Literature DB >> 22704098

Population based study of long-term rates of surgery for urinary incontinence after radical prostatectomy for prostate cancer.

Robert K Nam1, Sender Herschorn, D Andrew Loblaw, Ying Liu, Laurence H Klotz, Lesley K Carr, Ronald T Kodama, Aleksandra Stanimirovic, Vasundara Venkateswaran, Refik Saskin, Calvin H L Law, David R Urbach, Steven A Narod.   

Abstract

PURPOSE: Urinary incontinence can be a significant complication of radical prostatectomy. It can be treated with post-prostatectomy surgical procedures. The long-term rate of patients who undergo these surgeries, including artificial urinary sphincter or urethral sling insertion, is not well described. We examined the long-term rate of post-prostatectomy incontinence surgery and factors influencing it.
MATERIALS AND METHODS: We performed a population based study of 25,346 men who underwent radical prostatectomy for prostate cancer in Ontario, Canada between 1993 and 2006. We used hospital and cancer registry administrative data to identify patients from this cohort who were later treated with surgery for urinary incontinence.
RESULTS: Of the 25,346 patients 703 (2.8%) underwent artificial urinary sphincter insertion and 282 (1.1%) underwent urethral sling placement a median of 2.9 years after prostatectomy. The probability of an artificial urinary sphincter/sling procedure increased with time from prostatectomy. Cumulative 5, 10 and 15-year Kaplan-Meier rates of an artificial urinary sphincter/sling procedure were 2.6% (95% CI 2.4-2.8), 3.8% (95% CI 3.6-4.1) and 4.8% (95% CI 4.4-5.3), respectively. Factors predicting surgery for incontinence were patient age at radical prostatectomy (HR 1.24 per decade, 95% CI 1.11-1.38, p = 0.0002), radiotherapy after surgery (HR 1.61, 95% CI 1.36-1.90, p <0.0001) and surgeon volume (49 or greater prostatectomies per year) (HR 0.59, 95% CI 0.46-0.77, p <0.0001).
CONCLUSIONS: Of patients who undergo radical prostatectomy 5% are expected to be treated with surgery for urinary incontinence during a 15-year period. Increasing patient age, radiation treatment and low surgeon volume are associated with significantly higher risk.
Copyright © 2012 American Urological Association Education and Research, Inc. Published by Elsevier Inc. All rights reserved.

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Mesh:

Year:  2012        PMID: 22704098     DOI: 10.1016/j.juro.2012.04.005

Source DB:  PubMed          Journal:  J Urol        ISSN: 0022-5347            Impact factor:   7.450


  20 in total

1.  [Economic importance of postoperative urinary incontinence].

Authors:  V Lent; M Schultheis
Journal:  Urologe A       Date:  2015-11       Impact factor: 0.639

2.  Practice patterns of post-radical prostatectomy incontinence surgery in Ontario.

Authors:  Christopher J D Wallis; Sender Herschorn; Ying Liu; Lesley K Carr; Ronald T Kodama; Laurence H Klotz; Refik Saskin; Robert K Nam
Journal:  Can Urol Assoc J       Date:  2014-09       Impact factor: 1.862

Review 3.  Surgery for postprostatectomy incontinence: which procedure for which patient?

Authors:  Craig Comiter
Journal:  Nat Rev Urol       Date:  2015-01-06       Impact factor: 14.432

4.  Post Prostatectomy Vesicourethral Stenosis or Bladder Neck Contracture with Concomitant Urinary Incontinence: Our Experience and Recommendations.

Authors:  Shieh L Bang; Sachin Yallappa; Fatima Dalal; Yahia Z Almallah
Journal:  Curr Urol       Date:  2017-03-30

Review 5.  Robotic Surgical System for Radical Prostatectomy: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2017-07-07

6.  Case report of deep vein thrombosis caused by artificial urinary sphincter reservoir compressing right external iliac vein.

Authors:  Marcus J Yip; Ashu Jhamb; Jeremy R Goad
Journal:  Urol Ann       Date:  2015 Jan-Mar

Review 7.  Update on management of post-prostatectomy incontinence in 2013.

Authors:  Sender Herschorn
Journal:  Can Urol Assoc J       Date:  2013-09       Impact factor: 1.862

8.  Effect of radical prostatectomy surgeon volume on complication rates from a large population-based cohort.

Authors:  Ashraf Almatar; Christopher J D Wallis; Sender Herschorn; Refik Saskin; Girish S Kulkarni; Ronald T Kodama; Robert K Nam
Journal:  Can Urol Assoc J       Date:  2016 Jan-Feb       Impact factor: 1.862

9.  Duloxetine for the treatment of post-prostatectomy stress urinary incontinence.

Authors:  Donald Neff; Amy Guise; Michael L Guralnick; Peter Langenstroer; William A See; Kenneth M Jacobsohn; R Corey O'Connor
Journal:  Can Urol Assoc J       Date:  2013 May-Jun       Impact factor: 1.862

Review 10.  The Role of Urodynamics in Post-Prostatectomy Incontinence.

Authors:  Maria Arcila-Ruiz; Benjamin M Brucker
Journal:  Curr Urol Rep       Date:  2018-02-26       Impact factor: 3.092

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