Literature DB >> 22731649

Awareness and uptake of direct-to-consumer genetic testing among cancer cases, their relatives, and controls: the Northwest Cancer Genetics Network.

Taryn O Hall1, Anne D Renz, Katherine W Snapinn, Deborah J Bowen, Karen L Edwards.   

Abstract

AIMS: To determine if awareness of, interest in, and use of direct-to-consumer (DTC) genetic testing is greater in a sample of high-risk individuals (cancer cases and their relatives), compared to controls.
METHODS: Participants were recruited from the Northwest Cancer Genetics Network. A follow-up survey was mailed to participants to assess DTC genetic testing awareness, interest, and use.
RESULTS: One thousand two hundred sixty-seven participants responded to the survey. Forty-nine percent of respondents were aware of DTC genetic testing. Of those aware, 19% indicated interest in obtaining and <1% reported having used DTC genetic testing. Additional information supplied by respondents who reported use of DTC genetic tests indicated that 55% of these respondents likely engaged in clinical genetic testing, rather than DTC genetic testing.
CONCLUSION: Awareness of DTC genetic testing was greater in our sample of high-risk individuals than in controls and population-based studies. Although interest in and use of these tests among cases in our sample were equivalent to other population-based studies, interest in testing was higher among relatives and people who self-referred for a registry focused on cancer than among cases and controls. Additionally, our results suggest that there may be some confusion about what constitutes DTC genetic testing.

Entities:  

Mesh:

Year:  2012        PMID: 22731649      PMCID: PMC4077008          DOI: 10.1089/gtmb.2011.0235

Source DB:  PubMed          Journal:  Genet Test Mol Biomarkers        ISSN: 1945-0257


  11 in total

1.  Bioethical and clinical dilemmas of direct-to-consumer personal genomic testing: the problem of misattributed equivalence.

Authors:  Charis Eng; Richard R Sharp
Journal:  Sci Transl Med       Date:  2010-02-03       Impact factor: 17.956

2.  Letting the genome out of the bottle--will we get our wish?

Authors:  David J Hunter; Muin J Khoury; Jeffrey M Drazen
Journal:  N Engl J Med       Date:  2008-01-10       Impact factor: 91.245

3.  Public awareness and use of direct-to-consumer genetic tests: results from 3 state population-based surveys, 2006.

Authors:  Katrina A B Goddard; Debra Duquette; Amy Zlot; Jenny Johnson; Ann Annis-Emeott; Patrick W Lee; Mary Pat Bland; Karen L Edwards; Kristin Oehlke; Rebecca T Giles; Ann Rafferty; Michelle L Cook; Muin J Khoury
Journal:  Am J Public Health       Date:  2008-12-23       Impact factor: 9.308

4.  Social networkers' attitudes toward direct-to-consumer personal genome testing.

Authors:  Amy L McGuire; Christina M Diaz; Tao Wang; Susan G Hilsenbeck
Journal:  Am J Bioeth       Date:  2009       Impact factor: 11.229

5.  Interest in genetic testing for modest changes in breast cancer risk: implications for SNP testing.

Authors:  K D Graves; B N Peshkin; G Luta; W Tuong; M D Schwartz
Journal:  Public Health Genomics       Date:  2011-04-02       Impact factor: 2.000

6.  Consumers' use of web-based information and their decisions about multiplex genetic susceptibility testing.

Authors:  Kimberly A Kaphingst; Colleen M McBride; Christopher Wade; Sharon Hensley Alford; Lawrence C Brody; Andreas D Baxevanis
Journal:  J Med Internet Res       Date:  2010-09-29       Impact factor: 5.428

7.  The Cancer Genetics Network: recruitment results and pilot studies.

Authors:  Hoda Anton-Culver; Argyrios Ziogas; Deborah Bowen; Dianne Finkelstein; Constance Griffin; James Hanson; Claudine Isaacs; Carol Kasten-Sportes; Geraldine Mineau; Prakash Nadkarni; Barbara Rimer; Joellen Schildkraut; Louise Strong; Barbara Weber; Deborah Winn; Robert Hiatt; Susan Nayfield
Journal:  Community Genet       Date:  2003

8.  An unwelcome side effect of direct-to-consumer personal genome testing: raiding the medical commons.

Authors:  Amy L McGuire; Wylie Burke
Journal:  JAMA       Date:  2008-12-10       Impact factor: 56.272

9.  Health care provider and consumer awareness, perceptions, and use of direct-to-consumer personal genomic tests, United States, 2008.

Authors:  Katherine Kolor; Tiebin Liu; Jeanette St Pierre; Muin J Khoury
Journal:  Genet Med       Date:  2009-08       Impact factor: 8.822

10.  Size of the direct-to-consumer genomic testing market.

Authors:  Caroline F Wright; Shelley Gregory-Jones
Journal:  Genet Med       Date:  2010-09       Impact factor: 8.822

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  6 in total

1.  Factors Associated with Acceptability, Consideration and Intention of Uptake of Direct-To-Consumer Genetic Testing: A Survey Study.

Authors:  Kelly F J Stewart; Daša Kokole; Anke Wesselius; Annemie M W J Schols; Maurice P Zeegers; Hein de Vries; Liesbeth A D M van Osch
Journal:  Public Health Genomics       Date:  2018-10-25       Impact factor: 2.000

2.  Influence of individual differences in disease perception on consumer response to direct-to-consumer genomic testing.

Authors:  D L Boeldt; N J Schork; E J Topol; C S Bloss
Journal:  Clin Genet       Date:  2014-06-06       Impact factor: 4.438

3.  Direct-to-Consumer Genetic Testing and Personal Genomics Services: A Review of Recent Empirical Studies.

Authors:  J Scott Roberts; Jenny Ostergren
Journal:  Curr Genet Med Rep       Date:  2013-09

4.  Personalized Medicine Through SNP Testing for Breast Cancer Risk: Clinical Implementation.

Authors:  Rebecca Howe; Talya Miron-Shatz; Yaniv Hanoch; Zehra B Omer; Cristina O'Donoghue; Elissa M Ozanne
Journal:  J Genet Couns       Date:  2014-12-18       Impact factor: 2.537

5.  Attitudes towards personal genomics among older Swiss adults: An exploratory study.

Authors:  Laura Mählmann; Christina Röcke; Angela Brand; Ernst Hafen; Effy Vayena
Journal:  Appl Transl Genom       Date:  2016-02-01

Review 6.  Internet-Based Direct-to-Consumer Genetic Testing: A Systematic Review.

Authors:  Loredana Covolo; Sara Rubinelli; Elisabetta Ceretti; Umberto Gelatti
Journal:  J Med Internet Res       Date:  2015-12-14       Impact factor: 5.428

  6 in total

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