Literature DB >> 22712743

The use of animal as models: ethical considerations.

Neil Levy1.   

Abstract

The use of animals in scientific research is highly controversial. Older justifications, which referred to an immense gulf between human beings and other animals, can no longer be sustained in the face of a large body of scientific evidence concerning the similarities between human beings and other animals. The probability is very high that they are like us in many important ways, including in having a capacity to suffer. Because animals may suffer during research, their use must be justified. An appropriate justification will require that researchers can demonstrate that the expected benefits of the research, in terms of pure knowledge and medical applications, outweigh the suffering imposed. However, while the infliction of suffering on animal models must meet stringent conditions, research which involves the (painless) death of animals is often easier to justify, since few animals other than human beings possess the psychological capacities required to care about their future.
© 2012 The Author. International Journal of Stroke © 2012 World Stroke Organization.

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Year:  2012        PMID: 22712743     DOI: 10.1111/j.1747-4949.2012.00772.x

Source DB:  PubMed          Journal:  Int J Stroke        ISSN: 1747-4930            Impact factor:   5.266


  10 in total

Review 1.  3D in vitro modeling of the central nervous system.

Authors:  Amy M Hopkins; Elise DeSimone; Karolina Chwalek; David L Kaplan
Journal:  Prog Neurobiol       Date:  2014-11-22       Impact factor: 11.685

2.  Remote vitals monitoring in rodents using video recordings.

Authors:  Janosch Kunczik; Carina Barbosa Pereira; Leonie Zieglowski; René Tolba; Laura Wassermann; Christine Häger; André Bleich; Heike Janssen; Thomas Thum; Michael Czaplik
Journal:  Biomed Opt Express       Date:  2019-08-05       Impact factor: 3.732

3.  Disodium Cromolyn and Anti-podoplanin Antibodies Strongly Inhibit Growth of BHK 21/C13-derived Fibrosarcoma in a Chick Embryo Chorioallantoic Membrane Model.

Authors:  Anca Maria Cimpean; Dusan Lalošević; Vesna Lalošević; Pavle Banović; Marius Raica; Ovidiu Alexandru Mederle
Journal:  In Vivo       Date:  2018 Jul-Aug       Impact factor: 2.155

4.  Patient-Specific 3D Bioprinted Models of Developing Human Heart.

Authors:  Alexander D Cetnar; Martin L Tomov; Liqun Ning; Bowen Jing; Andrea S Theus; Akaash Kumar; Amanda N Wijntjes; Sai Raviteja Bhamidipati; Katherine Pham Do; Athanasios Mantalaris; John N Oshinski; Reza Avazmohammadi; Brooks D Lindsey; Holly D Bauser-Heaton; Vahid Serpooshan
Journal:  Adv Healthc Mater       Date:  2020-12-04       Impact factor: 11.092

5.  Indigenous Inexpensive Practice Models for Skill Development in Neuroendoscopy.

Authors:  Jitin Bajaj; Yad Ram Yadav; Anurag Pateriya; Vijay Parihar; Shailendra Ratre; Amitesh Dubey
Journal:  J Neurosci Rural Pract       Date:  2017 Apr-Jun

Review 6.  Bioactive Glasses: Where Are We and Where Are We Going?

Authors:  Francesco Baino; Sepideh Hamzehlou; Saeid Kargozar
Journal:  J Funct Biomater       Date:  2018-03-19

7.  Pharmacological effects of berberine on models of ulcerative colitis: A meta-analysis and systematic review of animal studies.

Authors:  Shuangyuan Hu; Pengfei Wei; Wei Li; Qingsong Liu; Shuanglan Chen; Caiyu Hu; Xiaochuan Guo; Xiao Ma; Jinhao Zeng; Yi Zhang
Journal:  Front Pharmacol       Date:  2022-09-06       Impact factor: 5.988

Review 8.  Towards clinical management of traumatic brain injury: a review of models and mechanisms from a biomechanical perspective.

Authors:  Dhananjay R Namjoshi; Craig Good; Wai Hang Cheng; William Panenka; Darrin Richards; Peter A Cripton; Cheryl L Wellington
Journal:  Dis Model Mech       Date:  2013-09-12       Impact factor: 5.758

Review 9.  Silkworm: A Promising Model Organism in Life Science.

Authors:  Xu Meng; Feifei Zhu; Keping Chen
Journal:  J Insect Sci       Date:  2017-09-01       Impact factor: 1.857

10.  Remote Welfare Monitoring of Rodents Using Thermal Imaging.

Authors:  Carina Barbosa Pereira; Janosch Kunczik; Leonie Zieglowski; René Tolba; Ahmed Abdelrahman; Dietmar Zechner; Brigitte Vollmar; Heike Janssen; Thomas Thum; Michael Czaplik
Journal:  Sensors (Basel)       Date:  2018-10-28       Impact factor: 3.576

  10 in total

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