Literature DB >> 22712028

Exercise and Cancer Treatment Symptoms in 408 Newly Diagnosed Older Cancer Patients.

Lisa K Sprod1, Supriya G Mohile, Wendy Demark-Wahnefried, Michelle C Janelsins, Luke J Peppone, Gary R Morrow, Raymond Lord, Howard Gross, Karen M Mustian.   

Abstract

While the benefits of exercise for managing cancer-and treatment-related side effects has been shown among various populations of cancer survivors, a relative dearth of information exists among older cancer patients.
OBJECTIVES: To determine the prevalence of exercise participation during and after primary cancer treatment in older (≥65 years) and the oldest (≥80 years) cancer patients and to examine the relationships between exercise, symptoms, and self-rated health (SRH).
MATERIALS AND METHODS: 408 newly diagnosed older cancer patients (mean age=73, range=65-92) scheduled to receive chemotherapy and/or radiation therapy reported symptoms and SRH prior to, during, and 6 months after treatment, and exercise participation during and following treatment.
RESULTS: Forty-six percent of older and 41% of the oldest patients reported exercising during treatment. Sixty percent of older and 68% of the oldest patients reported exercising in the 6 months thereafter. Older patients who exercised during treatment reported less shortness of breath and better SRH during treatment, and better SRH following treatment. The oldest patients who exercised during treatment reported less memory loss and better SRH during treatment and less fatigue and better SRH following treatment. The oldest patients who exercised following treatment reported less fatigue, skin problems, and total symptom burden following treatment.
CONCLUSION: These data suggest a willingness of older cancer patients to attempt exercise during and after treatment. Exercise during these times is associated with less severe symptoms; further clinical research examining the efficacy of formal exercise interventions to reduce symptoms and improve SRH in older cancer patients is needed.

Entities:  

Year:  2012        PMID: 22712028      PMCID: PMC3376161          DOI: 10.1016/j.jgo.2012.01.002

Source DB:  PubMed          Journal:  J Geriatr Oncol        ISSN: 1879-4068            Impact factor:   3.599


  46 in total

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2.  Decline of physical and cognitive conditions in the elderly measured through the functional reach test and the mini-mental state examination.

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Review 4.  Physical exercise in cancer patients during and after medical treatment: a systematic review of randomized and controlled clinical trials.

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8.  Lifestyle intervention development study to improve physical function in older adults with cancer: outcomes from Project LEAD.

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2.  Novel physical activity interventions for older patients with prostate cancer on hormone therapy: A pilot randomized study.

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Review 3.  Exercise Recommendations for the Management of Symptoms Clusters Resulting From Cancer and Cancer Treatments.

Authors:  Karen M Mustian; Calvin L Cole; Po Ju Lin; Matt Asare; Chunkit Fung; Michelle C Janelsins; Charles S Kamen; Luke J Peppone; Allison Magnuson
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Review 6.  Prevalence, mechanisms, and management of cancer-related cognitive impairment.

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7.  Qigong intervention for breast cancer survivors with complaints of decreased cognitive function.

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9.  Cognition and Cognitive Impairment in Older Adults with Cancer.

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Review 10.  Exercise and Physical Activity in Patients with Osteosarcoma and Survivors.

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