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Literature DB >> 2272918

The structure of PA48009: the revised structure of duramycin.

F Hayashi¹, K Nagashima, Y Terui, Y Kawamura, K Matsumoto, H Itazaki.

Abstract

PA48009, a lanthionine-containing peptide antibiotic was isolated from the culture broth of Streptoverticillium griseoverticillatum PA-48009, and identified as duramycin. Determination of the structure using both Edman degradations and 2D NMR spectroscopy showed the need to revise the structure of duramycin given in literature. Duramycin (PA48009) was different from lanthiopeptin (Ro 09-0198, cinnamycin) only by a Lys/Arg exchange at position 2.

Entities: Chemical Species

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Year: 1990 PMID： 2272918 DOI： 10.7164/antibiotics.43.1421

Source DB: PubMed Journal: J Antibiot (Tokyo) ISSN： 0021-8820 Impact factor: 2.649

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Cited

19 in total

1. Whole-body imaging of high-dose ionizing irradiation-induced tissue injuries using 99mTc-duramycin.

Authors: Steven E Johnson; Zhixin Li; Yu Liu; John E Moulder; Ming Zhao
Journal: J Nucl Med Date: 2013-06-26 Impact factor: 10.057

2. Understanding the in vivo uptake kinetics of a phosphatidylethanolamine-binding agent (99m)Tc-Duramycin.

Authors: Said Audi; Zhixin Li; Joseph Capacete; Yu Liu; Wei Fang; Laura G Shu; Ming Zhao
Journal: Nucl Med Biol Date: 2012-04-23 Impact factor: 2.408

Review 3. Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.

Authors: Lindsay M Repka; Jonathan R Chekan; Satish K Nair; Wilfred A van der Donk
Journal: Chem Rev Date: 2017-01-30 Impact factor: 60.622

Review 4. Lantibiotics as probes for phosphatidylethanolamine.

Authors: Ming Zhao
Journal: Amino Acids Date: 2009-11-22 Impact factor: 3.520

5. The feasibility of imaging myocardial ischemic/reperfusion injury using (99m)Tc-labeled duramycin in a porcine model.

Authors: Lei Wang; Feng Wang; Wei Fang; Steven E Johnson; Said Audi; Michael Zimmer; Thomas A Holly; Daniel C Lee; Bao Zhu; Haibo Zhu; Ming Zhao
Journal: Nucl Med Biol Date: 2014-09-23 Impact factor: 2.408

6. Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.

Authors: John G Ondeykal; Kithsiri B Herath; Hiranthi Jayasuriya; Jon D Polishook; Gerald F Bills; Anne W Dombrowski; Marina Mojena; Gregory Koch; Jerry DiSalvo; Julie DeMartino; Ziqiang Guan; Weerachai Nanakorn; Cori M Morenberg; Michael J Balick; Dennis W Stevenson; Marc Slattery; Robert P Borris; Sheo B Singh
Journal: Mol Divers Date: 2005 Impact factor: 2.943

The structure of PA48009: the revised structure of duramycin.

1. Whole-body imaging of high-dose ionizing irradiation-induced tissue injuries using 99mTc-duramycin.

2. Understanding the in vivo uptake kinetics of a phosphatidylethanolamine-binding agent (99m)Tc-Duramycin.

Review 3. Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes.

Review 4. Lantibiotics as probes for phosphatidylethanolamine.

5. The feasibility of imaging myocardial ischemic/reperfusion injury using (99m)Tc-labeled duramycin in a porcine model.

6. Discovery of structurally diverse natural product antagonists of chemokine receptor CXCR3.

7. Insights into the Biosynthesis of Duramycin.

8. Curvature-dependent recognition of ethanolamine phospholipids by duramycin and cinnamycin.

Review 9. Ribosomal peptide natural products: bridging the ribosomal and nonribosomal worlds.

10. Biomarkers for Radiation Pneumonitis Using Noninvasive Molecular Imaging.