| Literature DB >> 22704203 |
Andrey A Toropov1, Alla P Toropova, Emilio Benfenati, Giuseppina Gini, Tomasz Puzyn, Danuta Leszczynska, Jerzy Leszczynski.
Abstract
Convenient to apply and available on the Internet software CORAL (http://www.insilico.eu/CORAL) has been used to build up quantitative structure-activity relationships (QSAR) for prediction of cytotoxicity of metal oxide nanoparticles to bacteria Escherichia coli (minus logarithm of concentration for 50% effect pEC50). In this study six random splits of the data into the training and test set were examined. It has been shown that the CORAL provides a reliable tool that could be used to build up a QSAR of the pEC50.Entities:
Mesh：
Substances：
Year: 2012 PMID： 22704203 DOI： 10.1016/j.chemosphere.2012.05.077
Source DB: PubMed Journal: Chemosphere ISSN： 0045-6535 Impact factor: 7.086