Literature DB >> 22722750

Mutations in the DNMT3A exon 23 independently predict poor outcome in older patients with acute myeloid leukemia: a SWOG report.

F Ostronoff, M Othus, P A Ho, M Kutny, D E Geraghty, S H Petersdorf, J E Godwin, C L Willman, J P Radich, F R Appelbaum, D L Stirewalt, S Meshinchi.   

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Year:  2012        PMID： 22722750      PMCID： PMC4457316          DOI： 10.1038/leu.2012.168

Source DB:  PubMed          Journal:  Leukemia        ISSN： 0887-6924            Impact factor:   11.528


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  18 in total

1.  DNMT3A mutations in acute myeloid leukemia: stability during disease evolution and clinical implications.

Authors:  Hsin-An Hou; Yuan-Yeh Kuo; Chieh-Yu Liu; Wen-Chien Chou; Ming Cheng Lee; Chien-Yuan Chen; Liang-In Lin; Mei-Hsuan Tseng; Chi-Fei Huang; Ying-Chieh Chiang; Fen-Yu Lee; Ming-Chih Liu; Chia-Wen Liu; Jih-Luh Tang; Ming Yao; Shang-Yi Huang; Bor-Sheng Ko; Szu-Chun Hsu; Shang-Ju Wu; Woei Tsay; Yao-Chang Chen; Hwei-Fang Tien
Journal:  Blood       Date:  2011-11-10       Impact factor: 22.113

2.  Gene mutation patterns and their prognostic impact in a cohort of 1185 patients with acute myeloid leukemia.

Authors:  Yang Shen; Yong-Mei Zhu; Xing Fan; Jing-Yi Shi; Qin-Rong Wang; Xiao-Jing Yan; Zhao-Hui Gu; Yan-Yan Wang; Bing Chen; Chun-Lei Jiang; Han Yan; Fei-Fei Chen; Hai-Min Chen; Zhu Chen; Jie Jin; Sai-Juan Chen
Journal:  Blood       Date:  2011-08-31       Impact factor: 22.113

3.  Incidence and prognostic influence of DNMT3A mutations in acute myeloid leukemia.

Authors:  Felicitas Thol; Frederik Damm; Andrea Lüdeking; Claudia Winschel; Katharina Wagner; Michael Morgan; Haiyang Yun; Gudrun Göhring; Brigitte Schlegelberger; Dieter Hoelzer; Michael Lübbert; Lothar Kanz; Walter Fiedler; Hartmut Kirchner; Gerhard Heil; Jürgen Krauter; Arnold Ganser; Michael Heuser
Journal:  J Clin Oncol       Date:  2011-06-13       Impact factor: 44.544

4.  Analysis of FLT3-activating mutations in 979 patients with acute myelogenous leukemia: association with FAB subtypes and identification of subgroups with poor prognosis.

Authors:  Christian Thiede; Christine Steudel; Brigitte Mohr; Markus Schaich; Ulrike Schäkel; Uwe Platzbecker; Martin Wermke; Martin Bornhäuser; Markus Ritter; Andreas Neubauer; Gerhard Ehninger; Thomas Illmer
Journal:  Blood       Date:  2002-06-15       Impact factor: 22.113

5.  Age-related prognostic impact of different types of DNMT3A mutations in adults with primary cytogenetically normal acute myeloid leukemia.

Authors:  Guido Marcucci; Klaus H Metzeler; Sebastian Schwind; Heiko Becker; Kati Maharry; Krzysztof Mrózek; Michael D Radmacher; Jessica Kohlschmidt; Deedra Nicolet; Susan P Whitman; Yue-Zhong Wu; Bayard L Powell; Thomas H Carter; Jonathan E Kolitz; Meir Wetzler; Andrew J Carroll; Maria R Baer; Joseph O Moore; Michael A Caligiuri; Richard A Larson; Clara D Bloomfield
Journal:  J Clin Oncol       Date:  2012-01-30       Impact factor: 44.544

6.  Karyotypic analysis predicts outcome of preremission and postremission therapy in adult acute myeloid leukemia: a Southwest Oncology Group/Eastern Cooperative Oncology Group Study.

Authors:  M L Slovak; K J Kopecky; P A Cassileth; D H Harrington; K S Theil; A Mohamed; E Paietta; C L Willman; D R Head; J M Rowe; S J Forman; F R Appelbaum
Journal:  Blood       Date:  2000-12-15       Impact factor: 22.113

7.  Exome sequencing identifies somatic mutations of DNA methyltransferase gene DNMT3A in acute monocytic leukemia.

Authors:  Xiao-Jing Yan; Jie Xu; Zhao-Hui Gu; Chun-Ming Pan; Gang Lu; Yang Shen; Jing-Yi Shi; Yong-Mei Zhu; Lin Tang; Xiao-Wei Zhang; Wen-Xue Liang; Jian-Qing Mi; Huai-Dong Song; Ke-Qin Li; Zhu Chen; Sai-Juan Chen
Journal:  Nat Genet       Date:  2011-03-13       Impact factor: 38.330

8.  Outcome after induction chemotherapy for older patients with acute myeloid leukemia is not improved with mitoxantrone and etoposide compared to cytarabine and daunorubicin: a Southwest Oncology Group study.

