Literature DB >> 22695810

Calcium handling and atrial fibrillation.

Jordi Heijman1, Niels Voigt, Stanley Nattel, Dobromir Dobrev.   

Abstract

Atrial fibrillation (AF) is the most prevalent sustained cardiac arrhythmia in the clinical setting. It is associated with substantial cardiovascular morbidity and mortality. Recent research has indicated that abnormal Ca(2+) handling plays a critical role in the induction and maintenance of AF, contributing to ectopic activity, AF-maintaining reentry circuits and related prothrombotic atrial hypocontractility. The AF-specific Ca(2+)-handling abnormalities may constitute viable therapeutic approaches to treat AF. Here, we review the causes, consequences, and therapeutic implications of altered atrial Ca(2+) handling for AF pathophysiology.

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22695810     DOI： 10.1007/s10354-012-0109-9

Source DB:  PubMed          Journal:  Wien Med Wochenschr        ISSN： 0043-5341


  30 in total

1.  Contribution of BK(Ca)-channel activity in human cardiac fibroblasts to electrical coupling of cardiomyocytes-fibroblasts.

Authors:  Ya-Jean Wang; Ruey J Sung; Ming-Wei Lin; Sheng-Nan Wu
Journal:  J Membr Biol       Date:  2007-05-04       Impact factor: 1.843

2.  Cellular mechanisms of depressed atrial contractility in patients with chronic atrial fibrillation.

Authors:  U Schotten; J Ausma; C Stellbrink; I Sabatschus; M Vogel; D Frechen; F Schoendube; P Hanrath; M A Allessie
Journal:  Circulation       Date:  2001-02-06       Impact factor: 29.690

3.  Human atrial action potential and Ca2+ model: sinus rhythm and chronic atrial fibrillation.

Authors:  Eleonora Grandi; Sandeep V Pandit; Niels Voigt; Antony J Workman; Dobromir Dobrev; José Jalife; Donald M Bers
Journal:  Circ Res       Date:  2011-09-15       Impact factor: 17.367

4.  Inhibition of CaMKII phosphorylation of RyR2 prevents induction of atrial fibrillation in FKBP12.6 knockout mice.

Authors:  Na Li; Tiannan Wang; Wei Wang; Michael J Cutler; Qiongling Wang; Niels Voigt; David S Rosenbaum; Dobromir Dobrev; Xander H T Wehrens
Journal:  Circ Res       Date:  2011-12-08       Impact factor: 17.367

Review 5.  Molecular determinants of cardiac fibroblast electrical function and therapeutic implications for atrial fibrillation.

Authors:  Lixia Yue; Jia Xie; Stanley Nattel
Journal:  Cardiovasc Res       Date:  2010-10-20       Impact factor: 10.787

6.  Defective cardiac ryanodine receptor regulation during atrial fibrillation.

Authors:  John A Vest; Xander H T Wehrens; Steven R Reiken; Stephan E Lehnart; Dobromir Dobrev; Parag Chandra; Peter Danilo; Ursula Ravens; Michael R Rosen; Andrew R Marks
Journal:  Circulation       Date:  2005-04-26       Impact factor: 29.690

Review 7.  The ryanodine receptor channel as a molecular motif in atrial fibrillation: pathophysiological and therapeutic implications.

Authors:  Dobromir Dobrev; Niels Voigt; Xander H T Wehrens
Journal:  Cardiovasc Res       Date:  2010-10-12       Impact factor: 10.787

