Literature DB >> 22691104

Antibiotic use in infants in the first year of life in five European countries.

Jose Stam1, Margriet van Stuijvenberg, Christoph Grüber, Fabio Mosca, Sertac Arslanoglu, Gaetano Chirico, Christian P Braegger, Josef Riedler, Günther Boehm, Pieter J J Sauer.   

Abstract

AIM: To assess in infants the number of illness episodes treated with antibiotics and prescription rates in five European countries.
METHODS: This study was embedded in a multicenter nutritional intervention study and was conducted in five European countries. Infants were followed until 1 year of age. Illness episodes and prescriptions of systemic antibiotics were recorded by the parents.
RESULTS: Illness episodes were caused by upper respiratory tract infections (URTIs) in 55-64% and by otitis media (OM) in 2-6.8%. URTIs were statistically significant and more frequently treated with antibiotics in Italy (18.8%), and less frequently in Switzerland (1.4%). OM was statistically significant and less frequently treated with antibiotics in the Netherlands (55%) when compared to Italy (82%). The antibiotic prescription rate varied between countries, ranging from 0.2 to 1.3 prescriptions per infant per year.
CONCLUSIONS: As the frequency of illness episodes did not differ between countries, other factors, such as physician's attitude, parental pressure or other socio-economic determinants, most likely play a role in antibiotic prescribing habits in the first year of life.
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.

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Year:  2012        PMID: 22691104     DOI: 10.1111/j.1651-2227.2012.02728.x

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  19 in total

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