AIM: To investigate the reliability of massive hepatectomy models by using clip techniques. METHODS: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings. RESULTS: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques. CONCLUSION: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data.
AIM: To investigate the reliability of massive hepatectomy models by using clip techniques. METHODS: We analyzed anatomical findings in 100 mice following massive hepatectomy induced by liver reduction > 70%. The impact of various factors in the different models was also analyzed, including learning curves, operative time, survival curves, and histopathological findings. RESULTS: According to anatomical results, models with 75%, 80%, and 90% hepatectomy produced massive hepatectomy. Learning curves and operative times were most optimal with the clip technique. Each hepatectomy performed using the clip technique produced a reasonable survival curve, and there were no differences in histopathological findings between the suture and clip techniques. CONCLUSION: Massive hepatectomy by the clip technique is simple and can provide reliable and relevant data.
Authors: Daniel Inderbitzin; Peter Studer; Daniel Sidler; Guido Beldi; Valentin Djonov; Adrian Keogh; Daniel Candinas Journal: Microsurgery Date: 2006 Impact factor: 2.425
Authors: P Sánchez-Velázquez; Q Castellví; A Villanueva; R Quesada; C Pañella; M Cáceres; D Dorcaratto; A Andaluz; X Moll; M Trujillo; J M Burdío; E Berjano; L Grande; A Ivorra; F Burdío Journal: Sci Rep Date: 2016-04-01 Impact factor: 4.379