8.  Common variants in KCNN3 are associated with lone atrial fibrillation.

Authors:  Patrick T Ellinor; Kathryn L Lunetta; Nicole L Glazer; Arne Pfeufer; Alvaro Alonso; Mina K Chung; Moritz F Sinner; Paul I W de Bakker; Martina Mueller; Steven A Lubitz; Ervin Fox; Dawood Darbar; Nicholas L Smith; Jonathan D Smith; Renate B Schnabel; Elsayed Z Soliman; Kenneth M Rice; David R Van Wagoner; Britt-M Beckmann; Charlotte van Noord; Ke Wang; Georg B Ehret; Jerome I Rotter; Stanley L Hazen; Gerhard Steinbeck; Albert V Smith; Lenore J Launer; Tamara B Harris; Seiko Makino; Mari Nelis; David J Milan; Siegfried Perz; Tõnu Esko; Anna Köttgen; Susanne Moebus; Christopher Newton-Cheh; Man Li; Stefan Möhlenkamp; Thomas J Wang; W H Linda Kao; Ramachandran S Vasan; Markus M Nöthen; Calum A MacRae; Bruno H Ch Stricker; Albert Hofman; André G Uitterlinden; Daniel Levy; Eric Boerwinkle; Andres Metspalu; Eric J Topol; Aravinda Chakravarti; Vilmundur Gudnason; Bruce M Psaty; Dan M Roden; Thomas Meitinger; H-Erich Wichmann; Jacqueline C M Witteman; John Barnard; Dan E Arking; Emelia J Benjamin; Susan R Heckbert; Stefan Kääb
Journal:  Nat Genet       Date:  2010-02-21       Impact factor: 38.330

Review 9.  Calcium handling abnormalities in atrial fibrillation as a target for innovative therapeutics.

Authors:  Dobromir Dobrev; Stanley Nattel
Journal:  J Cardiovasc Pharmacol       Date:  2008-10       Impact factor: 3.105

10.  Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.

Authors:  Xiao Yan Qi; Yung-Hsin Yeh; Ling Xiao; Brett Burstein; Ange Maguy; Denis Chartier; Louis R Villeneuve; Bianca J J M Brundel; Dobromir Dobrev; Stanley Nattel
Journal:  Circ Res       Date:  2008-08-21       Impact factor: 17.367
View more
  15 in total

1.  Synchronization of Triggered Waves in Atrial Tissue.

Authors:  Yohannes Shiferaw; Gary L Aistrup; John A Wasserstrom
Journal:  Biophys J       Date:  2018-08-18       Impact factor: 4.033

Review 2.  Calcium-mediated cellular triggered activity in atrial fibrillation.

Authors:  Dobromir Dobrev; Xander H T Wehrens
Journal:  J Physiol       Date:  2017-03-22       Impact factor: 5.182

Review 3.  Store-Operated Calcium Entry in the Cardiovascular System.

Authors:  Xian Liu; Zui Pan
Journal:  Adv Exp Med Biol       Date:  2021       Impact factor: 2.622

4.  Remodeling Promotes Proarrhythmic Disruption of Calcium Homeostasis in Failing Atrial Myocytes.

Authors:  Yohannes Shiferaw; Gary L Aistrup; William E Louch; J A Wasserstrom
Journal:  Biophys J       Date:  2019-12-18       Impact factor: 4.033

Review 5.  Investigating interactions between epicardial adipose tissue and cardiac myocytes: what can we learn from different approaches?

Authors:  Katja Rietdorf; Hilary MacQueen
Journal:  Br J Pharmacol       Date:  2017-01-22       Impact factor: 8.739

6.  Pleiotropic effects of antiarrhythmic agents: dronedarone in the treatment of atrial fibrillation.

Authors:  Jordi Heijman; Gerd Heusch; Dobromir Dobrev
Journal:  Clin Med Insights Cardiol       Date:  2013-08-11

7.  Disrupted calcium release as a mechanism for atrial alternans associated with human atrial fibrillation.

Authors:  Kelly C Chang; Jason D Bayer; Natalia A Trayanova
Journal:  PLoS Comput Biol       Date:  2014-12-11       Impact factor: 4.475

Review 8.  Calcium dysregulation in atrial fibrillation: the role of CaMKII.

Authors:  Jordi Heijman; Niels Voigt; Xander H T Wehrens; Dobromir Dobrev
Journal:  Front Pharmacol       Date:  2014-03-04       Impact factor: 5.810

9.  Spontaneous, pro-arrhythmic calcium signals disrupt electrical pacing in mouse pulmonary vein sleeve cells.

Authors:  Katja Rietdorf; Martin D Bootman; Michael J Sanderson
Journal:  PLoS One       Date:  2014-02-20       Impact factor: 3.240

Review 10.  Concise Review: Criteria for Chamber-Specific Categorization of Human Cardiac Myocytes Derived from Pluripotent Stem Cells.

Authors:  Christopher Kane; Cesare M N Terracciano
Journal:  Stem Cells       Date:  2017-06-27       Impact factor: 6.277
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.