McGlashan; Shirley Yen; Charles A Sanislow; Andrew E Skodol Journal: Am J Psychiatry Date: 2010-02-16 Impact factor: 18.112
Authors: David J Hellerstein; Andrew E Skodol; Eva Petkova; Hui Xie; John C Markowitz; Shirley Yen; John Gunderson; Carlos Grilo; Maria T Daversa; Thomas H McGlashan Journal: Compr Psychiatry Date: 2010-01-08 Impact factor: 3.735
Authors: John R Keefe; Barbara L Milrod; Robert Gallop; Jacques P Barber; Dianne L Chambless Journal: Depress Anxiety Date: 2017-12-06 Impact factor: 6.505
Authors: M C Zanarini; F R Frankenburg; D B Reich; M M Wedig; L C Conkey; G M Fitzmaurice Journal: Acta Psychiatr Scand Date: 2014-03-04 Impact factor: 6.392
Authors: Carlos M Grilo; Charles A Sanislow; John G Gunderson; Maria E Pagano; Shirley Yen; Mary C Zanarini; M Tracie Shea; Andrew E Skodol; Robert L Stout; Leslie C Morey; Thomas H McGlashan Journal: J Consult Clin Psychol Date: 2004-10