Literature DB >> 22698062

Multicolor super-resolution DNA imaging for genetic analysis.

Murat Baday1, Aaron Cravens, Alex Hastie, Hyeongjun Kim, Deren E Kudeki, Pui-Yan Kwok, Ming Xiao, Paul R Selvin.   

Abstract

Many types of cancer and neurodegenerative diseases are caused by abnormalities and variations in the genome. We have designed a high-resolution imaging technique with high throughput and low cost for determining structural variations of genes related to genetic diseases. We initially mapped all seven nicking sites of Nb.BbvCI endonuclease enzyme on lambda DNA. Then we resolved densely labeled patterns of 107 nicking sites on human BAC DNA that is digested by Nb.BsmI and Nb.BbvCI endonuclease enzymes. This high density resulted in several dyes being closer together than the diffraction limit. Overall, detailed DNA nicking sites mapping with 100 bp resolution was achieved, which has the potential to reveal information about genetic variance and to facilitate medical diagnosis of several genetic diseases.

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Year:  2012        PMID: 22698062      PMCID: PMC3880789          DOI: 10.1021/nl302069q

Source DB:  PubMed          Journal:  Nano Lett        ISSN: 1530-6984            Impact factor:   11.189


  30 in total

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Authors:  Ming Xiao; Matthew P Gordon; Angie Phong; Connie Ha; Ting-Fung Chan; Dongmei Cai; Paul R Selvin; Pui-Yan Kwok
Journal:  Hum Mutat       Date:  2007-09       Impact factor: 4.878

2.  Multicolor super-resolution imaging with photo-switchable fluorescent probes.

Authors:  Mark Bates; Bo Huang; Graham T Dempsey; Xiaowei Zhuang
Journal:  Science       Date:  2007-08-16       Impact factor: 47.728

3.  An oxygen scavenging system for improvement of dye stability in single-molecule fluorescence experiments.

Authors:  Colin Echeverría Aitken; R Andrew Marshall; Joseph D Puglisi
Journal:  Biophys J       Date:  2007-10-05       Impact factor: 4.033

4.  Psoriasis is associated with increased beta-defensin genomic copy number.

Authors:  Edward J Hollox; Ulrike Huffmeier; Patrick L J M Zeeuwen; Raquel Palla; Jesús Lascorz; Diana Rodijk-Olthuis; Peter C M van de Kerkhof; Heiko Traupe; Gys de Jongh; Martin den Heijer; André Reis; John A L Armour; Joost Schalkwijk
Journal:  Nat Genet       Date:  2007-12-02       Impact factor: 38.330

5.  Rapid DNA mapping by fluorescent single molecule detection.

Authors:  Ming Xiao; Angie Phong; Connie Ha; Ting-Fung Chan; Dongmei Cai; Lucinda Leung; Eunice Wan; Amy L Kistler; Joseph L DeRisi; Paul R Selvin; Pui-Yan Kwok
Journal:  Nucleic Acids Res       Date:  2006-12-14       Impact factor: 16.971

6.  DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome.

Authors:  Timothy J Ley; Elaine R Mardis; Li Ding; Bob Fulton; Michael D McLellan; Ken Chen; David Dooling; Brian H Dunford-Shore; Sean McGrath; Matthew Hickenbotham; Lisa Cook; Rachel Abbott; David E Larson; Dan C Koboldt; Craig Pohl; Scott Smith; Amy Hawkins; Scott Abbott; Devin Locke; Ladeana W Hillier; Tracie Miner; Lucinda Fulton; Vincent Magrini; Todd Wylie; Jarret Glasscock; Joshua Conyers; Nathan Sander; Xiaoqi Shi; John R Osborne; Patrick Minx; David Gordon; Asif Chinwalla; Yu Zhao; Rhonda E Ries; Jacqueline E Payton; Peter Westervelt; Michael H Tomasson; Mark Watson; Jack Baty; Jennifer Ivanovich; Sharon Heath; William D Shannon; Rakesh Nagarajan; Matthew J Walter; Daniel C Link; Timothy A Graubert; John F DiPersio; Richard K Wilson
Journal:  Nature       Date:  2008-11-06       Impact factor: 49.962

7.  Lineage-specific biology revealed by a finished genome assembly of the mouse.

Authors:  Deanna M Church; Leo Goodstadt; Ladeana W Hillier; Michael C Zody; Steve Goldstein; Xinwe She; Carol J Bult; Richa Agarwala; Joshua L Cherry; Michael DiCuccio; Wratko Hlavina; Yuri Kapustin; Peter Meric; Donna Maglott; Zoë Birtle; Ana C Marques; Tina Graves; Shiguo Zhou; Brian Teague; Konstantinos Potamousis; Christopher Churas; Michael Place; Jill Herschleb; Ron Runnheim; Daniel Forrest; James Amos-Landgraf; David C Schwartz; Ze Cheng; Kerstin Lindblad-Toh; Evan E Eichler; Chris P Ponting
Journal:  PLoS Biol       Date:  2009-05-26       Impact factor: 8.029

