Literature DB >> 22729647

Expression, purification and functional reconstitution of slack sodium-activated potassium channels.

Yangyang Yan1, Youshan Yang, Shumin Bian, Fred J Sigworth.   

Abstract

The slack (slo2.2) gene codes for a potassium-channel α-subunit of the 6TM voltage-gated channel family. Expression of slack results in Na(+)-activated potassium channel activity in various cell types. We describe the purification and reconstitution of Slack protein and show that the Slack α-subunit alone is sufficient for potassium channel activity activated by sodium ions as assayed in planar bilayer membranes and in membrane vesicles.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22729647      PMCID： PMC3903048          DOI： 10.1007/s00232-012-9425-7

Source DB:  PubMed          Journal:  J Membr Biol        ISSN： 0022-2631            Impact factor:   1.843


  24 in total

1.  Formation of intermediate-conductance calcium-activated potassium channels by interaction of Slack and Slo subunits.

Authors:  W J Joiner; M D Tang; L Y Wang; S I Dworetzky; C G Boissard; L Gan; V K Gribkoff; L K Kaczmarek
Journal:  Nat Neurosci       Date:  1998-10       Impact factor: 24.884

2.  Localization of the Slack potassium channel in the rat central nervous system.

Authors:  Arin Bhattacharjee; Li Gan; Leonard K Kaczmarek
Journal:  J Comp Neurol       Date:  2002-12-16       Impact factor: 3.215

3.  Single particle analysis at high resolution.

Authors:  Yao Cong; Steven J Ludtke
Journal:  Methods Enzymol       Date:  2010       Impact factor: 1.600

4.  The sodium-activated potassium channel is encoded by a member of the Slo gene family.

Authors:  Alex Yuan; Celia M Santi; Aguan Wei; Zhao Wen Wang; Kelly Pollak; Michael Nonet; Leonard Kaczmarek; C Michael Crowder; Lawrence Salkoff
Journal:  Neuron       Date:  2003-03-06       Impact factor: 17.173

5.  Intracellular Na+ activates a K+ channel in mammalian cardiac cells.

Authors:  M Kameyama; M Kakei; R Sato; T Shibasaki; H Matsuda; H Irisawa
Journal:  Nature       Date:  1984 May 24-30       Impact factor: 49.962

6.  The RCK2 domain uses a coordination site present in Kir channels to confer sodium sensitivity to Slo2.2 channels.

Authors:  Zhe Zhang; Avia Rosenhouse-Dantsker; Qiong-Yao Tang; Sergei Noskov; Diomedes E Logothetis
Journal:  J Neurosci       Date:  2010-06-02       Impact factor: 6.167

7.  Slo2 sodium-activated K+ channels bind to the PDZ domain of PSD-95.

Authors:  Shigeo Uchino; Hidenori Wada; Shizuyo Honda; Takae Hirasawa; Shigeki Yanai; Yasuko Nakamura; Yumiko Ondo; Shinichi Kohsaka
Journal:  Biochem Biophys Res Commun       Date:  2003-10-31       Impact factor: 3.575

8.  Fragile X mental retardation protein controls gating of the sodium-activated potassium channel Slack.

Authors:  Maile R Brown; Jack Kronengold; Valeswara-Rao Gazula; Yi Chen; John G Strumbos; Fred J Sigworth; Dhasakumar Navaratnam; Leonard K Kaczmarek
Journal:  Nat Neurosci       Date:  2010-05-30       Impact factor: 24.884

9.  Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution.

Authors:  Peng Yuan; Manuel D Leonetti; Alexander R Pico; Yichun Hsiung; Roderick MacKinnon
Journal:  Science       Date:  2010-05-27       Impact factor: 47.728

10.  Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy.

Authors:  Liguo Wang; Fred J Sigworth
Journal:  Nature       Date:  2009-08-30       Impact factor: 49.962
View more
  8 in total

1.  Identification of the Intracellular Na+ Sensor in Slo2.1 Potassium Channels.

Authors:  Steven J Thomson; Angela Hansen; Michael C Sanguinetti
Journal:  J Biol Chem       Date:  2015-04-22       Impact factor: 5.157

2.  Hydrophobic interactions between the S5 segment and the pore helix stabilizes the closed state of Slo2.1 potassium channels.

Authors:  Tomoyuki Suzuki; Angela Hansen; Michael C Sanguinetti
Journal:  Biochim Biophys Acta       Date:  2015-12-23

3.  Structural Titration of Slo2.2, a Na+-Dependent K+ Channel.

Authors:  Richard K Hite; Roderick MacKinnon
Journal:  Cell       Date:  2017-01-19       Impact factor: 41.582

4.  SCN10A/Nav1.8 modulation of peak and late sodium currents in patients with early onset atrial fibrillation.

Authors:  Eleonora Savio-Galimberti; Peter Weeke; Raafia Muhammad; Marcia Blair; Sami Ansari; Laura Short; Thomas C Atack; Kaylen Kor; Carlos G Vanoye; Morten Salling Olesen; Tao Yang; Alfred L George; Dan M Roden; Dawood Darbar
Journal:  Cardiovasc Res       Date:  2014-07-22       Impact factor: 10.787

5.  Cryo-electron microscopy structure of the Slo2.2 Na(+)-activated K(+) channel.

Authors:  Richard K Hite; Peng Yuan; Zongli Li; Yichun Hsuing; Thomas Walz; Roderick MacKinnon
Journal:  Nature       Date:  2015-10-05       Impact factor: 49.962

6.  Lipid droplets and autophagosomes together with chaperones fine-tune expression of SGK1.

Authors:  Madiha J Ghani; Wenxue Gu; Zhuyuan Chen; Cecilia M Canessa
Journal:  J Cell Mol Med       Date:  2022-04-08       Impact factor: 5.295

7.  Structural basis of ion permeation gating in Slo2.1 K+ channels.

Authors:  Priyanka Garg; Alison Gardner; Vivek Garg; Michael C Sanguinetti
Journal:  J Gen Physiol       Date:  2013-11       Impact factor: 4.086

8.  Activation of a nucleotide-dependent RCK domain requires binding of a cation cofactor to a conserved site.

Authors:  Celso M Teixeira-Duarte; Fátima Fonseca; João H Morais-Cabral
Journal:  Elife       Date:  2019-12-23       Impact factor: 8.140
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.