| Literature DB >> 22736543 |
Haja-Sherief N Musthafa1, Galina Dragneva, Line Lottonen, Mari Merentie, Lyubomir Petrov, Tommi Heikura, Elias Ylä-Herttuala, Seppo Ylä-Herttuala, Olli Gröhn, Timo Liimatainen.
Abstract
Longitudinal relaxation time in the rotating frame (T1ρ) was measured using continuous wave irradiation in normal and infarcted mouse myocardium in vivo. Significant increase in T1ρ was found after 7 days of infarction when compared with reference myocardium or in myocardium before infarction. Cine MRI and histology were performed to verify the severity of infarction. The time course of T1ρ in the infarct fits better with granulation and scar tissue formation than necrosis and edema. The results of the study show that T1ρ could potentially be a noninvasive quantitative marker for tissue remodeling after ischemic damage.Entities:
Mesh：
Year: 2012 PMID： 22736543 DOI： 10.1002/mrm.24382
Source DB: PubMed Journal: Magn Reson Med ISSN： 0740-3194 Impact factor: 4.668