8.  Optical mapping of the Mycobacterium avium subspecies paratuberculosis genome.

Authors:  Chia-wei Wu; Timothy M Schramm; Shiguo Zhou; David C Schwartz; Adel M Talaat
Journal:  BMC Genomics       Date:  2009-01-15       Impact factor: 3.969

9.  Optical mapping as a routine tool for bacterial genome sequence finishing.

Authors:  Phil Latreille; Stacie Norton; Barry S Goldman; John Henkhaus; Nancy Miller; Brad Barbazuk; Helge B Bode; Creg Darby; Zijin Du; Steve Forst; Sophie Gaudriault; Brad Goodner; Heidi Goodrich-Blair; Steven Slater
Journal:  BMC Genomics       Date:  2007-09-14       Impact factor: 3.969

10.  Validation of rice genome sequence by optical mapping.

Authors:  Shiguo Zhou; Michael C Bechner; Michael Place; Chris P Churas; Louise Pape; Sally A Leong; Rod Runnheim; Dan K Forrest; Steve Goldstein; Miron Livny; David C Schwartz
Journal:  BMC Genomics       Date:  2007-08-15       Impact factor: 3.969

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  17 in total

1.  Micro- and nanofluidic technologies for epigenetic profiling.

Authors:  Toshiki Matsuoka; Byoung Choul Kim; Christopher Moraes; Minsub Han; Shuichi Takayama
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2.  Distribution of distances between DNA barcode labels in nanochannels close to the persistence length.

Authors:  Wesley F Reinhart; Jeff G Reifenberger; Damini Gupta; Abhiram Muralidhar; Julian Sheats; Han Cao; Kevin D Dorfman
Journal:  J Chem Phys       Date:  2015-02-14       Impact factor: 3.488

3.  Channeling DNA for optical mapping.

Authors:  Yael Michaeli; Yuval Ebenstein
Journal:  Nat Biotechnol       Date:  2012-08       Impact factor: 54.908

4.  Super-resolution mbPAINT for optical localization of single-stranded DNA.

Authors:  Jixin Chen; Alberto Bremauntz; Lydia Kisley; Bo Shuang; Christy F Landes
Journal:  ACS Appl Mater Interfaces       Date:  2013-09-27       Impact factor: 9.229

5.  Toward single-molecule optical mapping of the epigenome.

Authors:  Michal Levy-Sakin; Assaf Grunwald; Soohong Kim; Natalie R Gassman; Anna Gottfried; Josh Antelman; Younggyu Kim; Sam O Ho; Robin Samuel; Xavier Michalet; Ron R Lin; Thomas Dertinger; Andrew S Kim; Sangyoon Chung; Ryan A Colyer; Elmar Weinhold; Shimon Weiss; Yuval Ebenstein
Journal:  ACS Nano       Date:  2013-12-20       Impact factor: 15.881

6.  Inhibitors of SCF-Skp2/Cks1 E3 ligase block estrogen-induced growth stimulation and degradation of nuclear p27kip1: therapeutic potential for endometrial cancer.

Authors:  Savvas C Pavlides; Kuang-Tzu Huang; Dylan A Reid; Lily Wu; Stephanie V Blank; Khushbakhat Mittal; Lankai Guo; Eli Rothenberg; Bo Rueda; Timothy Cardozo; Leslie I Gold
Journal:  Endocrinology       Date:  2013-09-13       Impact factor: 4.736

7.  Single-molecule DNA-mapping and whole-genome sequencing of individual cells.

Authors:  Rodolphe Marie; Jonas N Pedersen; Loic Bærlocher; Kamila Koprowska; Marie Pødenphant; Céline Sabatel; Maksim Zalkovskij; Andrej Mironov; Brian Bilenberg; Neil Ashley; Henrik Flyvbjerg; Walter F Bodmer; Anders Kristensen; Kalim U Mir
Journal:  Proc Natl Acad Sci U S A       Date:  2018-10-15       Impact factor: 11.205

8.  Small quantum dots conjugated to nanobodies as immunofluorescence probes for nanometric microscopy.

Authors:  Yong Wang; En Cai; Tobias Rosenkranz; Pinghua Ge; Kai Wen Teng; Sung Jun Lim; Andrew M Smith; Hee Jung Chung; Frederick Sachs; William N Green; Philip Gottlieb; Paul R Selvin
Journal:  Bioconjug Chem       Date:  2014-11-25       Impact factor: 4.774

9.  Combing of genomic DNA from droplets containing picograms of material.

Authors:  Jochem Deen; Wouter Sempels; Raf De Dier; Jan Vermant; Peter Dedecker; Johan Hofkens; Robert K Neely
Journal:  ACS Nano       Date:  2015-01-08       Impact factor: 15.881

10.  A fast and scalable kymograph alignment algorithm for nanochannel-based optical DNA mappings.

Authors:  Charleston Noble; Adam N Nilsson; Camilla Freitag; Jason P Beech; Jonas O Tegenfeldt; Tobias Ambjörnsson
Journal:  PLoS One       Date:  2015-04-13       Impact factor: 3.240

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