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Literature DB >> 22723221

Assessing cell and organ senescence biomarkers.

Bruno Bernardes de Jesus¹, Maria A Blasco.

Abstract

A major goal in cancer and aging research is to discriminate the biochemical modifications that happen locally that could account for the healthiness or malignancy of tissues. Senescence is one general antiproliferative cellular process that acts as a strong barrier for cancer progression, playing a crucial role in aging. Here, we focus on the current methods to assess cellular senescence, discriminating the advantages and disadvantages of several senescence biomarkers.

Entities: Chemical Disease Gene Mutation Species

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Year: 2012 PMID： 22723221 PMCID： PMC4824275 DOI： 10.1161/CIRCRESAHA.111.247866

Source DB: PubMed Journal: Circ Res ISSN： 0009-7330 Impact factor: 17.367

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