Literature DB >> 22715465

Imaging histamine in live basophils and macrophages with a fluorescent mesoionic acid fluoride.

Nicola Kielland1, Marc Vendrell, Rodolfo Lavilla, Young-Tae Chang.   

Abstract

Histamine is a biogenic amine with fundamental roles in circulatory and immune systems. We report a fluorescent small molecule (Histamine Blue) for imaging intracellular histamine in live basophils and macrophages. Histamine Blue is a fluorescent mesoionic acid fluoride that turns on upon reaction with histamine. The selective response of Histamine Blue enabled the visualization of intracellular histamine under different physiological conditions.

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Year:  2012        PMID： 22715465     DOI： 10.1039/c2cc32292g

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  9 in total

1.  SCOTfluors: Small, Conjugatable, Orthogonal, and Tunable Fluorophores for In Vivo Imaging of Cell Metabolism.

Authors:  Sam Benson; Antonio Fernandez; Nicole D Barth; Fabio de Moliner; Mathew H Horrocks; C Simon Herrington; Jose Luis Abad; Antonio Delgado; Lisa Kelly; Ziyuan Chang; Yi Feng; Miyako Nishiura; Yuichiro Hori; Kazuya Kikuchi; Marc Vendrell
Journal:  Angew Chem Int Ed Engl       Date:  2019-04-12       Impact factor: 15.336

2.  N-Hydroxybenzimidazole as a structurally modifiable platform for N-oxyl radicals for direct C-H functionalization reactions.

Authors:  Tomomi Yoshii; Saori Tsuzuki; Shunya Sakurai; Ryu Sakamoto; Julong Jiang; Miho Hatanaka; Akira Matsumoto; Keiji Maruoka
Journal:  Chem Sci       Date:  2020-05-18       Impact factor: 9.825

3.  Multicomponent reactions for de novo synthesis of BODIPY probes: in vivo imaging of phagocytic macrophages.

Authors:  Ana Vázquez-Romero; Nicola Kielland; María J Arévalo; Sara Preciado; Richard J Mellanby; Yi Feng; Rodolfo Lavilla; Marc Vendrell
Journal:  J Am Chem Soc       Date:  2013-10-16       Impact factor: 15.419

Review 4.  Modern Synthetic Avenues for the Preparation of Functional Fluorophores.

Authors:  Fabio de Moliner; Nicola Kielland; Rodolfo Lavilla; Marc Vendrell
Journal:  Angew Chem Int Ed Engl       Date:  2017-02-17       Impact factor: 15.336

5.  Quinone-Derived π-Extended Phenazines as New Fluorogenic Probes for Live-Cell Imaging of Lipid Droplets.

Authors:  Fabio de Moliner; Aaron King; Gleiston G Dias; Guilherme F de Lima; Carlos A de Simone; Eufrânio N da Silva Júnior; Marc Vendrell
Journal:  Front Chem       Date:  2018-08-13       Impact factor: 5.221

6.  Development of a histamine aptasensor for food safety monitoring.

Authors:  Mohammed Dwidar; Yohei Yokobayashi
Journal:  Sci Rep       Date:  2019-11-13       Impact factor: 4.379

7.  A Functional Chemiluminescent Probe for in Vivo Imaging of Natural Killer Cell Activity Against Tumours.

Authors:  Jamie I Scott; Sara Gutkin; Ori Green; Emily J Thompson; Takanori Kitamura; Doron Shabat; Marc Vendrell
Journal:  Angew Chem Int Ed Engl       Date:  2021-02-02       Impact factor: 15.336

Review 8.  Heterocycle-Based Multicomponent Reactions in Drug Discovery: From Hit Finding to Rational Design.

Authors:  Pau Nadal Rodríguez; Ouldouz Ghashghaei; Andrea Bagán; Carmen Escolano; Rodolfo Lavilla
Journal:  Biomedicines       Date:  2022-06-23

9.  Tricarbocyanine N-triazoles: the scaffold-of-choice for long-term near-infrared imaging of immune cells in vivo.

Authors:  Richard J Mellanby; Jamie I Scott; Iris Mair; Antonio Fernandez; Louise Saul; Jochen Arlt; Monica Moral; Marc Vendrell
Journal:  Chem Sci       Date:  2018-08-08       Impact factor: 9.825
  9 in total

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