Authors:  Jeanne E Anderson; Kenneth J Kopecky; Cheryl L Willman; David Head; Margaret R O'Donnell; Frederick W Luthardt; Thomas H Norwood; I-Ming Chen; Stanley P Balcerzak; David B Johnson; Frederick R Appelbaum
Journal:  Blood       Date:  2002-08-01       Impact factor: 22.113

9.  Recurrent DNMT3A R882 mutations in Chinese patients with acute myeloid leukemia and myelodysplastic syndrome.

Authors:  Jiang Lin; Dong-ming Yao; Jun Qian; Qin Chen; Wei Qian; Yun Li; Jing Yang; Cui-zhu Wang; Hai-yan Chai; Zhen Qian; Gao-fei Xiao; Wen-rong Xu
Journal:  PLoS One       Date:  2011-10-31       Impact factor: 3.240

10.  Leukemic mutations in the methylation-associated genes DNMT3A and IDH2 are rare events in pediatric AML: a report from the Children's Oncology Group.

Authors:  Phoenix A Ho; Matthew A Kutny; Todd A Alonzo; Robert B Gerbing; Jason Joaquin; Susana C Raimondi; Alan S Gamis; Soheil Meshinchi
Journal:  Pediatr Blood Cancer       Date:  2011-04-18       Impact factor: 3.838
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  23 in total

1.  DNMT3A mutant transcript levels persist in remission and do not predict outcome in patients with acute myeloid leukemia.

Authors:  V I Gaidzik; D Weber; P Paschka; A Kaumanns; S Krieger; A Corbacioglu; J Krönke; S Kapp-Schwoerer; D Krämer; H-A Horst; I Schmidt-Wolf; G Held; A Kündgen; M Ringhoffer; K Götze; T Kindler; W Fiedler; M Wattad; R F Schlenk; L Bullinger; V Teleanu; B Schlegelberger; F Thol; M Heuser; A Ganser; H Döhner; K Döhner
Journal:  Leukemia       Date:  2017-06-23       Impact factor: 11.528

Review 2.  The de novo DNA methyltransferase DNMT3A in development and cancer.

Authors:  Bi-Feng Chen; Wai-Yee Chan
Journal:  Epigenetics       Date:  2014-03-03       Impact factor: 4.528

Review 3.  Genomic tools in acute myeloid leukemia: From the bench to the bedside.

Authors:  Brian S White; John F DiPersio
Journal:  Cancer       Date:  2014-01-28       Impact factor: 6.860

Review 4.  Treatment ethics, quality of life and health economics in the management of hematopoietic malignancies in older patients.

Authors:  H J Deeg
Journal:  Bone Marrow Transplant       Date:  2015-06-08       Impact factor: 5.483

5.  DNMT3A mutations promote anthracycline resistance in acute myeloid leukemia via impaired nucleosome remodeling.

Authors:  Olga A Guryanova; Kaitlyn Shank; Barbara Spitzer; Luisa Luciani; Richard P Koche; Francine E Garrett-Bakelman; Chezi Ganzel; Benjamin H Durham; Abhinita Mohanty; Gregor Hoermann; Sharon A Rivera; Alan G Chramiec; Elodie Pronier; Lennart Bastian; Matthew D Keller; Daniel Tovbin; Evangelia Loizou; Abby R Weinstein; Adriana Rodriguez Gonzalez; Yen K Lieu; Jacob M Rowe; Friederike Pastore; Anna Sophia McKenney; Andrei V Krivtsov; Wolfgang R Sperr; Justin R Cross; Christopher E Mason; Martin S Tallman; Maria E Arcila; Omar Abdel-Wahab; Scott A Armstrong; Stefan Kubicek; Philipp B Staber; Mithat Gönen; Elisabeth M Paietta; Ari M Melnick; Stephen D Nimer; Siddhartha Mukherjee; Ross L Levine
Journal:  Nat Med       Date:  2016-11-14       Impact factor: 53.440

Review 6.  DNMT3A in haematological malignancies.

Authors:  Liubin Yang; Rachel Rau; Margaret A Goodell
Journal:  Nat Rev Cancer       Date:  2015-02-19       Impact factor: 60.716

7.  Prognostic significance of NPM1 mutations in the absence of FLT3-internal tandem duplication in older patients with acute myeloid leukemia: a SWOG and UK National Cancer Research Institute/Medical Research Council report.

Authors:  Fabiana Ostronoff; Megan Othus; Michelle Lazenby; Elihu Estey; Frederick R Appelbaum; Anna Evans; John Godwin; Amanda Gilkes; Kenneth J Kopecky; Alan Burnett; Alan F List; Min Fang; Vivian G Oehler; Stephen H Petersdorf; Era L Pogosova-Agadjanyan; Jerald P Radich; Cheryl L Willman; Soheil Meshinchi; Derek L Stirewalt
Journal:  J Clin Oncol       Date:  2015-02-23       Impact factor: 44.544

8.  Bone marrow transplantation and acute myeloid leukemia: Brazilian guidelines.

Authors:  Lucia Mariano da Rocha Silla; Frederico Dulley; Rosaura Saboya; Eduardo Paton; Fabio Kerbauy; Adriano de Moraes Arantes; Nelson Hamerschlak
Journal:  Rev Bras Hematol Hemoter       Date:  2013

9.  The prognostic significance of IRF8 transcripts in adult patients with acute myeloid leukemia.

Authors:  Era L Pogosova-Agadjanyan; Kenneth J Kopecky; Fabiana Ostronoff; Frederick R Appelbaum; John Godwin; Hana Lee; Alan F List; Jennifer J May; Vivian G Oehler; Steve Petersdorf; Galina L Pogosov; Jerald P Radich; Cheryl L Willman; Soheil Meshinchi; Derek L Stirewalt
Journal:  PLoS One       Date:  2013-08-14       Impact factor: 3.240

Review 10.  DNMT3A and IDH mutations in acute myeloid leukemia and other myeloid malignancies: associations with prognosis and potential treatment strategies.

Authors:  A P Im; A R Sehgal; M P Carroll; B D Smith; A Tefferi; D E Johnson; M Boyiadzis
Journal:  Leukemia       Date:  2014-04-04       Impact factor: 12.883
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