| Literature DB >> 2272757 |
K Noda1, M Oda, M Sato, N Yoshida.
Abstract
A series of p-nitroanilides of t-butyloxycarbonylamino acids, including Boc-Trp, Boc-Asn, Boc-Gln, Boc-Ser(But), Boc-Thr(But), Boc-Asp(OBut), Boc-Lys(TFA), and Boc-His(Boc), were prepared conveniently by the mixed anhydride method using 2,2-dimethylpropanoic chloride (pivaloyl chloride). The products were obtained in 40-60% yields after purification by column chromatography on Sephadex LH-20. p-Nitroanilide of histidine was purified after deprotection of Boc-His(Boc)-pNA and obtained as H-His-pNA.2HCl.Entities:
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Year: 1990 PMID： 2272757 DOI： 10.1111/j.1399-3011.1990.tb00967.x
Source DB: PubMed Journal: Int J Pept Protein Res ISSN： 0367-8377